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| 1 | Rare complications of pediatric diabetic ketoacidosis显示文摘The incidence of type 1 diabetes(T1D) among youth is steadily increasing across the world. Up to a third of pediatric patients with T1 D present with diabetic ketoacidosis, a diagnosis that continues to be the leading cause of death in this population. Cerebral edema is the most common rare complication of diabetic ketoacidosis in children. Accordingly, treatment and outcome measures of cerebral edema are vastly researched and the pathophysiology is recently the subject of much debate. Nevertheless, cerebral edema is not the onlysequela of diabetic ketoacidosis that warrants close monitoring. The medical literature details various other complications in children with diabetic ketoacidosis, including hypercoagulability leading to stroke and deep vein thrombosis, rhabdomyolysis, pulmonary and gastrointestinal complications, and long-term memory dysfunction. We review the pathophysiology, reported cases, management, and outcomes of each of these rare complications in children. As the incidence of T1 D continues to rise, practitioners will care for an increasing number of pediatric patients with diabetic ketoacidosis and should be aware of the various systems that may be affected in both the acute and chronic setting. | Shara R Bialo Sungeeta Agrawal Charlotte M Boney Jose Bernardo Quintos | 2015 | World Journal of Diabetes2015，6，1： | 9 |
| 2 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 3 | Lessons from the ( ' Iressa' expanded access programme: Gefitinib in special non-small-cell lung cancer patient populations 显示文摘 | Stahel R Rossi A Petruzelka L Kosimidis P de Braud F Bernardo MM | 2003 | Br J Cancer2003，89，2： | 1 |
| 4 | Plastic rotation ca- pacity of high-strength concret beams 显示文摘 | Lopes S M R Bernardo L F A | 2003 | Materials and Structure/Materiaux et Constructions2003，36，225： | 1 |
| 5 | Chromosomal regions associated with segregation distortion in maize 显示文摘 | Lu H Romero Severson J Bernardo R | 2002 | Theoreti cal and Applied Genetics2002，105，62： | 1 |
| 6 | Chromosomal regions associated with segregation distortion in maize显示文摘 | Lu H Romero severson J Bernardo R | 2002 | Theoretical and Applied Genetics2002，105，： | 1 |
| 7 | RFLP-based estimates of parental contribution to F2- and BCi_ de-rived maize inbreds 显示文摘 | Bernardo R Murigneux A Maisonneuve J P | 1997 | Theoretical and Applied Genetics1997，94，： | 1 |
| 8 | Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease显示文摘 | Ciccocioppo R Bernardo ME Sgarella A | 2011 | Gut2011，60，6： | 1 |
| 9 | β subunits influence the biophysical and pharmacological differences between P- and Q-type calcium currents expressed in a mammalian cell line 显示文摘 | Herman M Bernardo R Rodolfo L | 1997 | Proc Natl Acad Sci USA1997，94，14： | 1 |
| 10 | The impact of knowledge about diabetes, resilience and de- pression on glyeemic control: a cross-sectional study among adolescents and young adults with type 1 diabetes显示文摘 | SANTOS F R BERNARDO V GABBAY M A | 2013 | Di- abetol Metab Syndr2013，5，1： | 1 |
| 11 | In silico mapping of quantitative trait loci in maize显示文摘 | Parisseaux B Bernardo R | 2004 | Theor Appl Genet2004，109，3： | 1 |
| 12 | Molecular marker diversity among current and historical maize inbreds显示文摘 | Lu H Bernardo R | 2001 | Theoretical Applied Genetics2001，103，： | 1 |
| 13 | Usefulness of gene information in mark- er-assistod recurrent selection : Asimulation appraisal 显示文摘 | Bernardo R Charoosset A | 2006 | Crop Sei2006，46，： | 1 |
| 14 | Parental contribution and coefficient of ancestry among maize inbreds:Pedigree,RFLP,and SSR data显示文摘 | Bernardo R Romero-Severson J Ziegle J Hauser J Joe L HookStra G Diverge R W | 2000 | Theoretical and Applied Genetics2000，100，： | 1 |
| 15 | A tutorial on EMPA: A theory of concurrent processes with nondeterminism, priorities, probabilities and time 显示文摘 | Bernardo M Gorrieri R | 1998 | Theoretical Computer Science1998，202，12： | 1 |
| 16 | Molecular markers and selection for complex traits in plants: Learning from the last 20 years 显示文摘 | Bernardo R | 2008 | Crop Science2008，48，： | 1 |
| 17 | Chromosomal regions associated With segregation distortion in maize 显示文摘 | LU H ROMEROR SEVERSON J BERNARDO R | 2002 | Theor Appl Genet2002，105，： | 1 |
| 18 | Purification,characterization,and biosynthesis of human acid ceramidase显示文摘 | Bernardo K Hurwitz R Zenk T | 1995 | J Biol Chem1995，270，11： | 1 |
| 19 | Characterization and supercritical carbon dioxide extraction of walnut oil 显示文摘 | Oliveira R Rodrigues MF Bernardo - Gil MG | 2002 | Journal of the American Oil Chemists''s Society2002，79，3： | 1 |
| 20 | Oxidative stress, renal infiltration of immune cells, and salt- sensitive hypertension: All for one and one for all 显示文摘 | BERNARDO R I NOSRATOLA D V JAIME H A | 2004 | Am J Physiol Renal Physiol2004，286，： | 1 |
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