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| 1 | Sodium fluoride induces apoptosis through reactive oxygen species-mediated endoplasmic reticulum stress pathway in Sertoli cells显示文摘Excessive fluoride exposure is known to contribute to reproductive system dysfunction,ultimately leading to pathological damage and apoptosis in cells. Although both oxidative and endoplasmic reticulum(ER) stresses have been implicated in fluorosis, the signaling pathways and their roles in sodium fluoride(Na F)-induced apoptosis of Sertoli cells have been sparsely described. In this study, oxidative damage, ER stress, and apoptosis were analyzed after Sertoli cells were treated with varying doses of Na F for 24 hr. Moreover, the antioxidant N-acetylcysteine(NAC) and pro-apoptotic transcription factor CHOP knockdown were used to clarify the precise interplay between reactive oxygen species(ROS), ER stress and their roles in NaF-induced apoptosis in Sertoli cells. The present study indicated that NaF significantly decreased cell viability and induced apoptosis in Sertoli cells. In addition, NaF exposure facilitated the accumulation of ROS and increased nuclear translocation of nuclear factor erythroid 2-related factor 2(Nrf2) in Sertoli cells. Treatment with NAC caused remarkable recovery from these NaF-induced responses. Meanwhile, excessive NaF triggered ER stress as evidenced by up-regulated glucose-regulated protein 78 k Da(GRP78), PKR-like ER kinase(PERK), phosphorylation of eukaryotic translation initiation factor 2α(p-eI F2α) and CCAAT/enhancer-binding protein-homologous protein(CHOP), without affecting total eukaryotic translation initiation factor 2α(e IF2α). NAC effectively blocked the activation of ER stress, suggesting that Na F-induced ROS is an early event that triggers ER stress. Taken together, the results demonstrate that the ROS-mediated ER stress pathway is the crucial mechanistic event involved in NaF-induced apoptosis of Sertoli cells. | Yang Yang Xinwei Lin Hui Huang Demin Feng Yue Ba Xuemin Cheng Liuxin Cui | 2015 | Journal of Environmental Sciences2015，27，4： | 10 |
| 2 | Serum calciotropic hormone levels, and dental fluorisis in children exposed to different concentrations of fluoride and iodine in drinking water显示文摘 | BA Yue ZHU Jiang-yuan YANG Yue-jin YU Bo HUANG Hui WANG Gang REN Li-jun CHENG Xue-min CUI Liu-xin ZHANG Ya-wei | 2010 | Chinese Medical Journal2010，，6： | 6 |
| 3 | High-performance optical chirp chain BOTDA by using a pattern recognition algorithm and the differential pulse-width pair technique显示文摘Optical chirp chain Brillouin optical time-domain analysis(OCC-BOTDA) has the capabilities of fast measurement, high Brillouin threshold, and freedom from the nonlocal effect;at the same time, however, it also has problems introduced by transient stimulated Brillouin scattering. The influence of the transient interaction is reflected as the broadened asymmetric Brillouin spectrum, the ghost peak, and the frequency shift of the main peak. This introduces difficulty in computing the fiber Brillouin frequency shift with good measurement accuracy. Besides, the OCC modulation causes additional noise due to the uneven amplitude response for different frequency components. In this work, we propose a high-performance OCC-BOTDA using the principal component analysis(PCA) based pattern recognition algorithm and differential pulse-width pair(DPP) technique.After building the Brillouin spectrum database(i.e., all patterns), the fiber intrinsic Brillouin frequency shift can be recognized by the PCA algorithm from a nonstandard Brillouin spectrum profile, resulting in good measurement accuracy. Meanwhile, the DPP technique, subtracting between two Brillouin signals generated by two wide-width pump pulses, is utilized to reduce the OCC modulation noise and avoid the pulse self-phase modulation effect in long-range BOTDA sensing. In the experiment, a temperature measurement with 1.3 MHz measurement precision, 4 m spatial resolution, and 5 s measurement time is achieved over a 100 km single-mode fiber. | BENZHANG WANG BAOHUA FAN DENGWANG ZHOU CHAO PANG YUE LI DEXIN BA YONGKANG DONG | 2019 | Photonics Research2019，7，6： | 5 |
| 4 | Consensus on clinical management of tumor-induced osteomalacia显示文摘Tumor-induced osteomalacia(TIO)is a rare paraneoplastic syndrome caused by excessive fibroblast growth factor 23(FGF23)production by a tumor,which often arises from a mesenchymal origin.[1-3]Most clinical symptoms of TIO are the consequences of prolonged FGF23-mediated hypophosphatemia as muscle weakness,bone pain,impaired mobility,and fractures.[4]Clinical diagnosis and management of TIO are challenging because knowledge about this condition is still restricted to a few specialized centers,leading to delay in diagnosis and appropriate treatment.The scope of the present consensus is to provide up-to-date guidance on the assessment and treatment of TIO. | Yan Jiang Xiang Li Li Huo Yong Liu Wei Lyu Lian Zhou Wei Yu Huan-Wen Wu Xiao-Ping Xing Mei Li Ou Wang Yue Chi Rui-Zhi Jiajue Yu Pei Jian-Min Liu Jian-Ming Ba Qiao Zhang Zhi-Feng Sheng Zhen-Lin Zhang Jia-Jun Zhao Salvatore Minisola Wei-Bo Xia on behalf of Chinese Society of Osteoporosis and Bone Mineral Research and Chinese Society of Endocrinology | 2021 | Chinese Medical Journal2021，，11： | 3 |
