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3篇 您的检索式:作者名="B.J.M. Mulder"
    题名 作者 年代 出处 被引量
1先天性心脏病中的肺动脉高压:来自一项荷兰注册研究的流行病学结果显示文摘背景:与先天性心脏病有关的肺动脉高压(PAH),通常是大量体循环向肺循环分流的结果,常常导致右室心力衰竭和早期死亡。本研究旨在确定一项先天性心脏病国家注册研究所登记成年患者中的PAH患病率,评价患者特征和PAH之间的关系。Duffels M.G.J. Engelfriet P.M. Berger R.M.F. B.J.M. Mulder 韩瑞娟 2007世界核心医学期刊文摘(心脏病学分册)2007,,11:4
2法洛四联症患者肺动脉瓣置换后自体移植物功能的长期随访显示文摘Aims: To analyse the long-term outcomes after pulmonary valve replacement(PVR) in patients with a previous correction for tetralogy of Fallot. Methods and results: In a retrospective study, 158 adult patients with a diagnosis of tetralogy of Fallot, who had undergone a PVR after initial total correction in childhood, were identified from the CONCOR(CONgenital CORvitia) registry. All patients underwent 175 PVRs between June 1986 and June 2005. To analyse the predictors for homograft dysfunction and adverse events(death, reoperations, balloon angioplasty), Cox-regression analysis was performed. Overall freedom from significant homograft dysfunction was 66%after 5 years and 47%after 10 years. We could not identify predictors for combined homograft dysfunction. Event-free survival was 78%at 10 years and 68%at 15 years after PVR. Both early significant pulmonary regurgitation(PR)(HR 6.8, P=0.017) and pulmonary stenosis(PS)(HR 4.0, P=0.037) after surgery were associated with adverse events. When analysing direct post-operative PR or PS,we observed that in patients with severe, pre-operative PR, right ventricular aneurysm/patch resection resulted in a lower post-operative PR(mean difference grade 0.38±0.14, P=0.01). Less significant post-operative PS was associated with a higher diameter of the homograft(HR 0.37, P=0.006). Conclusion: While 47%of the patients in our study were free from homograft dysfunction at 10 years after PVR, event-free survival after PVR remained fairly good(78%). Significant residual lesions directly after surgery influenced event-free survival. A smaller diameter of the pulmonary homograft and severe pre-surgical PR were related to early homograft dysfunction after surgery.Oosterhof T. Meijboom F.J. Vliegen H.W. B.J.M. Mulder 郭俊 2006世界核心医学期刊文摘(心脏病学分册)2006,,12:4
3马方综合征患者远离主动脉根部的远端扩张Engelfriet P.M. Boersma E. Tijssen J.G.P. B.J.M. Mulder 郭俊 2007世界核心医学期刊文摘(心脏病学分册)2007,0,1:0
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