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| 1 | Current understanding of the functional roles of aberrantly expressed micro RNAs in esophageal cancer显示文摘The incidence of esophageal cancer is rising,mostly because the increasing incidence of esophageal adenocarcino main Western countries.Despit eimprovements in diagnosis and treatment,the overall5-year survival rates remain low.Micro RNAs(mi RNAs)are small non-coding RNA molecules that regulate the expression of target genes.Recently,disease specific mi RNAs have been identified,which act as tumor suppressors or oncogenes.In this review,we will summarize the current knowledge about the function of aberrantly expressed mi RNAs in esophageal cancer.We selected 5 mi RNAs(mi RNA-21,-143,-145,-196a and let-7)based on the available literature,and described their potential role in regulating pathways that are deregulated in esophageal cancer.Finally we will highlight the current achievements of using and targeting mi RNAs.Because these mi RNAs likely have important regulatory roles in cancer development,they open a therapeutic window for new treatment modalities. | Christine Kestens Peter D Siersema Jantine WPM van Baal | 2016 | World Journal of Gastroenterology2016，22，1： | 5 |
| 2 | Effect of rumen-protected choline on performance, blood metabolites, and hepatic triacylglycerols of periparturient dairy cattle显示文摘 | R.L.G. Zom J. van Baal R.M.A. Goselink J.A. Bakker M.J. de Veth A.M. van Vuuren | 2011 | Journal of Dairy Science2011，，8： | 2 |
| 3 | Effects of feeding rapeseed oil, soybean oil, or linseed oil on stearoyl-CoA desaturase expression in the mammary gland of dairy cows显示文摘 | Jacobs A A A van Baal J Smits M A | 2011 | Journal of Dairy Science2011，94，2： | 1 |
| 4 | Preparation and mechanical properties of ultrafine grained metals显示文摘 | Gunther B Baal man A Weiss H | 1990 | Journal of materials research1990，5，： | 1 |
| 5 | Systematic review of percutaneous catheter drainage as primary treatment for necrotizing pancreatitis显示文摘 | van Baal MC van Santvoort HC Bollen TL | 2011 | Br J Surg2011，98，1： | 1 |
| 6 | Effects of lowdose oral and transdermal estrogen replacement therapy on hemostatic factors in healthy postmenopansal women: a randomized placebo-controlled study显示文摘 | Post MS van der Mooren M J van Baal WM | 2003 | Am J Obstet Gyneco12003，189，5： | 1 |
| 7 | Association between probiotics and enteral nutrition in an experimental acute pancreatitis model in rats 显示文摘 | VAN BAAL MC VAN RENS M J GEVEN CB et al | 2014 | Pancreatology2014，14，6： | 1 |
| 8 | The gonadotropins: tissue-specific angiogenic factors? 显示文摘 | Reisinger K Baal N McKinnon T | 2007 | Mol Cell Endoerinol2007，269，12： | 1 |
| 9 | Effect of rumen-protected choline supplementation on liver and adipose gene expression during the transition period in dairy cattle显示文摘 | Goselink R M van Baal J Widjaja H C | 2013 | J Dairy Sci2013，96，2： | 1 |
| 10 | SET-CAN,the product of the t(9;9) in acute undifferentiated leukemia,causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice显示文摘 | Ozbek U Kandilci A van Baal S | | 0，，02： | 1 |
| 11 | Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta显示文摘 | Herr F Schreiner I Baal N | 2011 | Placenta2011，32，8： | 1 |
| 12 | Systematic review of percutaneous catheter drainage as primary treatment for necrotizing pancreatitis显示文摘 | van Baal MC van Santvoort HC Bollen TL | 2011 | Br J Surg2011，98，1： | 1 |
| 13 | Effect of rumen-protected choline supplemen- tation on liver and adipose gene expression during the transition period in dairy cattle 显示文摘 | GOSELINK R M A VAN BAAL J WIDJAJA H C A | 2012 | Journal of Dairy Science2012，96，2： | 1 |
| 14 | The transloca-tion(6;9),associated with a specific subtype of acute myeloid leukemia,results in the fusion of two genes,dek and can,and the expression of a chimeric,leukemia-specific dek-can mRNA显示文摘 | von Lindern M Fornerod M van Baal S | | 0，，04： | 1 |
| 15 | Effect of rumen-protected choline on performance,blood metabolites, and hepatic triacylglycerols of peri- parturient dairy cattle 显示文摘 | ZOM R L G VAN BAAL J GOSELINK R M A | 2011 | Journal of Dairy Science2011，94，8： | 1 |
| 16 | Ambulatory-not office-blood pressures decline during hormone replacement therapy in healthy postmenopausal women 显示文摘 | van Lttersum F J van Baal W M Kenemans P | 1998 | Am J Hypertens1998，11，： | 1 |
| 17 | Systematic review of percutaneous catheter drainage as primary treatment for necrotizing pancreatitis 显示文摘 | van Baal MC van Santvoort HC Bollen TL | 2011 | Br J Surg2011，98，1： | 1 |
| 18 | Heritability of education- al achievement in 12-year-olds and the overlap with cognitive ability 显示文摘 | Bartels M Rietveld M J Van Baal GC | 2002 | Twin Res2002，5，6： | 1 |
| 19 | From open radical hysterectomy to robot-assisted laparoscopic radical hysterectomy for early stage cervical cancer:aspects of a single institution learning curve 显示文摘 | Schreuder HW Zweemer RP van Baal WM | 2010 | Gynecol Surg2010，7，3： | 1 |
| 20 | Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes : characterization of the set gene显示文摘 | von Lindern M van Baal S Wiegant J | 1992 | Mol Cell Biol1992，12，8： | 1 |
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