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		题名	作者	年代	出处	被引量
	1	Folic acid supplementation inhibits recurrence of colorectal adenomas:A randomized chemoprevention trial显示文摘AIM: To determine whether folic acid supplementation will reduce the recurrence of colorectal adenomas, the precursors of colorectal cancer, we performed a double-blind placebo-controlled trial in patients with adenomatous polyps. METHODS: In the current double-blind, placebo-controlled trial at this VA Medical Center, patients with colorectal adenomas were randomly assigned to receive either a daily 5 mg dose of folic acid or a matched identical placebo for 3 years. All polyps were removed at baseline colonoscopy and each patient had a follow up colonoscopy at 3 years. The primary endpoint was a reduction in the number of recurrent adenomas at 3 years. RESULTS: Of 137 subjects, who were eligible after confirmation of polyp histology and run-in period to conform compliance, 94 completed the study; 49 in folic acid group and 45 in placebo group. Recurrence of adenomas at 3-year was compared between the two groups. The mean number of recurrent polyps at 3-year was 0.36 (SD, 0.69) for folic acid treated patients compared to 0.82 (SD, 1.17) for placebo treated subjects, resulting in a 3-fold increase in polyp recurrence in the placebo group. Patients below 70 years of age and those with left-sided colonicadenomas or advanced adenomas responded better to folic acid supplementation. CONCLUSION: High dose folic acid supplementation is associated with a signif icant reduction in the recurrence of colonic adenomas suggesting that folic acid may be an effective chemopreventive agent for colorectal neoplasia.	Richard Jaszewski Sabeena Misra Martin Tobi Nadeem Ullah Jo Ann Naumoff Omer Kucuk Edi Levi Bradley N Axelrod Bhaumik B Patel Adhip PN Majumdar	2008	World Journal of Gastroenterology2008，14，28：	10
	2	Small-focus integral fiber lenses:modeling with the segmented beam-propagation method and nearfield characterization显示文摘	Axelrod N Lewis A Yosef N B		0，，：	1
	3	Neuropsychological sequelae ofheatstroke 显示文摘	Axelrod B N Woodard J L	2015	Int J Neurosci2015，70，34：	1
	4	Adjuvant whole abdominal irradiation in clinical stages Ⅰ and Ⅱ papillary serous or clear cell carcinoma of the endometrium:a phase Ⅱ study of the Gynecologic Oncology Group显示文摘	SUTTON G AXELROD J H BUNDY B N	2006	Gynecol Oncol2006，100，2：	1
	5	Neuropsychological symptoms associated with low - level exposure to solvents and (meth) acrylates among nail technicians 显示文摘	LoSasso G L Rapport L J Axelrod B N	2001	Neuropsychiatry neuropsychology and behavioral neurology2001，14，3：	1

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