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157篇 您的检索式：作者名="BECK Y"

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	题名	作者	年代	出处	被引量
1	Hematopoietic cell transplantation for Crohn’s disease;is it time?显示文摘AIM: To review all studies in the literature that have assessed Hematopoietic cell transplantation (HCT) and Crohn’s disease (CD) with the ultimate aims of determining if this is a viable treatment option for those with CD. A secondary aim was to review the above literature and determine if the studies shed further light on the mechanisms involved in the pathogenesis of CD. METHODS: An extensive Medline search was performed on all articles from 1970 to 2005 using the ; bone marrow transplant, stem cell, hematopoietic cell, Crohn’s disease and inflammatory bowel disease. RESULTS: We identified one case in which a patient developed CD following an allogeneic HCT from a sibling suffering with CD. Evidence for transfer of the genetic predisposition to develop CD was also identified with report of a patient that developed severe CD following an allogeneic HCT. Following HCT it was found that the donor (that had no signs or symptoms of CD) and the recipient had several haplotype mismatches in HLA class Ⅲ genes in the IBD3 locus including a polymorphism of NOD2/CARD15 that has been associated with CD. Thirty three published cases of patients with CD who underwent either autologous or allogeneic HCT were identified. At the time of publication 29 of these 33 patients were considered to be in remission. The median follow-up time was seven years, and twenty months for allogeneic and autologous HCT respectively.For patients who underwent HCT primarily for treatment of their CD there have been no mortalities related to transplant complications. CONCLUSION: Overall these preliminary data suggest that both allogeneic and autologous HCT may be effective in inducing remission in refractory CD. Thissupports the hypothesis that the hematolymphatic cells play a key role in CD and that resetting of the immune system may be a critical approach in the management or cure of CD.	Y Leung M Geddes J Storek R Panaccione PL Beck	2006	World Journal of Gastroenterology2006，12，41：	5
2	Strong duality in nonconvex quadratic optimization with two quadratic constraints显示文摘	Beck A Eldar Y C	2006	SIAM Journal on Optimization2006，17，3：	1
3	Chemotherapy- and radiotherapy- induced intestinal damage is regulated by intestinal trefoil factor显示文摘	Beck PL Wong JF Li Y	2004	Gastroenterology2004，126，3：	1
4	Production of 3- hydroxypropionaldehyde using a two-step process with Lactobacillus reuteri显示文摘	Doleyres Y Beck P Vollenweider S	2005	Appl Microbiol Biotechnol2005，68，：	1
5	Prolactin antagonist-endostatin fusion protein as a targeted dual-functional therapeutic agent for breast cancer显示文摘	Beck M T Chen N Y Franek K J	2003	Cancer Res2003，63，13：	1
6	Production of 3- hydroxypropionaldehyde using a two -step process with Lactobacillus reuteri 显示文摘	Doleyres Y Beck P Vollenweider S	2005	Applied Microbiology and Bioteehnology2005，，68：	1
7	Arsenic exposure and toxicology: a historical perspective 显示文摘	HUGHES M F BECK B D CHEN Y	2011	Toxicol Sci2011，132，2：	1
8	Chemotherapy - and radiotherapy - induced inteslinaldarnage is regulated by intestinal trefoil factor 显示文摘	Beck PL Wong JF Li Y	2004	Gastroenterology2004，126，3：	1
9	Glutathione peroxidase protects mice from viral-induced myocarditis 显示文摘	Beck M A Esworthy R S Ho Y S	1998	FASEB J1998，12，：	1
10	Chemotherapy-and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor显示文摘	Wong JF Li Y	2004	Gastroenterology2004，126，3：	1
11	Differential effects of dialysis and ltrafiltrate from individuals with CKD, with or without diabetes, on platelet phosphatidyl- serine extemalization显示文摘	Wang Y Beck W Deppisch R	2008	Am J Physiol Renal Physiol2008，294，1：	1
12	Three-dimensional desingularized boundary integral method for potential problem显示文摘	I Cao Y S Schults W W Beck R F	1991	International Journal for Numerical Methods in Fluids1991，12，8：	1
13	Signature fatty acids in phospholipids and lipopolysaccharides as indicators of microbial biomass and community structure in agricultural soils显示文摘	Zelles L Bai Q Y Beck T Beese F	1992	Soil Biology and Biochemistry1992，24，4：	1
14	Green's function and three-dimen- sional steady-state heat-conduction problems in a two-lay- ered composite显示文摘	Yen D H Y Beck J V	2004	Journal of Engineering Mathe Maties2004，49，3：	1
15	Strong duality in noncovex quadratic optimization with two quadratic constraints显示文摘	Beck A and Eldax Y C	2006	SIAM Journal on Optimization2006，17，3：	1
16	Processes Involved in the Site-Specific Effect of Probucol on Atherosclerosis in Apolipoprotein E Gene Knockout Mice Arterioscler显示文摘	Konstanze Beck Francoise Y	2005	Thromb Vasc Biol2005，25，：	1
17	Two types of antiprogestins have distinet effects on sitespecific phosphorylation of human progesterone receptor显示文摘	Beck CA Zhang Y Weigel NL	1996	J Biol Chem1996，271，2：	1
18	Doubly constrained robust Capon beamformer with ellipsoidal uncertainty Sets 显示文摘	Beck A Eldar Y C	2007	IEEE Transactions on Signal Processing2007，55，2：	1
19	Comparison and evaluation of methods for liver segmentation from CT datasets显示文摘	Heimann T van Ginneken B Styner MA Arzhaeva Y Aurich V Bauer C Beck A Becket C Beichel R Bekes G Bello F Binnig G Bischof H Bornik A Cashman PM Chi Y Cordova A Dawant BM Fidrich M Furst JD Furukawa D Grenacher L Hornegger J Kainmuller D Kitney RI Kobatake H Lamecker H Lange T Lee J Lennon B Li R Li S Meinzer HP Nemeth G Raicu DS Rau AM van Rikxoort EM Rousson M Rusko L Saddi KA Schmidt G Seghers D Shimizu A Slagmolen P Sorantin E Soza G Susomboon R Waite JM Wimmer A Wolf I	2009	IEEE Transactions on Medical Imaging2009，28，8：	1
20	Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae 显示文摘	Yoon Y J Beck B J Kim B S	2002	Chem Biol2002，9，2：	1

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