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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis显示文摘 | Phil A Hart Terumi Kamisawa William R Brugge Jae Bock Chung Emma L Culver László Czakó Luca Frulloni Vay Liang W Go Thomas M Gress Myung-Hwan Kim Shigeyuki Kawa Kyu Taek Lee Markus M Lerch Wei-Chih Liao Matthias L?hr Kazuichi Okazaki Ji Kon Ryu Nicolas Sc | 2013 | Gut2013，，12： | 2 |
| 3 | OrganellarGenomeDRAW (OGDRAW): A tool for the easy generation of highquality custom graphical maps of plastid and mitochondrial genomes显示文摘 | Lohse M Drechsel O Bock R 2007 | 2007 | Current Genetics2007，52，： | 1 |
| 4 | Behavioral intention formation in knowledge sharing:Examining the roles of extrinsic motivators,social-psychological forces,and organizational chmate显示文摘 | Bock G W Zmud R W Kim Y G Lee J N | | 0，，01： | 1 |
| 5 | Behavioral In tention Formation in Knowledge Sharing: Exami ning the Roles of Extrinsic Motlvatiors, Social-Psy chological Forces, and Organizational Climate 显示文摘 | BOCK G ZMUD R KIM Y | 2005 | MIS Quarterly2005，29，1： | 1 |
| 6 | Taming plastids for a green future显示文摘 | Bock R Khan M S | 2004 | Trends Biotechnology2004，22，： | 1 |
| 7 | Carbon aerogels as electrode material in supercapacitors显示文摘 | FISCHER U SALIGER R BOCK V | 1997 | J Porous Materials1997，4，： | 1 |
| 8 | Comparison of caudal and intravenous clonidine in the prevention of agitation after sevoflurane in children 显示文摘 | Bock M Kunz P Chreckenberger R | 2002 | Br J Anaesthesia2002，88，6： | 1 |
| 9 | Microanalysis of museum aerosols to elucidate the soiling of paintings: Case of the Correr Museum, Venice, Italy显示文摘 | De Bock L A van Grieken R E Camuffo D | 1996 | Environmental Science & Technology1996，30，11： | 1 |
| 10 | Synthesis and Biological Evaluation of a ^99Tc^m-Labelied Cyclic RGD Peptide for Imaging αvβ3 Expression显示文摘 | Haubner R Brucheritseifer M Bock M | 2004 | Nuklearmedizin2004，43，： | 1 |
| 11 | Tissue- and stage-specific modulation of RNA editing of the psbF and psbL transcript from spinach plastids-a new regulatory mechanism?显示文摘 | Bock R Hagemann R K?ssel H Kudla J | 1993 | Mol Gen Genet1993，240，2： | 1 |
| 12 | Microanalysis of museum aerosols to elucidate the soiling of paintings: case of the Correr Museum, Venice, Italy显示文摘 | De Bock L A Grieken R E V Camuffo D | 1996 | Envir Sci Technol1996，30，： | 1 |
| 13 | Sensitive and specific detection of proviral bovine leukemia virus by 5' Taq nuclease PCR using a 3' minor groove binder fluorogenic probe 显示文摘 | Lew A E Bock R E Molloy J B | 2004 | J Virol Methods2004，115，2： | 1 |
| 14 | Behavioral intention formation in knowledge sharing: examining the roles of extrinsic motivators, social - psychological forces, and organizational climate 显示文摘 | BOCK GEE -WOO ZMUD R W KIM YOUNG- GUL | 2005 | MISQuarterly2005，29，1： | 1 |
| 15 | Gas-Phase Pyrolysis of Aikyl Azides: Expremental Evideunce for Chemical Activation显示文摘 | DAMMEL R | 1988 | J Am Chem Sos1988，110，： | 1 |
| 16 | Molecular farming for new drugs and vaccines-Current perspectives on the production of pharmaceuticals in transgenic plants显示文摘 | Ma J K C Barros E Bock R | 2005 | EMBO Rep2005，6，7： | 1 |
| 17 | Comparison of caudal and intravenous elonidine in the prevention of agitation after sevoflurane in children显示文摘 | Bock M Kunz P Schreckenberger R | 2002 | Br J Anaesth2002，88，6： | 1 |
| 18 | Nitrogen loss caused by denitrifying Nitrosomonas cells using ammonia or hydrogen as electron donors and nitrite as electron acceptor显示文摘 | Bock E Schmidt 1 Stuven R | 1995 | Arch Microbiol1995，163，： | 1 |
| 19 | Behavioral intention formation in knowledge sharing: Examining the roles of extrinsic motivators, social - psychological forces, and organizational climate 显示文摘 | Bock G W Zmud R W Kim Y G | 2005 | M1S Quarterly2005，29，1： | 1 |
| 20 | Global DNA dem-ethylation during mouse erythropoiesis in vivo 显示文摘 | Shearstone JR Pop R Bock C | 2011 | Sci-ence2011，334，： | 1 |
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