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| 1 | Mixers with Microstructured Foils for Chemical Production Purposes显示文摘约翰威立出版公司是世界知名的出版集团,出版、发行许多著名学术、技术期刊和书籍。《化工进展》编辑部从2005年第5期起,与新加坡约翰威立股份有限公司合作,不定期刊登其出版、发行的知名化工期刊的原版文章。欢迎读者提出宝贵意见。 | Bernd Werner Volker Hessel Patrick Lb | 2005 | 化工进展2005，24，5： | 3 |
| 2 | Parameters of a severe disease course in ulcerative colitis显示文摘AIM:To detect high risk patients with a progressive disease course of ulcerative colitis(UC) requiring immunosuppressive therapy(IT).METHODS:A retrospective,multicenter analysis of 262 UC patients from eight German tertiary inflammatory bowel disease centres was performed.Patients were divided into two groups depending on the patients need to initiate immunosuppressive therapy in the disease course.A comparison between the two groups was made with regard to demographics,clinical and laboratory parameters obtained within three months after UC diagnosis and the response to first medical therapy.Using this data,a prognostic model was established to predict the individual patients probability of requiring an immunosuppressive therapy.RESULTS:In 104(39.7%) out of 262 patients,UC therapy required an immunosuppressive treatment.Patients in this group were significantly younger at time of diagnosis(HR = 0.981 ± 0.014 per year,P = 0.009),and required significantly more often a hospitalisation(HR = 2.5 ± 1.0,P < 0.001) and a systemic corticosteroid therapy at disease onset(HR = 2.4 ± 0.8,P < 0.001),respectively.Response to steroid treatment was significantly different between the two groups of patients(HR = 5.2 ± 3.9 to 50.8 ± 35.6 compared to no steroids,P = 0.016 to P < 0.001).Furthermore,in the IT group an extended disease(HR = 3.5 ± 2.4 to 6.1 ± 4.0 compared to proctitis,P = 0.007 to P = 0.001),anemia(HR = 2.2 ± 0.8,P < 0.001),thrombocytosis(HR = 1.9 ± 1.8,P = 0.009),elevated C-reactive protein(CRP)(HR = 2.1 ± 0.9,P < 0.001),and extraintestinal manifestations in the course of disease(HR = 2.6 ± 1.1,P = 0.004) were observed.Six simple clinical items were used to establish a prognostic model to predict the individual risk requiring an IT.This probability ranges from less than 2% up to 100% after 5 years.Using this,the necessity of an immunosuppressive therapy can be predicted in 60% of patients.Our model can determine the need for an immunosuppressive drug therapy or if a 'watch and wait' approach is reasonable already early in the treatment course of UC.CONCLUSION:Using six simple clinical parameters,we can estimate the patients individual risk of developing a progressive disease course. | Andreas Stallmach Luisa Nickel Thomas Lehmann Bernd Bokemeyer Martin Bürger Dietrich Hüppe Wolfgang Kruis Susanna Nikolaus Jan C Preiss Andreas Sturm Niels Teich Carsten Schmidt | 2014 | World Journal of Gastroenterology2014，20，35： | 2 |
| 3 | Progress in evaluation of risk potential of ionic liquids--basis for all eco-design of sustainable products显示文摘 | BERND J KERSTIN M PETER B | 2005 | Green Chem2005，7，： | 1 |
| 4 | A thermal model for high speed motorized spindles显示文摘 | JAY F T | 1999 | International Journal of Machine Tools & Manufacture1999，39，： | 1 |
| 5 | Plasma exchange as rescue therapy in multiple organ failure including acute renal failure显示文摘 | Bernd GS Ravjet B Lars B | 2003 | Crit Care Med2003，31，： | 1 |
| 6 | The prospects for willow plantations for wastewater treatment in Sweden显示文摘 | B?rjesson P Berndes G | | 0，，： | 1 |
| 7 | Additive manuthcturing for microvascular reconstruction of the mandible in 20 patients显示文摘 | Bernd Lethaus Lucas Poort Roland B? ckmann | 2012 | Journal of Cranio-Maxilloihcial Surgery2012，40，1： | 1 |
| 8 | Permutation entropy, a natural complexity measure for time series 显示文摘 | CHRISTOPH B BERND P | 2002 | Physical Review Letters2002，88，17： | 1 |
| 9 | Traffic noise and risk of myocardial infarction 显示文摘 | Wolfgang B Bernd B Marianne S | 2005 | Epidemiology2005，16，1： | 1 |
| 10 | Topoisomerase degradation,DSB repair,p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase Ⅰ inhibitors显示文摘 | Tomicic M T Bernd K B | 2013 | Biochimica et Biophysica Acta2013，1835，： | 1 |
| 11 | Permutation entropy:a natural complexity measure for time series显示文摘 | CHRISTOPH B BERND P | 2002 | Physical Review Letters2002，88，17： | 1 |
| 12 | Modeling the adsorption of metal-EDTA complexes onto oxides 显示文摘 | BERND N JOHANNES L PHILIPPE B | 1996 | Environmental Science & Technology1996，30，： | 1 |
| 13 | Traffic noise andrisk of myocardial infarction显示文摘 | Wolfgang B Bernd B Marianne S | 2005 | Epidemiology2005，，1： | 1 |
| 14 | Cerebral resuscitation potentials for cardiac arrest显示文摘 | Safar P Behringer W Bernd W B | 2002 | Crit Care Med2002，30，4： | 1 |
| 15 | Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinaseγ显示文摘 | Philipp V Carsten B Bernd N | 2005 | Biol Chem2005，280，6： | 1 |
| 16 | Pb isotopes in sediments of Lake Constance,Central Europe constrain the heavy metal pathways and the pollution history of the catchment,the lake and the regional atmosphere显示文摘 | BERND K MARTIN W ANDREAS B | 1999 | Geochimica et Cosmochimica Acta1999，63，9： | 1 |
| 17 | Crowdsourcing, citizen sensing and sensor Web technologies for public and envi- ronmental health surveillance and crisis management: trends, OGC standards and application examples 显示文摘 | KAkIEL B BERND R DAVID N C | 2011 | International Journal of Health Geographics2011，，10： | 1 |
| 18 | CT of coronary artery disease显示文摘 | Joseph S Christoph B Bernd O | 2004 | Radiology2004，232，1： | 1 |
| 19 | Neural networks for multiuser detection in code-division multiple-access communications显示文摘 | Bernd P P Orsak G | 1992 | IEEE Trans on Commun1992，40，： | 1 |
| 20 | Self-assembly and characterization of mesostructured silica films with a 3D arrangement of isolated spherical mesopores显示文摘 | Yu K Bernd S Jeffrey B | 2003 | Adv Funct Mater2003，13，1： | 1 |
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