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| 1 | Response to endoscopic therapy for biliary anastomotic strictures in deceased versus living donor liver transplantation显示文摘BACKGROUND:Endoscopic therapy has been successful in the management of biliary complications after both deceased donor liver transplantation(DDLT) and living donor liver transplantation(LDLT).LDLT is thought to be associated with higher rates of biliary complications,but there are few studies comparing the success of endoscopic management of anastomotic strictures between the two groups.This study aims to compare our experience in the endoscopic management of anastomotic strictures in DDLT versus LDLT.METHODS:This is a retrospective database review of all liver transplant patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) after liver transplantation.The frequency of anastomotic stricture and the time to develop and to resolve anastomotic stricture were compared between DDLT and LDLT.The response of anastomotic stricture to endoscopic therapy was also analyzed.RESULTS:A total of 362 patients underwent liver transplantation between 2003 and 2011,with 125 requiring ERCP to manage biliary complications.Thirty-three(9.9%) cases of DDLT and 8(27.6%) of LDLT(P=0.01) were found to have anastomotic stricture.When comparing DDLT and LDLT,there was no difference in the mean time to the development of anastomotic strictures(98±17 vs 172±65 days,P=0.11),likelihood of response to ERCP [22(66.7%) vs 6(75.0%),P=0.69],mean time to the resolution of anastomotic strictures(268±77 vs 125±37 days,P=0.34),and the number of ERCPs required to achieve resolution(3.9±0.4 vs 4.7±0.9,P=0.38).CONCLUSIONS:Endoscopic therapy is effective in the majority of biliary complications relating to liver transplantation.Anastomotic strictures occur more frequently in LDLT compared with DDLT,with equivalent endoscopic treatment response and outcomes for both groups. | Calvin HY Chan Fergal Donnellan Michael F Byrne Alan Coss Mazhar Haque Holly Wiesenger Charles H Scudamore Urs P Steinbrecher Alan A Weiss Eric M Yoshida | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 7 |
| 2 | The laser drilling of multi-layer aerospace material systems显示文摘 | A Corcoran L Sexton B Seaman P Ryan G Byrne | 2002 | Journal of Materials Processing Tech2002，，1： | 1 |
| 3 | Frequency selectivity, multistability, and oscillations emerge from models ofgenetic regulatory systems显示文摘 | SMOLEN P BAXTER D A BYRNE J H | 1998 | Amer J Phys1998，274，： | 1 |
| 4 | Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52)显示文摘 | Byrne J A Mattie M G Basset P | 1996 | Genomics1996，35，3： | 1 |
| 5 | VODE: a variable coefficient ODE solver 显示文摘 | Brown P N Byrne G D Hindmarsh A C | 1989 | SIAM Journal on Scientific Computing1989，10，： | 1 |
| 6 | Characterization of the Mississippian chat in south-central Kansas显示文摘 | Watney W L Guy W J Byrnes A P | 2001 | AAPG Bulletin2001，85，1： | 1 |
| 7 | Detection of ban- ned nitrofuran metabolites in animal plasma samples using UHPLC-MS/MS显示文摘 | Radovnikovic A Moloney M Byrne P | 2011 | Journal of Chromatography B2011，8792，： | 1 |
| 8 | Water treatment using nano-crystalline TiO2 electrodes 显示文摘 | J A Byrne A Davidson P S M Dunlop | 2002 | Journal of Photochemistry and Photobiology A: Chemistry2002，148，： | 1 |
| 9 | Flow unit modeling and fine-scale predicted permeability validation in Alokan sandstones: Norcan East Kansas显示文摘 | Bhattacharya S Byrnes A P Watney W L | 2008 | AAPG Bulletin2008，92，6： | 1 |
| 10 | The Photocatalytic Removal of Bacterial Pollutants from Drinking Water显示文摘 | Dunlop P S M Byrne J A Manga N et 81 | 2002 | Journal of Photochemistry and Photobiology A-Chemistry2002，148，： | 1 |
