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| 1 | Geochronology and significance of volcanic rocks in the Ning-Wu Basin of China显示文摘The Ning-Wu(Nanjing-Wuhu) Basin is one of the most important volcanic basins in the Middle-Lower Yangtze River Valley,eastern China.It consists of four volcanic units,i.e.,the Longwangshan,Dawangshan,Gushan,and Niangniangshan Formations.Their LA-ICP MS U-Pb zircon ages are 134.8±1.8,132.2±1.6,129.5±0.8,and 126.8±0.6 Ma,respectively.Results of this study indicate that all volcanic rocks in the Ning-Wu Basin were formed in the Early Cretaceous from 135 to 127 Ma,lasting 8-10 m.y.No Jurassic volcanic activities occurred in any of the volcanic basins of the Middle-Lower Yangtze River Valley,including the Ning-Wu Basin.These new chronological results provide significant evidence for further study of this region to improve our understanding of Mesozoic tectonic,magmatic,and metallogenic processes of eastern China. | ZHOU TaoFa FAN Yu YUAN Feng ZHANG LeJun QIAN Bin MA Liang YANG XiFei David R COOKE | 2011 | Science China Earth Sciences2011，54，2： | 33 |
| 2 | 5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages显示文摘5-Hydroxymethylcytosine (5hmC ) 是被连接了到基因规定和癌症致病的重要哺乳动物的 DNA epigenetic 修正。这里,我们用定序途径的一枝敏感化学基于标签的低输入的猎枪在传播没有房间的 DNA (cfDNA ) 探索了 5hmC 的诊断潜力。我们从七种不同癌症类型的 49 个病人定序没有房间的 5hmC 并且发现了能被用来与高精确性预言癌症类型和阶段的不同特征。明确地,我们发现肺癌症在 cfDNA 导致 5hmC 的进步全球损失,而 hepatocellular 癌和胰腺的癌症在没有房间的 hydroxymethylome 导致疾病特定的变化。我们的 proof-of-principle 结果建议没有房间的 5hmC 签名可以潜在地被使用不仅识别癌症类型而且在一些癌症追踪肿瘤舞台。 | Chun-Xiao Song Senlin Yin Li Ma Amanda Wheeler Yu Chen Yan Zhang Bin Liu Junjie Xiong Weihan Zhang Jiankun Hu Zongguang Zhou Biao Dong Zhiqi Tian Stefanie S Jeffrey Mei-Sze Chua Samuel So Weimin Li Yuquan Wei Jiajie Diao Dan Xie Stephen R Quake | 2017 | Cell Research2017，27，10： | 17 |
| 3 | Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins(BMPs)in lineage commitment and differentiation of mesenchymal stem cells(MSCs)显示文摘Mesenchymal stem cells(MSCs)are ubiquitously-existing multipotent progenitors that can self-renew and differentiate into multiple lineages including osteocytes,chondrocytes,adipocytes,tenocytes and myocytes.MSCs represent one of the most commonly-used adult progenitors and serve as excellent progenitor cell models for investigating lineagespecific differentiation regulated by various cellular signaling pathways,such as bone morphogenetic proteins(BMPs).As members of TGFb superfamily,BMPs play diverse and important roles in development and adult tissues.At least 14 BMPs have been identified in mammals.Different BMPs exert distinct but overlapping biological functions.Through a comprehensive analysis of 14 BMPs in MSCs,we demonstrated that BMP9 is one of the most potent BMPs in inducing osteogenic differentiation of MSCs.Nonetheless,a global mechanistic view of BMP signaling in regulating the proliferation and differentiation of MSCs remains to be fully elucidated.Here,we conducted a comprehensive transcriptomic profiling in the MSCs stimulated by 14 types of BMPs.Hierarchical clustering analysis classifies 14 BMPs into three subclusters:an osteo/chondrogenic/adipogenic cluster,a tenogenic cluster,and BMP3 cluster.We also demonstrate that six BMPs(e.g.,BMP2,BMP3,BMP4,BMP7,BMP8,and BMP9)can induce ISmads effectively,while BMP2,BMP3,BMP4,BMP7,and BMP11 up-regulate Smad-independent MAP kinase pathway.Furthermore,we show that many BMPs can upregulate the expression of the signal mediators of Wnt,Notch and PI3K/AKT/mTOR pathways.While the reported transcriptomic changes need to be further validated,our expression profiling represents the first-of-its-kind to interrogate a comprehensive transcriptomic landscape regulated by the 14 types of BMPs in MSCs. | Linghuan Zhang Qing Luo Yi Shu Zongyue Zeng Bo Huang Yixiao Feng Bo Zhang Xi Wang Yan Lei Zhenyu Ye Ling Zhao Daigui Cao Lijuan Yang Xian Chen Bin Liu William Wagstaff Russell R*Reid Hue H*Luu Rex C*Haydon Michael J*Lee Jennifer Moriatis Wolf Zhou Fu Tong-Chuan He Quan Kang | 2019 | Genes & Diseases2019，6，3： | 11 |
