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| 1 | Evaluation of mine scale longwall top coal caving parameters using continuum analysis显示文摘A mine-scale analysis of Longwall Top Coal Caving (LTCC) is performed using a continuum mechanics finite element solver called COSFLOW. The uniqueness of COSFLOW is that it incorporates Cosserat continuum theory in its formulation for describing the load deformation of bedded rocks. It is shown that such a continuum based code is valuable for assessing the feasibility of introducing LTCC in any mine. Various LTCC parameters, for example chock convergences, top coal failure behavior, strata cavingmechanism, abutment stresses and vertical stresses, were evaluated for a mine using COSFLOW. | Manoj Khanal Deepak Adhikary Rao Balusu | 2011 | Mining Science and Technology2011，21，6： | 9 |
| 2 | Inertisation options for BG method and optimisation using CFD modelling显示文摘Spontaneous combustion(sponcom) is one of the issues of concern with the blasting gallery(BG) method of coal mining and has the potential to cause fires, and impact on production and safety, greenhouse gas(GHG) emissions and huge costs involved in controlling the aftermath situations. Some of the research attempts made to prevent and control coal mine fires and spontaneous combustion in thick seams worked with bord and pillar mining methods are presented in this paper. In the study, computational fluid dynamics(CFD) modelling techniques were used to simulate and assess the effects of various mining methods, layouts, designs, and different operational and ventilation parameters on the flow of goaf gases in BG panels. A wide range of parametric studies were conducted to develop proactive strategies to control and prevent ingress of oxygen into the goaf area preventing spontaneous combustion and mine fires. | Morla Ramakrishna Balusu Rao Tanguturi Krishna Ting Ren | 2015 | International Journal of Mining Science and Technology2015，25，3： | 3 |
| 3 | The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease:more than just a barrier显示文摘The choroid plexus is a complex structure which hangs inside the ventricles of the brain and consists mainly of choroid plexus epithelial(CPE) cells surrounding fenestrated capillaries.These CPE cells not only form an anatomical barrier,called the blood-cerebrospinal fluid barrier(BCSFB),but also present an active interface between blood and cerebrospinal fluid(CSF).CPE cells perform indispensable functions for the development,maintenance and functioning of the brain.Indeed,the primary role of the choroid plexus in the brain is to maintain homeostasis by secreting CSF which contains different molecules,such as nutrients,neurotrophins,and growth factors,as well as by clearing toxic and undesirable molecules from CSF.The choroid plexus also acts as a selective entry gate for leukocytes into the brain.Recent findings have revealed distinct changes in CPE cells that are associated with aging and Alzheimer's disease.In this review,we review some recent findings that highlight the importance of the CPE-CSF system in Alzheimer's disease and we summarize the recent advances in the regeneration of brain tissue through use of CPE cells as a new therapeutic strategy. | Sriram Balusu Marjana Brkic Claude Libert Roosmarijn E.Vandenbroucke | 2016 | Neural Regeneration Research2016，11，4： | 2 |
| 4 | Numerical analysis and geotechnical assessment of mine scale model显示文摘Various numerical methods are available to model,simulate,analyse and interpret the results;however a major task is to select a reliable and intended tool to perform a realistic assessment of any problem.For a model to be a representative of the realistic mining scenario,a verified tool must be chosen to perform an assessment of mine roof support requirement and address the geotechnical risks associated with longwall mining.The dependable tools provide a safe working environment,increased production,efficient management of resources and reduce environmental impacts of mining.Although various methods,for example,analytical,experimental and empirical are being adopted in mining,in recent days numerical tools are becoming popular due to the advancement in computer hardware and numerical methods.Empirical rules based on past experiences do provide a general guide,however due to the heterogeneous nature of mine geology(i.e.,none of the mine sites are identical),numerical simulations of mine site specific conditions would lend better insights into some underlying issues.The paper highlights the use of a continuum mechanics based tool in coal mining with a mine scale model.The continuum modelling can provide close to accurate stress fields and deformation.The paper describes the use of existing mine data to calibrate and validate the model parameters,which then are used to assess geotechnical issues related with installing a new high capacity longwall mine at the mine site.A variety of parameters,for example,chock convergences,caveability of overlying sandstones,abutment and vertical stresses have been estimated. | Khanal Manoj Adhikary Deepak Balusu Rao | 2012 | International Journal of Mining Science and Technology2012，22，5： | 2 |
