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| 1 | Image-based brachytherapy for cervical cancer显示文摘Cervical cancer is the third most common cancer in women worldwide; definitive radiation therapy and concurrent chemotherapy is the accepted standard of care for patients with node positive or locally advanced tumors > 4 cm. Brachytherapy is an important part of definitive radiotherapy shown to improve overall survival. While results for two-dimensional X-ray based brachytherapy have been good in terms of local control especially for early stage disease, unexplained toxicities and treatment failures remain. Improvements in brachytherapy planning have more recently paved the way for three-dimensional image-based brachytherapy with volumetric optimization which increases tumor control, reduces toxicity, and helps predict outcomes.Advantages of image-based brachytherapy include:improved tumor coverage(especially for large volume disease), decreased dose to critical organs(especially for small cervix), confirmation of applicator placement, and accounting for sigmoid colon dose. A number of modalities for image-based brachytherapy have emerged including: magnetic resonance imaging(MRI),computed tomography(CT), CT-MRI hybrid, and ultrasound with respective benefits and outcomes data. Forpractical application of image-based brachytherapy the Groupe Europeen de Curietherapie-European Society for Therapeutic Radiology and Oncology Working Group and American Brachytherapy Society working group guideline serve as invaluable tools, additionally here-in we outline our institutional clinical integration of these guidelines. While the body of literature supporting image-based brachytherapy continues to evolve a number of uncertainties and challenges remain including: applicator reconstruction, increasing resource/cost demands, mobile four-dimensional targets and organs-at-risk, and accurate contouring of 'grey zones' to avoid marginal miss. Ongoing studies, including the prospective EMBRACE(an international study of MRI-guided brachytherapy in locally advanced cervical cancer) trial, along with continued improvements in imaging, contouring, quality assurance, physics, and brachytherapy delivery promise to perpetuate the advancement of image-based brachytherapy to optimize outcomes for cervical cancer patients. | John A Vargo Sushil Beriwal | 2014 | World Journal of Clinical Oncology2014，5，5： | 7 |
| 2 | Five year prostate-specific antigen outcomes after caesium prostate brachytherapy显示文摘 | BenoitRM SmithRP BeriwalS | 2014 | Clin Oncol (R Coll Radiol)2014，26，12： | 1 |
| 3 | Does the number of nodes removed impact survival in vulvar cancer patients with node-negative disease 显示文摘 | Courtney-Brooks M Sukumvanich P Beriwal S | 2010 | Gynecol Oncol2010，117，2： | 1 |
| 4 | Loop - mediated isothermal amplification assay for rapid detection of conunon strains of Escherichia coli 显示文摘 | Hill J Beriwal S Chandra I | 2008 | J Clin Microbiol2008，46，8： | 1 |
| 5 | High-dose-rate interstitial computed tomography-hased hrachytherapy for the treatment of cer- vical cancer : early results 显示文摘 | Kannan N Beriwal S Kim H | 2012 | Brachytberapy2012，11，5： | 1 |
| 6 | Loop-mediated isothermal ampli? cation assay for rapid detection of common strains of Escherichia coli显示文摘 | HILL J BERIWAL S CHANDRA I | | 0，，08： | 1 |
| 7 | Intensity-modulated radiothera- py for the treatment of vulvar carcinoma: a comparative dosimetric study with early clinical outcome 显示文摘 | Beriwal S Heron DE Kim H | 2006 | Int J Radiat Oncol Biol Phys2006，64，5： | 1 |
| 8 | Clinical outcome withadjuvant treatment of endometrial carcinoma using intensity-modulated radiation therapy 显示文摘 | Beriwal S Jain SK Heron De | 2006 | Gynecol Oncol2006，102，2： | 1 |
| 9 | Loop-mediated isothermal ampli- fication assay for rapid detection of common strains of Escherichia coli 显示文摘 | Hill J Beriwal S Chandra I | 2008 | J Clin Microbiol2008，46，8： | 1 |
| 10 | Breast -conserving therapy after neoadjuvant chemotherapy:long-term results显示文摘 | Beriwal S Schwartz GF Komarnicky L | 2006 | The Breast Journal2006，12，2： | 1 |
| 11 | High-dose rate interstitial brachytherapy for gynecologic malignancies 显示文摘 | Beriwal S Bhatnagar A Heron DE | 2006 | Brachytherapy2006，5，4： | 1 |
| 12 | CK5 is more sensitive than CK5/6 in identifying the 'basal-like' phcnotype of breast carcinoma 显示文摘 | Bhargava R Beriwal S MeManus K | 2008 | Am J Clin Pathol2008，130，5： | 1 |
| 13 | The intrafraction motion induced dosimetric impacts in breast 3D radiation treatment:a 4DCT based study显示文摘 | Yue N J Li X Beriwal S | 2007 | Med Phys2007，34，： | 1 |
| 14 | High-dose-rate interstitial computed tomography-based brachytherapy for the treatment of cervical cancer:early results显示文摘 | Kannan N Beriwal S Kim H | | 0，，05： | 1 |
| 15 | Breast-conserving therapy after neoadjuvant chemotherapy : long-term results 显示文摘 | Beriwal S Schwartz GF Komarnicky L | 2006 | Breast J2006，12，2： | 1 |
| 16 | Loop-mediated isothermal am- plification assay for rapid detection of common strains of Escherichia coli显示文摘 | Hill J Beriwal S Chandra I | 2008 | J Clin Microbiol2008，46，8： | 1 |
| 17 | Possible use of CA-125 level normalization after the third chemotherapy cycle in deciding on chemotherapy regimen in patients with epithelial ovarian cancer,brief report显示文摘 | Skaznik-Wikiel ME Sukumvanich P Beriwal S | 2011 | Int J Gynecol Cancer2011，21，6： | 1 |
| 18 | Three-dimensional high dose rate intracavitary image-guided brachytherapy for the treatment of cervical cancer using a hybrid magnetic resonance imaging/ computed tomography approach:feasibility and early results显示文摘 | Beriwal S Kannan N Kim H | 2011 | Clin Oncol2011，23，10： | 1 |
| 19 | Predicting Likelihood of Having Four or More Positive Nodes in Patient with Sentinel Lymph Node-Positive Breast Cancer: A Nomogram Validation Study显示文摘 | Unal B Gur AS Beriwal S | 2009 | Int J Radiat Oncol Biol Phys2009，，： | 1 |
| 20 | Breast-conserving thera- py after neoadjuvant chemotherapy:long-term results 显示文摘 | Beriwal S Schwartz GF Komarnicky L | 2006 | Breast J2006，12，2： | 1 |
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