| 4 | Observations of the Karimata Strait througflow from December 2007 to November 2008显示文摘In order to quantitatively estimate the volume and property transports between the South China Sea and Indonesian Seas via the Karimata Strait, two trawl-resistant bottom mounts, with ADCPs embedded, were deployed in the strait to measure the velocity profile as part of the South China Sea-Indonesian Seas transport/exchange (SITE) program. A pair of surface and bottom acoustic modems was employed to transfer the measured velocity without recovering the mooring. The advantage and problems of the instruments in this field work are reported and discussed. The field observations confirm the existence of the South China Sea branch of Indonesian throughflow via the Karimata Strait with a stronger southward flow in boreal winter and weaker southward bottom flow in boreal summer, beneath the upper layer northward (reversal) flow. The estimate of the averaged volume, heat and freshwater transports from December 2007 to March 2008 (winter) is (-2.7 ± 1.1) × 10 6 m3/s, (-0.30 ± 0.11) PW, (-0.18 ± 0.07) × 106m3/s and from May to September 2008 (summer) is (1.2 ± 0.6) × 106m3/s, (0.14 ± 0.03) PW, (0.12 ± 0.04) × 106m3/s and for the entire record from December 2007 to October 2008 is (-0.5 ± 1.9) × 10 6 m3/s, (-0.05 ± 0.22) PW, (-0.01 ± 0.15) × 106m3/s (negative/positive represents southward/northward transport), respectively. The existence of southward bottom flow in boreal summer implies that the downward sea surface slope from north to south as found by Fang et al. (2010) for winter is a year-round phenomenon. | SUSANTO R Dwi WEI Zexun ADI Rameyo T FAN Bin LI Shujiang FANG Guohong | 2013 | Acta Oceanologica Sinica2013，32，5： | 9 |
| 5 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 6 | Wave interaction with a new type perforated breakwater显示文摘在这,检验的学习是和新修改穿孔防波提的波浪相互作用,由与一个二层的充满岩石的核心吸收在他们之间的房间的一面穿孔前面墙,一面稳固的背墙和一个波浪组成。液体领域根据防波提的部件被划分成三子域。然后借助于匹配的特徵函数扩大方法,一个分析解决方案被获得估计新结构的水动力学性能。一条途径基于一个步途径方法被介绍在二层的多孔的媒介以内为水波浪运动解决复杂分散方程。现在的模型的数字结果与以前的限制盒子相比。岩石的效果在思考系数上充满,水平波浪力量被讨论。 | Yong Liu Yucheng Li Bin Teng State Key Laboratory of Coastal and Offshore Engineering.Dalian University of Technology,Dalian 116024,China R&D Center for Civil Engineering Technology,Dalian University,Dalian 116622,China | 2007 | Acta Mechanica Sinica2007，23，4： | 4 |
| 7 | Nonadiabatic acceleration of plasma sheet ions related to ion cyclotron waves显示文摘The nonadiabatic acceleration of plasma sheet ions is important to the understanding of substorm energetic injections and the formation of ring current. Previous studies show that nonadiabatic acceleration of protons by magnetic field dipolarization is hard to occur at X>–10 RE because the time-scale of dipolarization(several minutes) is much larger than the gyroperiod of protons there(several seconds). In this paper, we present a case of nonadiabatic acceleration of plasma sheet ions observed by Cluster on October 30, 2006 at(XGSM, YGSM)=(-7.7, 4.7) RE. The nonadiabatic acceleration of ions is caused not by previously reported magnetospheric dipolarization but by the ultra low frequency(ULF) waves during magnetospheric dipolarization. The nonadiabatic acceleration of ions generates a new energy flux structure of ions, which is characterized by the usual energy flux increase of ions(28–80 ke V) and a concurrent energy flux decrease of ions in a lower energy range(10 e V–20 ke V). These new observations constitute a complete physical picture: The lower energy ions absorb the wave energy, and thus get accelerated to higher energy. We use a nonadiabatic model to interpret the ion energy flux variations. Both analytic and simulation results are in good agreement with the observations. This indicates that the nonadiabatic acceleration associated with ULF waves superposed on dipolarized magnetic field is an effective mechanism for ion energization in the near-Earth plasma sheet. The presented energy flux structures can be used as a proxy to identify the similar dynamic process. | WANG Zhi Qiang CAO Jin Bin RME Henri DANDOURAS Iannis MA Yu Duan | 2014 | Science China(Technological Sciences)2014，57，12： | 3 |
