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| 1 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 2 | Rock fracture toughness determination by the Brazilian test显示文摘 | Guo H Aziz I Schmidt L C | 1993 | Engineering Geology1993，33，2： | 1 |
| 3 | Rock fracture toughness determination by the Brazilian test显示文摘 | GUO H AZIZ N I SCHMIDT L C | 1993 | Engineering Geology1993，33，3： | 1 |
| 4 | Reduction of fungi and mycotoxins formation in seeds by gamma irradiation 显示文摘 | Aziz N H Moussa L A A | 2004 | Journal of Food Safety2004，24，2： | 1 |
| 5 | Highly efficient magnetically separable TiO2-graphene oxide supported SrFe12O19 for direct sunlight-driven photoactivity显示文摘 | Abd Aziz A Yau Y H Puma G L | 2014 | Chemical Engineering Journal2014，235，： | 1 |
| 6 | Influence of gamma-radiation on mycotoxin producing moulds and mycotoxins in fruits 显示文摘 | Aziz N H Moussa L A A | 2002 | Food Control2002，13，45： | 1 |
| 7 | Single nucleotide polymorphisms in the human interleukin-1Bgene affect transcription according to haplotype context显示文摘 | Chen H Wilkins L M Aziz N | 2006 | Human Molecular Genetics2006，15，4： | 1 |
| 8 | Influence of gammairradiation and maize lipids on the production of aflatoxin BI by Aspergillus flavus显示文摘 | AZIZ N H EL-ZEANY S A MOUSSA L A | 2002 | Nahrung2002，46，5： | 1 |
| 9 | Semi- Analytical Modeling of the Performance of Intelligent Well Completions 显示文摘 | Valvatne P H Durlofsky L J Aziz K | 2001 | SPE2001，6，： | 1 |
| 10 | The value of Ureaplasma urealyticum tracheal culture and treatment in premature infants following an acute respiratory deterioration显示文摘 | Mhanna M J Delong L J Aziz H F | 2003 | J Perinatol2003，23，7： | 1 |
| 11 | Influence of gamma-radiation on mycotoxin producing moulds and mycoloxins in fruits 显示文摘 | Aziz N H Moussa L A A | 2002 | Food Control2002，13，： | 1 |
| 12 | Rock fracture-toughness determination by the Brazilian test显示文摘 | GUO H AZIZ N I SCHMIDT L C | 1993 | International Journal of Cardiology1993，33，3： | 1 |
| 13 | comparative antibacterial and antifimgal effects of some phenolic compands显示文摘 | Aziz N H Farag S E Monsa L A | 1998 | Microbios1998，93，374： | 1 |
| 14 | Rock fracture toughness determi- nation by the Brazilian test 显示文摘 | Guo H Aziz N I Schmidt L C | 1993 | Engineering Geology1993，33，： | 1 |
| 15 | 1-Methyl-2-(anthry)-imidazo-phenanthroline:A high efficient electron-transfer compound and a bright blue-light emitter for electro-lu minescent devices显示文摘 | Wang R Y Jia W L Aziz H | 2005 | Advanced functional materials2005，15，： | 1 |
| 16 | Studies of electrical and mechanical properties of poly(vinyl chloride)mixed with electri- cally conductive additives显示文摘 | Saad A L G Aziz H A Dimitry O I H | 2004 | Journal of Applied Polymer Sci ence2004，91，3： | 1 |
| 17 | Rock fracture toughness determination by the brazilian test显示文摘 | Guo H Aziz N I Schmidt L C | 1993 | Engineering Geology1993，33，： | 1 |
| 18 | Modelling of geochemical and isotopic changes in a column experiment for degradation of TCE by zero-valent iron 显示文摘 | Prommer H Aziz L H Bolafio N | 2008 | Journal of Contaminant Hydrology2008，97，12： | 1 |
| 19 | Putative role of carbon monoxide signaling pathway in penile erectile function显示文摘 | Abdel Aziz M T Mostafa T Atta H Wassef M A Fouad H H Rashed L A | 2009 | J Sex Med2009，6，： | 1 |
| 20 | : (1)-adrenergic receptor polymorphisms and response to :- blockade in the African- American study of kidney disease and hypertension (AASK) 显示文摘 | Lee J Aziz H Liu L | 2011 | Am J Hypertens2011，24，6： | 1 |
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