| 11 | Schizotypal components in people at high risk of developing schizophrenia:early findings from the Edin- burgh High-Risk Study显示文摘 | Miller P Byrne M Hodges A | 2002 | Br J Psychiatry2002，180，： | 1 |
| 12 | Preliminary experience of allogeneic stem cell transplantation for lymphoproliferative disorders using BEAM-CAMPATH conditioning; an effective regim-en with low procedure-related toxicity显示文摘 | G M Cull A P Kaynes J L Byrne | 2002 | Br J Haematol2002，108，： | 1 |
| 13 | Frequency selectivity, multistability, and oscillations emerge from models of genetic regulatory systems 显示文摘 | Smolen P Baxter D A Byrne J H | 1998 | Am J Physiol1998，274，： | 1 |
| 14 | VODE, a variable-coefficient ODE solver显示文摘 | Brown P D Byrne G D Hindmarsh A C | 1989 | SIAM Journal on Scientific and Statistical Com- puting1989，10，5： | 1 |
| 15 | Binding of Sindbis virus to cell sur- face heparan sulfate显示文摘 | BYRNES A P GRIFFIN D E | 1998 | J Virol1998，72，： | 1 |
| 16 | Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease显示文摘AIM To investigate the independent effects of 6-mo of dietary energy restriction or exercise training on wholebody and hepatic fat oxidation of patients with nonalcoholic fatty liver disease(NAFLD).METHODS Participants were randomised into either circuit exercise training(EX;n = 13;3 h/wk without changes in dietary habits),or dietary energy restriction(ER) without changes in structured physical activity(ER;n = 8).Respiratory quotient(RQ) and whole-body fat oxidation rates(Fatox) were determined by indirect calorimetry under basal,insulin-stimulated and exercise conditions.Severity of disease and steatosis was determined by liver histology;hepatic Fatox was estimated from plasma β-hydroxybutyrate co.ncentrations;cardiorespiratory fitness was expressed as VO2 peak.Complete-case analysis was performed(EX:n = 10;ER:n = 6).RESULTS Hepatic steatosis and NAFLD activity score decreased with ER but not with EX.β-hydroxybutyrate concentrations increased significantly in response to ER(0.08 ± 0.02 mmol/L vs 0.12 ± 0.04 mmol/L,P = 0.03) but remained unchanged in response to EX(0.10 ± 0.03 mmol/L vs 0.11 ± 0.07 mmol/L,P = 0.39).Basal RQ decreased(P = 0.05) in response.to EX,while this change was not significant after ER(P = 0.38).VO_(2peak)(P < 0.001) and maximal Fa_(tox) during aerobic exercise(P = 0.03) improved with EX but not with ER(P > 0.05).The increase in β-hydroxybutyrate concentrations was correlated with the reduction in hepatic steatosis(r =-0.56,P = 0.04).CONCLUSION ER and EX lead to specific benefits on fat metabolism of patients with NAFLD.Increased hepatic Fat_(ox) in response to ER could be one mechanism through which the ER group achieved reduction in steatosis. | Ilaria Croci Nuala M Byrne Veronique S Chachay Andrew P Hills Andrew D Clouston Trisha M O'Moore-Sullivan Johannes B Prins Graeme A Macdonald Ingrid J Hickman | 2016 | World Journal of Hepatology2016，8，27： | 1 |
| 17 | Characterization of a Chi- nese hamster ovary cell line developed by retroviral insertional mu- tagenesis that is resistant to Sindbis virus infection 显示文摘 | JAN J T BYRNES A P GRIFFIN D E | 1999 | J Virol1999，73，： | 1 |
| 18 | New insights into the mechanisms of polymorphic light eruption:resistance to ultraviolet radiation-induced immune suppression as an actiological factor显示文摘 | Wolf P Byrne SN Gruber-Wackemagel A | 2009 | Exp Dennatol2009，18，4： | 1 |
| 19 | VODE, a variable-coefficient ODE solver显示文摘 | Brown P N Byrne G D Hindmarsh A C | 1989 | SIAM Journal of Scientific and Statistical Computing1989，10，5： | 1 |
| 20 | VODE: A variable coefficient ODE solver显示文摘 | Brown P N Byrne G D Hindmarsh A C | 1989 | SIAM Journal on Scientif- ic Computing1989，10，： | 1 |
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