| 8 | Comparison Between AFLP and RFLP Markers in Detecting the Diversity of Rice(Oryza sativa L.)显示文摘AFLP and RFLP were used to study the diversity of 20 rice cultivars. 15 primer combinations were used in the AFLP analysis and 47 - 118 bands were amplified in each lane. A total of 107 polymorphic bands were detected in the RFLP analysis using 49 RFLP probes. The cluster analysis based on RFLP data showed that 20 rice cultivars could be divided into an indica group and a japonica group, as did the AFLP data; however AFLP is more suitable in detecting the difference of pedigree and ecotype among the 20 cultivars.The genetic distance based on AFLP and RFLP data showed the same tendency, but AFLP markers increased the measure of genetic distance among intra-subspecific cultivars and decreased the measure of genetic distance among inter-subspecific cultivars relative to RFLP markers. That indicated that AFLP is more suitable than RFLP in the diversity study and RFLP is more suitable to study the indica-japonica differentiation of cultivars. | CHEN Liang, LIANG Chun-yang, SUN Chuan-qing, JIN De-min, JIANG Ting-bo, WANG Bin and WANG Xiang-kun( China Agricultural University, Beijing 100094 , P. R . China Institute of Genetics and Developmental Biology, Chinese Academy of Science , Beijing 100101, P.R.China) | 2002 | Agricultural Sciences in China2002，1，7： | 2 |
| 9 | Removal of arsenic by magnetic biochar prepared from pinewood and natural hematite显示文摘 | Shengsen Wang Bin Gao Andrew R Zimmerman Yuncong Li Lena Ma Willie Harris Kati Migliaccio | 2014 | Bioresource Technology2014，，： | 2 |
| 10 | A novel power factor control scheme for high-power GTO current-source converter显示文摘 | Xiao Yuan Wu Bin Steven C R | 1998 | IEEE Transactions on Industry Applications1998，34，6： | 1 |
| 11 | A new technique for measuring the mechanical properties of thin films 显示文摘 | Shape W N Bin Y Edwards R L | 1997 | Journal of Microelectromech System1997，，6： | 1 |
| 12 | An integrated approach to high-level information fusion显示文摘 | Sycera K Glinton R Yu Bin | | 0，，01： | 1 |
| 13 | Structural graph matching using the EM algorithm and singular value decomposition显示文摘 | LUO Bin HANCOCK E R | 2001 | IEEE Trans on Pattern Analysis and Machine Intelligence2001，23，10： | 1 |
| 14 | Heterogeneous Nitrification in a Full-Scale Rapid Sand Filter Treating Groundwater显示文摘 | Lopato L R?ttgers N Binning P J | 2013 | Journal of Environmental Engineering2013，139，3： | 1 |
| 15 | A multilevel thyristor rec- tifier with improved power factor显示文摘 | ZARGARI N R XIAO Yuan WU Bin | 1997 | IEEE Transactions on Indus- try Applications1997，33，5： | 1 |
| 16 | Powder injection molding and infiltration sintering of superfine grain W-Cu显示文摘 | GERMAN R M | 1997 | International Journal of Powder Metallurgy1997，33，4： | 1 |
| 17 | A preliminary study of the dermal absorption of aluminium from antiperspirants using aluminium-26 显示文摘 | FLAREND R BIN T ELMORE D | 2001 | Food Chem Toxicol2001，39，2： | 1 |
| 18 | Associationbetween plasma levels of heat shock protein 60 and cardiovasculardisease in patients with diabetes mellitus显示文摘 | SHAMAEI TOUSI A STEPHENS J BIN R | 2006 | Eur Heart J2006，27，13： | 1 |
| 19 | Drying of pear d' Anjou with and without osmotic dehydration 显示文摘 | PARK K J BIN A BROD F P R | 2002 | Journal of Food Engineering2002，56，1： | 1 |
| 20 | Identification of novel gene signa- tures in patients with atopic dermatitis complicated by eczema herpetic- um 显示文摘 | Bin L Edwards MG Heiser R | 2014 | J Allergy Clin Immuno12014，134，4： | 1 |
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