| 5 | Proactive inertization to prevent beatings and fires in longwall goafs显示文摘 | R Balusu T Ren P Humphries | 2006 | Coal Inter- national2006，254，3： | 1 |
| 6 | Transforming growth factor-beta receptor signaling in cancer显示文摘 | Narayan S 331angasamy T Balusu R | 2005 | Front Biosci2005，10，6： | 1 |
| 7 | Optimization of critical medium components using response surface methodology for ethanol production from cellulosic biomass by Clostridium thennocellum SS19显示文摘 | Balusu R Paduru R R Kuravi S | 2005 | Process Biochemistry2005，40，： | 1 |
| 8 | Goaf Gas Flow Mechanics and Development of Gas and Spontaneous Combustion Control Strategies at a Highly Gassy Mine 显示文摘 | Balusu R Deguehi G Holland R | 2002 | Coal and Safety2002，20，： | 1 |
| 9 | CFD Modelling of Goal Gas Migration to Improve the Control of Spontaneous Combustion in longwalls 显示文摘 | Ren T Balusu R | 2005 | Coal 2005 Conference2005，，： | 1 |
| 10 | CFD Modeling of Longwall Goaf Gas Flow Dynamics 显示文摘 | Wendt M Balusu R | 2002 | Coal and Safety2002，20，： | 1 |
| 11 | Optimization of Critical Medium Components Using Response Surface Methodology for Ethanol Production from Cellulosic Biomass by Clostridium Thennocellum SS19显示文摘 | Balusu R Paduru R R Kuravi S K | 2005 | Process Biochemistry2005，40，9： | 1 |
| 12 | Transforming growth factor-beta receptor signaling in cancer显示文摘 | Narayan S Thangasamy T Balusu R | 2005 | Front Biosci2005，1，10： | 1 |
| 13 | Multifunctionalnanocarriers for mammographic quantification of tumordosing and prognosis of breast cancer therapy显示文摘 | Karathanasis E Chan L Balusu SR | 2008 | Biomaterials2008，29，36： | 1 |
| 14 | Optimization of critical medium components using response surface methodology for ethanol production from cellulosic biomass by Clostridium thermocellum SS19显示文摘 | Balusu Ramesh Paduru Ramamohan R Kuravi S K | 2005 | Process Biochemistry2005，40，： | 1 |
| 15 | Cigarette smoke condensate-induced level of adenomatous polyposis colib locks longpatchbase excision repair in breast epithelial cells 显示文摘 | KUNDU C N BALUSU R JAISWAL A S | 2007 | Oncogene2007，26，： | 1 |
| 16 | CFD modeling of long wallgoaf gas flow dynamics显示文摘 | WENDT M BALUSU R | 2002 | Coal and Safety2002，，20： | 1 |
| 17 | Effect of strata properties and panel widths on chock performance显示文摘The selection of optimum chock (support) capacity is very crucial for a successful longwall mining. The selection of chock capacity depends on the site-specific geotechnical parameters, constraints and longwall panel geometry, which are generally not known in detail in priority. Hence, based on the field and laboratory data, various possible combinations should be analyzed to cater for the unforeseeable mining conditions. This paper discusses the use of numerical model for selecting an appropriate chock capacity based on the site-specific geological and geotechnical information and longwall panel geometry. The fracture mechanisms of immediate and main roofs are also discussed for various panel widths and support capacities. For the models considered, the chock convergence is predicted to increase by about 33% due to the increase in face width from 100 to 260 m. Similarly, the massive roof strata are found to yield higher chock convergence compared to bedded strata. | Manoj Khanal Deepak Adhikary Rao Balusu | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，S1： | 1 |
| 18 | Transforming growth factor-beta receptor signaling in cancer显示文摘 | Narayan S Thangasamy T Balusu R | 2005 | Front Biosci2005，10，： | 1 |
| 19 | Transforming growth factor-beta receptor signaling in cancer 显示文摘 | Narayan S Thangasamy T Balusu R | 2005 | Front Biosci2005，10，5： | 1 |
| 20 | Goal gas flow mechanics and development of gas and Sponcom control strategies at a highly gassy mine显示文摘 | BALUSU R G MALLETT C | 2002 | Coal and Sa{ety2002，20，5： | 1 |
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