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| 1 | 根治性手术与短程放疗后行经肛门内镜显微手术(TEM)保留器官治疗早期直肠癌(TREC):一项随机、开放标签的可行性研究显示文摘背景:基于全直肠系膜切除(total mesorectal excision,TME)的根治性手术可能不是早期直肠癌的最佳一线治疗。选择性TME保留器官的策略可以减少治疗的不良反应,又不会显著影响肿瘤结果。该临床随机研究通过与TME比较,探讨器官保留策略的可行性。方法:TREC是一项在英国21个三级转诊中心进行的随机、开放标签的可行性研究。符合条件的受试者年龄≥18岁,分期为T2期或更早,最大直径不超过30 mm;排除淋巴结受累或转移的患者。患者按计算机随机分配(1:1)接受短程放疗保留器官,8~10周后行经肛门内镜显微手术(transanal endo⁃scopic microsurgery,TEM)或TME术。当TEM标本组织病理学特征提示局部复发风险增加时,患者被考虑计划早期转为TME。一项非随机前瞻性登记收集了认为不适合随机化的患者,因为每例患者都是按临床指征治疗的。主要终点为12、18和24个月的累积随机分组。次要结局为应用欧洲癌症研究与治疗组织(EORTC)QLQ C30和CR29量表对意向治疗人群的安全性、有效性和健康相关生活质量进行了评价。该研究已在ISRCTN注册中心注册,ISRCTN14422743。 | 佟伟华 BACH S P GILBERT A BROCK K | 2021 | 结直肠肛门外科2021，27，3： | 9 |
| 2 | Baseline risk of major bleeding in non-ST-segment-elevation myocardial infarction: the CRUSADE (Can Rapid risk stratifi cation of Unstable anginapatients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines) Bleeding Score 显示文摘 | Subherwal S Bach RG Chen AY | 2009 | Circulation2009，19，14： | 1 |
| 3 | Electrochemical Properties of Sol-gel Li4/3Ti5/3O12显示文摘 | BACH S PEREIRA-RAMOS J BAFFIER P N | 1999 | J Power Sources1999，8182，： | 1 |
| 4 | The Yersinia high- pathogenicity island is present in different members of the family Enterobacteriaceae显示文摘 | Bach S de Almeide A Carniel E | 2000 | FEMS Microbiol Lett2000，183，2： | 1 |
| 5 | Quantitative asses-ment of tactile allodynia in the rat paw显示文摘 | Chaplan S R Bach F W Pogrel J W | 1994 | J Neuroscience Methods1994，53，1： | 1 |
| 6 | Electrochemical sodium insertion into MnCo oxide显示文摘 | BACH S MILLET M PERIERA-RAMOS J P | 1999 | Electrochemical and Solid-State Letters1999，2，： | 1 |
| 7 | Electrochemical properties of sol-gel Li4/3 Ti5/3 O4 显示文摘 | Bach S Ramos J P Baffler N | 1999 | J Power Sources1999，8182，： | 1 |
| 8 | Suspicious cervical lymph nodes detected after thyroidectomy for papillary thyroid cancer usually remain stable over years in properly selected patients显示文摘 | Robenshtok E Fish S Bach A | 2012 | J Clin Endocrinol Metab2012，97，8： | 1 |
| 9 | Klimaokolofische auswirkungen des flugverkehres显示文摘 | Bach W Gossling S | 1996 | Geographische Rhndschau1996，48，： | 1 |
| 10 | Quantitative assessment of tactile allodynia in the rat paw显示文摘 | Chaplan S R Bach F W Pogrel J W | 1994 | J Neurosci Methods1994，53，1： | 1 |
| 11 | Quantitative assessment of tactile allodynia in the rat paw 显示文摘 | Chaplan S R Bach F W Pogrel J W | 1994 | JNeurosci Methods1994，53，1： | 1 |
| 12 | Single-Step and Multistep Mechanisms of Aromatic Nucleophilic Substitution of Halobenzenes and Halonitrobenzenes with Halide Anions: Ab Initio Computational Study Int 显示文摘 | Glukhovtsev M Bach R D Laiter S etal | 1997 | Qrg Chem1997，62，： | 1 |
| 13 | Glucose metabolism in lactating cows in response to isoenergetic infusions of propionic acid or duodenal glucose显示文摘 | LEMOSOUET S RIGOUT S BACH A | 2004 | Dairy Sci2004，87，： | 1 |
| 14 | Electrochemical properties of sol-gel Li4/3Ti5/3O4 显示文摘 | Bach S Pereira-Ramos J P Baffler N | 1999 | Journal of Power Sources1999，8182，： | 1 |
| 15 | Quantitative assessment of tactile allodynia in the rat paw显示文摘 | Chaplan S R Bach F W Pogrel J W | 1994 | J Neurosci Methods1994，53，1： | 1 |
| 16 | Glucose metabolism in lactating cows in response to isoener- getic infusions of propionic acid or duodenal glucose 显示文摘 | LEMOSQUET S RIGOUT S BACH A | 2004 | Journal of Dairy Science2004，87，6： | 1 |
| 17 | Simple MKL 显示文摘 | RAKOTOMAMONJY A BACH F CANU S GRANDVALET Y | 2008 | Machine Learnin-g Research2008，9，11： | 1 |
| 18 | Transformation of barley by microinjection into isolated zygote protoplasts显示文摘 | Preben Bach Holm Ole Olsen Martin Schnorf Henrik Brinch-Pedersen S?ren Knudsen | 2000 | Transgenic Research2000，，1： | 1 |
| 19 | Simple MKL 显示文摘 | BACH F RAKOTOMAMONJY A CANU S | 2008 | Journal of Machine Learning Research2008，9，： | 1 |
| 20 | Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IOF-II-induced proliferation and differentiation of L6AI rat myoblasts 显示文摘 | Bach L A Salerni IL Leeding K S | 1995 | Endocrinology1995，136，： | 1 |
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