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| 1 | Behind the curtain of non-coding RNAs; long non-coding RNAs regulating hepatocarcinogenesis显示文摘Hepatocellular carcinoma(HCC) is one of the most common and aggressive cancers worldwide. HCC is the fifth common malignancy in the world and the second leading cause of cancer death in Asia. Long non-coding RNAs(lncRNAs) are RNAs with a length greater than 200 nucleotides that do not encode proteins. lncRNAs can regulate gene expression and protein synthesis in several ways by interacting with DNA, RNA and proteins in a sequence specific manner. They could regulate cellular and developmental processes through either gene inhibition or gene activation. Many studies have shown that dysregulation of lncRNAs is related to many human diseases such as cardiovascular diseases, genetic disorders, neurological diseases, immune mediated disorders and cancers. However, the study of lncRNAs is challenging as they are poorly conserved between species, their expression levels aren't as high as that of m RNAs and have great interpatient variations. The study of lncRNAs expression in cancers have been a breakthrough as it unveils potential biomarkers and drug targets for cancer therapy and helps understand the mechanism of pathogenesis. This review discusses many long non-coding RNAs and their contribution in HCC, their role in development, metastasis, and prognosis of HCC and how to regulate and target these lncRNAs as a therapeutic tool in HCC treatment in the future. | Aya El Khodiry Menna Afify Hend M El Tayebi | 2018 | World Journal of Gastroenterology2018，24，5： | 9 |
| 2 | Evaluation of different media in the reprodution of Paecilomyces lilacinus显示文摘 | LOPEZ M Z AYAS M A FRAGA M | 1992 | Revista de Protection Vegetal1992，7，： | 1 |
| 3 | Gibberellin modulates anther development in rice via the transcriptional regulation of GAMYB显示文摘 | Aya K Ueguchi-Tanaka M Kondo M | | 0，，： | 1 |
| 4 | Nodal status and clinical outcomes in a large cohort of patients with triple-negative breast cancer显示文摘 | Hernandez Aya L F Chavez Macgegor M Lei X | | 0，，19： | 1 |
| 5 | Giant osteoma of the frontal sinus 显示文摘 | Ataman M Ayas K Gursel B | 1993 | Rhinology1993，31，4： | 1 |
| 6 | Does adding ATG to the GVHD prophylaxis regimen help reduce its incidence显示文摘 | Ayas M Al-Mahr M Al-Jefri A | 2003 | Bone Marrow Transplant2003，31，： | 1 |
| 7 | Griffiths LR:High - resolution loss of heterozygosity screening im- plicates PTPRJ as a potential tumor suppressor gene that affects Suscept - ibility to non - hodgkin' s lymphoma 显示文摘 | Aya - Bonilla C Green M R Camilleri E | 2013 | Genes Chromosom Cancer2013，52，5： | 1 |
| 8 | Cost-effectiveness of oral appliances in the treat-ment of obstructive sleep apnoea - hypopnoea显示文摘 | Sadatsafavi M ’ Marra CA Ayas NT | 2009 | Sleep Breath2009，13，3： | 1 |
| 9 | Clinical characteris- tics and outcome of children with biphenotypic acute leukemia 显示文摘 | A1-Seraihy AS Owaidah TM Ayas M | 2009 | Haematologica2009，94，12： | 1 |
| 10 | Protection activity of a novel probiotic strain of Bacillus subtilis against Salmonella Enteriti- dis infection显示文摘 | THIRABUNYANON M THONGWITI'AYA N | 2012 | Res Vet Sci2012，93，1： | 1 |
| 11 | Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: resuits of a meta analysis显示文摘 | Davidson W J Dorscheid D Spragg R Schulzer M Mak E Ayas N T | 2006 | Crit Care2006，10，： | 1 |
| 12 | An investigation ofconflict resolution strategies of adolescents显示文摘 | Ayas T Deniz M Kagan M | 2010 | Proce-dia-Social and Behavioral Sciences2010，2，2： | 1 |
| 13 | Nodal status and clinical outcomes in a large cohort of patients with triple- negative breast cancer 显示文摘 | Hernandez- Aya LF Chavez- Macgregor M Lei X | 2011 | J Clin Oncol2011，29，19： | 1 |
| 14 | De novo transcriptome as?sembly of a fern, LygodiumJaponicum, and a web resource data?base, Ljtrans DB显示文摘 | Aya K Kobayashi M TanakaJ | 2015 | Plant & Cell Physiology2015，56，1： | 1 |
| 15 | NF-kap- paB-inducing kinase controls lymphocyte and osteoclast activi ties in inflammatory arthritis显示文摘 | Aya K Alhawagri M Hagen-Stap leton A | 2005 | J Clin Invest2005，115，7： | 1 |
| 16 | Treatment of high strength industrial wastewater using extended aeration immersed microfiltration(EAM)process显示文摘 | M M N Megat Johari H Nagacka H Aya | 2002 | Desalination2002，149，： | 1 |
| 17 | Potential anti-tumor effect of IFN-λ2 (IL-28A) against human lung cancer cells显示文摘 | Yasuhiro T Shunsuke E Aya M | 2012 | Lung Cancer2012，78，3： | 1 |
| 18 | Intravenous nicardipine for severe hypertension in pre-eclampsia--effects of an acute treatment on mother and foetus显示文摘 | AYA AG MANGIN R HOFFET M | 1999 | Intensive Care Med1999，25，11： | 1 |
| 19 | Second allogeneic bone marrow transplantation after myeloablative conditioning analysis of 43 cases from single institution显示文摘 | Al Qurashi F Ayas M Al Sharif F | 2004 | Hematology2004，9，2： | 1 |
| 20 | Cardiovascular consequences of sleep apnea 显示文摘 | Golbidi S Badran M Ayas N | 2012 | Pro Clin Biol Res2012，190，2： | 1 |
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