| 5 | Fluoride Exposure,Follicle Stimulating Hormone Receptor Gene Polymorphism and Hypothalamus-pituitary-ovarian Axis Hormones in Chinese Women显示文摘The effects of fluoride exposure on the functions of reproductive and endocrine systems have attracted widespread attention in academic circle nowadays.However,it is unclear whether the gene-environment interaction may modify | ZHAO Ming Xu ZHOU Guo Yu ZHU Jing Yuan GONG Biao HOU Jia Xiang ZHOU Tong DUAN Li Ju DING Zhong CUI Liu Xin BA Yue | 2015 | Biomedical and Environmental Sciences2015，28，9： | 2 |
| 6 | Osteogenic differentiation of adipose-derived stem cells prompted by low-intensity pulsed ultrasound显示文摘 | Yue Y Yang X Wei X Chen J Fu N Fu Y Ba K Li G Yao Y Liang C Zhang J Cai X Wang M | | 0，，： | 1 |
| 7 | Significant Polymorphisms of Vitamin D Receptor Gene(rs2189480 and rs3847987) Related to the Risk of Type 2 Diabetes in Henan Rural Area显示文摘Type 2 diabetes mellitus (T2DM) accounts for 90% of all diabetes cases and results in severe complications. It is a multifactorial metabolic disorder that results from a combination of resistance to insulin action and an inadequate compensatory insulin secretory response. The interaction between multiple genetic and environmental determinants has been considered to contribute to the pathogenesis of T2DM[1]. | HAN Han ZHAO Ming Xu WANG Yan WANG Jun REN Bing Nan GE Hui Na WANG Teng SUN Bei Bei BA Yue LI Wen Jie | 2019 | Biomedical and Environmental Sciences2019，32，1： | 1 |
| 8 | Polymorphisms in CYP2R1 Gene Associated with Serum Vitamin D Levels and Status in a Chinese Rural Population显示文摘Vitamin D, a fat-soluble vitamin and endocrine horm one, and it impacts various bone and extra-bone health, such as osteoporosis, diabetes, and cancer. The main circulating form of vitamin D is 25-hydroxyvitamin D [25(OH)D] and it is a useful clinical biomarker of vitamin D status. The Institute of Medicine (IOM) defines as vitamin D deficiency (VDD) when serum 25(OH)D concentration is less than 20 ng/mL⑴.Worldwide, VDD is recognized as a severe public health problem. In 2007, Holick estimated that globally over one billion people suffered from VDD or vitamin D insufficiency (VDI). In China, it has bee n reported that the prevale nee of VDD ranged from 38.8% to 91.2% in different regions. | WANG Yan HAN Han WANG Jun SHEN Fang YU Fei WANG Ling YU Song Cheng ZHANG Dong Dong SUN Hua Lei XUE Yuan BA Yue WANG Chong Jian LI Wen Jie | 2019 | Biomedical and Environmental Sciences2019，32，7： | 1 |
| 9 | COL1A2 gene polymorphisms (PvuII and RsaI), serum calciotropic hormone levels, and dental fluorosis显示文摘 | Huang Hui Ba Yue Cui Liuxin | 2008 | Community Dent Oral Epidemiol2008，36，： | 1 |
| 10 | Augmentation of central arterial pressure in Type 2 diabetes显示文摘 | Brooks BA Molyneaux LM Yue DK | 2001 | Diabetic Medicine2001，18，5： | 1 |
| 11 | Augmentation of central arterial pressure in type 2 diabetes显示文摘 | Brooks BA Molyneaux LM Yue DK | 2001 | Diabetic Medicine2001，18，5： | 1 |
| 12 | Promotional Marketing or Word-of-Mouth? Evidence from Online Restaurant Reviews显示文摘 | Xianghua Lu Sulin Ba Lihua Huang Yue Feng | 2013 | Information Systems Research2013，，3： | 1 |
| 13 | Pressure Analysis in a Com- pressor Cylinder Based on Detached Eddy Simulation and Dynamic Mesh 显示文摘 | YUE X J BA D C BAY S | 2013 | Proceedings of the Institution of Mechanical Engineers Part C:Journal of Mechanical Engineering Science2013，227，6： | 1 |
| 14 | Ahgmentation of central arterial pressure in Type 2 diabetes 显示文摘 | Brooks BA Molyneaux LM Yue DK | 2001 | Diabetic Medicine2001，18，5： | 1 |
| 15 | Non-destructive and distributed measurement of optical fiber diameter with nanometer resolution based on coherent forward stimulated Brillouin scattering显示文摘Precise control and measurement of the optical fiber diameter are vital for a range of fields,such as ultra-high sensitivity sensing and high-speed optical communication.Nowadays,the measurement of fiber diameter relies on point measurement schemes such as microscopes,which suffer from a tradeoff between the resolution and field of view.Handling the fiber can irreversibly damage the fiber samples,especially when multi-point measurements are required.To overcome these problems,we have explored a novel technique in which the mechanical properties of fibers are reflected