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| 1 | 川东北地区构造-热演化探讨--来自(U-Th)/He年龄和Ro的约束显示文摘利用镜质组反射率和磷灰石与锆石的(U-Th)/He年龄一起模拟了川东北地区三叠纪以来的构造-热演化特征。结果表明早三叠世的热流值在51~66mW/m2,自晚三叠世至白垩纪随盆地性质由前陆盆地演化为陆内坳陷盆地,热流缓慢降低直至现今的44.5mW/m2。但在晚白垩世—古新世时期受燕山晚期构造运动的影响,热流有一个微弱增高的现象。同时,磷灰石和锆石的He年龄揭示了川东北地区大致在晚白垩世期间开始隆升且抬升剥蚀量较大。因此,磷灰石和锆石的(U-Th)/He年龄可以揭示后期详细的冷却历史。 | 邱楠生 秦建中 Brent I A Mclnnes 王杰 腾格尔 郑伦举 | 2008 | 高校地质学报2008,14,2: | 59 |
| 2 | Sphingosine-1-phosphate signaling in vasculogenesis and angiogenesis显示文摘Blood vessels either form de novo through the process of vasculogenesis or through angiogenesis that involves the sprouting and proliferation of endothelial cells in pre-existing blood vessels. A complex interactive network of signaling cascades downstream from at least three of the nine known G-protein-coupled sphingosine-1-phosphate (S1P) receptors act as a prime effector of neovascularization that occurs in embryonic development and in association with various pathologies. This review focuses on the current knowledge of the roles of S1P signaling in vasculogenesis and angiogenesis, with particular emphasis on vascular cell adhesion and motility responses. | Kelley M Argraves Brent A Wilkerson W Scott Argraves | 2010 | World Journal of Biological Chemistry2010,1,10: | 6 |
| 3 | Systematic review and meta-analysis on the association of tuberculosis in Crohn's disease patients treated with tumor necrosis factor-α inhibitors(Anti-TNFα)显示文摘AIM To perform a meta-analysis on the risk of developing Mycobacterium tuberculosis(TB) infection in Crohn's disease(CD) patients treated with tumor necrosis factoralpha(TNFα) inhibitors.METHODS A meta-analysis of randomized, double-blind, placebocontrolled trials of TNFα inhibitors for treatment of CD in adults was conducted. Arcsine transformation of TB incidence was performed to estimate risk difference. A novel epidemiologically-based correction(EBC) enabling inclusions of studies reporting no TB infection cases in placebo and treatment groups was developed to estimate relative odds.RESULTS Twenty-three clinical trial studies were identified, including 5669 patients. Six TB infection cases were reported across 5 studies, all from patients receiving TNFα inhibitors. Eighteen studies reported no TB infection cases in placebo and TNFα inhibitor treatment arms. TB infection risk was significantly increased among patients receiving TNFα inhibitors, with a risk difference of 0.028(95%CI: 0.0011-0.055). The odds ratio was 4.85(95%CI: 1.02-22.99) with EBC and 5.85(95%CI: 1.13-30.38) without EBC.CONCLUSION The risk of TB infection is higher among CD patients receiving TNFα inhibitors. Understanding the immunopathogenesis of CD is crucial, since using TNFα inhibitors in these patients could favor mycobacterial infections, particularly Mycobacterium avium subspecies paratuberculosis, which ultimately could worsen their clinical condition. | Brent L Cao Ahmad Qasem Robert C Sharp Latifa S Abdelli Saleh A Naser | 2018 | World Journal of Gastroenterology2018,24,25: | 4 |
| 4 | Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions显示文摘 | Elizabeth M Brunt Christine G Janney Adrian M Di Bisceglie Brent A Neuschwander-Tetri Bruce R Bacon | 1999 | The American Journal of Gastroenterology1999,,9: | 3 |
| 5 | Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions显示文摘 | Elizabeth M Brunt Christine G Janney Adrian M Di Bisceglie Brent A Neuschwander-Tetri Bruce R Bacon | 1999 | The American Journal of Gastroenterology1999,,9: | 2 |