by forward stimulated Brillouin scattering(FSBS),from which the diameters can be demodulated via the acoustic dispersion relation.The distributed FSBS spectra with narrow linewidths were recorded via the optimized optomechanical time-domain analysis system using coherent FSBS,thereby achieving a spatial resolution of 1 m over a fiber length of tens of meters.We successfully obtained the diameter distribution of unjacketed test fibers with diameters of 125μm and 80μm.The diameter accuracy was verified by high-quality scanning electron microscope images.We achieved a diameter resolution of 3.9 nm,virtually independent of the diameter range.To the best of our knowledge,this is the first demonstration of non-destructive and distributed fiber diameter monitoring with nanometer resolution. | Zijie Hua Dexin Ba Dengwang Zhou Yijia Li Yue Wang Xiaoyi Bao Yongkang Dong | 2021 | Light(Advanced Manufacturing)2021，2，4： | 1 |
| 16 | Performance analysis of unequal error protection distributed network coding based on fountain codes显示文摘 | Yue Jing Lin Zi-huai Ba Bao-ming et aL | 2014 | Wireless Communications Letters2014，3，3： | 1 |
| 17 | Artemisinin rewires the protein interaction network in cancer cells: network analysis, pathway identification, and target prediction 显示文摘 | Huang C Ba Q Yue Q | 2013 | Mol Biosyst2013，9，12： | 1 |
| 18 | Artemisinin rewires the protein interaction network in cancer cells: network analysis, pathway identification, and target prediction 显示文摘 | Huang C Ba Q Yue Q | 2013 | Mol Biosyst2013，9，12： | 1 |
| 19 | Effect of γ phase on mechanical behavior and detwinning evolution of directionally solidified Ni-Mn-Ga alloys under uniaxial compression显示文摘Specimens with single-phase martensite, net-like γ/martensite mixed structure and lamella-likeγ/martensite mixed structure were designed to investigate the effect of the γ phase on the mechanical behavior and the detwinning of non-modulated(NM) martensitic variant in Ni-rich Ni-Mn-Ga alloys under uniaxial compression. It can be found the existence of the γ phase significantly enhances the compressive stresses, and the net-like γ phase specimen presents a higher value of compressive strain than that of the lamella-like γ phase specimen. Especially, the detwinning plateau of the lamella-like γ phase specimen is almost invisible due to the martensite colonies with low Schmid factors. Finally, according to the calculation of deformation gradient tensor, we found that the tensors along compression direction(εzz) of net-like γ phase/martensite mixed structure specimen and single-phase martensite specimen are lower than that of the specimen with lamella-like γ phase/martensite mixed structure, which well explained the detwinning strain for these specimens. The present study not only highlights the role ofγ phase on the mechanical behavior, but also provides more guidelines for the mechanical training of Ni-Mn-Ga shape memory alloys. | Ying Niu Yue Wang Long Hou Lansong Ba Yanchao Dai Yves Fautrelle Zongbin Li Zhongming Rena Xi Li | 2021 | Journal of Materials Science & Technology2021，，7： | 0 |
| 20 | Weather and Birth Weight:Different Roles of Maternal and Neonatal GPR61 Promoter Methylation显示文摘Objectives It is unclear whether G protein-coupled receptor 61(GPR61)affecting body weight,plays a role in the association between birth weight and weather.This study aimed to assess the effects of prenatal weather and GPR61 on birth weight.Methods A total of 567 mother-newborn pairs were recruited in Houzhai Center Hospital during2011–2012.We detected the maternal and neonatal GPR61 promoter methylation levels,and obtained meteorological and air pollution data.Results A positive association was observed between maternal and neonatal GPR61 methylation levels,and both of them were affected by precipitation,relative humidity(RH)and daily temperature range(DTR).Birth weight was associated negatively with RH and positively with DTR(P<0.05).A significant association was observed between birth weight and neonatal GPR61 methylation.We observed that maternal GPR61 methylation seemed to modify associations between weather and birth weight(P_(interaction)<0.10),while neonatal GPR61 methylation mediated the effects of RH and DTR on birth weight(P<0.05).Conclusions Our findings revealed the significant associations among prenatal weather,GPR61 methylation and birth weight.Maternal GPR61 methylation may modify the susceptibility of birth weight to prenatal weather conditions,while neonatal GPR61 methylation may be a bridge of the effects of prenatal RH and DTR on birth weight. | LI Zhi Yuan GONG Yong Xiang YANG Meng CHAI Jian SUN Ren Jie LI Qin Yang HE Ya Nan HUANG Hui ZHANG Ya Wei BA Yue ZHOU Guo Yu | 2022 | Biomedical and Environmental Sciences2022，35，3： | 0 |
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