| 6 | A comparison of the relative efficiency of ICSI and extended culture with epididymal sperm versus testicular sperm in patients with obstructive azoospermia显示文摘This is a retrospective cohort study comparing blastocyst transfer outcomes following intracytoplasmic sperm injection utilizing epididymal versus testicular sperm for men with obstructive azoospermia.All cases at a single center between 2012 and 2016 were included.Operative approach was selected at the surgeon’s discretion and included microepididymal sperm aspiration or testicular sperm extraction.Blastocyst culture was exclusively utilized prior to transfer.The primary outcome was live birth rate.Secondary outcomes included fertilization rate,blastulation rate,euploidy rate,and implantation rate.A mixed effects model was performed.Seventy-six microepididymal sperm aspiration cases and 93 testicular sperm extraction cases were analyzed.The live birth rate was equivalent(48.6%vs 50.5%,P=0.77).However,on mixed effects model,epididymal sperm resulted in a greater likelihood of fertilization(adjusted OR:1.37,95%CI:1.05–1.81,P=0.02)and produced a higher blastulation rate(adjusted OR:1.41,95%CI:1.1–1.85,P=0.01).As a result,the epididymal sperm group had more supernumerary blastocysts available(4.3 vs 3,P<0.05).The euploidy rate was no different.Pregnancy rates were no different through the first transfer cycle.However,intracytoplasmic sperm injection following microepididymal sperm aspiration resulted in a greater number of usable blastocysts per patient.Thus,the true benefit of epididymal sperm may only be demonstrated via a comparison of cumulative pregnancy rates after multiple transfers from one cohort. | Scott J Morin Brent M Hanson Caroline R Juneau Shelby A Neal Jessica N Landis Richard T Scott Jr James M Hotaling | 2020 | Asian Journal of Andrology2020,22,2: | 2 |
| 7 | Thyroid hormone-dependent gene expression in differentiated embryonie stem cells and ernbryonal carcinoma cells : identification of novel thyroid hormone target genes by deoxyribonucleic acid microarray analysis 显示文摘 | Liu Y Y Brent G A | 2005 | Endocrinology2005,146,2: | 1 |
| 8 | Enhancement of sodium/iodide symporter expression in thyroid and breast cancer 显示文摘 | T Kogai K Taki G A Brent | 2006 | Endocrine-Related Cancer2006,13,: | 1 |
| 9 | US Trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008 显示文摘 | Brent ME Yumin Z Neal A | 2010 | JAMA2010,303,: | 1 |
| 10 | Sex-related differences in IBS patients: central processing of visceral stimuli显示文摘 | Bruce D Naliboff Steve Berman Lin Chang Stuart W.G Derbyshire Brandall Suyenobu Brent A Vogt Mark Mandelkern Emeran A Mayer | 2003 | Gastroenterology2003,,7: | 1 |
| 11 | Protein interaction methods toward an endgame显示文摘 | Mendelsohn A R Brent R | 1999 | Science1999,284,5422: | 1 |
| 12 | Symmetry-based re- sistance as a novel means of lower limb rehabilitation 显示文摘 | Simon A M Brent G R Ferris D P | 2007 | Journal of Biomechanics2007,40,6: | 1 |
| 13 | Nanolcoholic steatohepatitis显示文摘 | Brent A Bruce RB | 1996 | Med Clin North Am1996,80,: | 1 |
| 14 | Using MODIS Terra 250 m imagery to map concentrations of total suspended matter in coastal waters显示文摘 | RICHARD L M BRENT A M | 2004 | Remote Sensing of Environment2004,93,12: | 1 |
| 15 | 显示文摘 | SONYA A K MICHAEL N BRENT A K | 1997 | J Am Chem Soc1997,119,: | 1 |
| 16 | A randomized, pharmacokinetic and pharmacodynamic, cross-over study of duodenal or jejunal administration compared to nasogastric administration of omeprazole suspension in patients at risk for stress ulcers显示文摘 | Jeffrey O Phillips Keith M Olsen Jill A Rebuck Nick J Rangnekar Brent W Miedema Michael H Metzler | 2001 | The American Journal of Gastroenterology2001,,: | 1 |
| 17 | Correlation of two-hybrid affinity data with in vitro measurement显示文摘 | Estojak J Brent R Colemis E A | 1995 | Mol Cell Boil1995,,15: | 1 |
| 18 | The modeling of heat, mass and solute transport in solidification systems显示文摘 | Voller V R Brent A D Prakash C | 1989 | International Journal of Heat and Mass Transfer1989,32,9: | 1 |
| 19 | Thyroid hormone erosstalk with nuclear receptor signaling in metabolic regulation 显示文摘 | LIU Yan- yun BRENT G A | 2010 | Trends in Endocrinology and Metabolism: TEM2010,21,3: | 1 |
| 20 | Impact of land - use change and hard structures on the evolution of fringing marsh shorelines 显示文摘 | ChristopherR Antonio B Brent A | 2010 | Estuarine Coastal and Shelf Sci- ence2010,88,3: | 1 |