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| 1 | Improvement of diabetes and hypertension after gastrectomy: A nationwide cohort study显示文摘AIM: To evaluate the effect of gastrectomy on diabetes mellitus(DM) and hypertension(HTN) in non-obese gastric cancer patients. METHODS: A total of 100000 patients, diagnosed with either type 2 DM or HTN, were randomly selected from the 2004 Korean National Health Insurance System claims. Among them, 360 diabetes and 351 hypertensive patients with gastric cancer who had been regularly treated without chemotherapy from January 2005 to December 2010 were selected. They were divided into three groups according to their treatment methods: total gastrectomy(TG), subtotal gastrectomy(STG) and endoscopic resection(ER). RESULTS: The drug discontinuation rate of antidiabetic and anti-hypertensive agents after gastric cancer treatment was 9.7% and 11.1% respectively. DM appeared to be improved more frequently(22.8%) and earlier(mean ± SE 28.6 ± 1.8 mo) in TG group than in the two other groups [improved in 9.5% of ER group(37.4 ± 1.1 mo) and 6.4% of STG group(47.0 ± 0.8 mo)]. The proportion of patients treated with multiple drugs decreased more notably in TG group compared to others(P = 0.001 in DM, and P = 0.035 in HTN). In TG group, adjusted hazard ratio for theimprovement of DM was 2.87(95%CI: 1.15-7.17) in a multi-variate analysis and better control of DM was observed with survival analysis(P < 0.001).CONCLUSION: TG was found to decrease the need for anti-diabetic medications which can be reflective of improved glycemic control, to a greater extent than either ER or STG in non-obese diabetic patients. | Eun Kyung Lee So Young Kim You Jin Lee Mi Hyang Kwak Hak Jin Kim Il Ju Choi Soo-Jeong Cho Young Woo Kim Jong Yeul Lee Chan Gyoo Kim Hong Man Yoon Bang Wool Eom Sun-Young Kong Min Kyong Yoo Jong Hyock Park Keun Won Ryu | 2015 | World Journal of Gastroenterology2015，21，4： | 3 |
| 2 | Tissue engineered regeneration of completely transected spinal cord using human mesenchymal stem cells显示文摘 | Kkot Nim Kang Da Yeon Kim So Mi Yoon Ju Young Lee Bit Na Lee Jin Seon Kwon Hyo Won Seo Il Woo Lee Ha Cheol Shin Young Man Kim Hyun Soo Kim Jae Ho Kim Byoung Hyun Min Hai Bang Lee Moon Suk Kim | 2012 | Biomaterials2012，，19： | 1 |
| 3 | Zn-doped nickel iron(oxy)hydroxide nanocubes passivated by polyanions with high catalytic activity and corrosion resistance for seawater oxidation显示文摘Electrochemical water splitting to produce hydrogen fuel is a promising renewable energy-conversion technique.Large-scale electrolysis of freshwater may deplete water resources and cause water scarcity worldwide.Thus,seawater electrolysis is a potential solution to the future energy and water crisis.In seawater electrolysis,it is critical to develop cost-effective electrocatalysts to split seawater without chloride corrosion.Herein,we present zinc-doped nickel iron(oxy)hydroxide nanocubes passivated by negatively charged polyanions(NFZ-PBA-S)that exhibits outstanding catalytic activity,stability,and selectivity for seawater oxidation.Zn dopants and polyanion-rich passivated surface layers in NFZ-PBA-S could effectively repel chlorine ions and enhance corrosion resistance,enabling its excellent catalytic activity and stability for seawater oxidation. | So Jung Kim Heechae Choi Jeong Ho Ryu Kang Min Kim Sungwook Mhin Arpan Kumar Nayak Junghwan Bang Minyeong Je Ghulam Ali Kyung Yoon Chung Kyeong-Han Na Won-Youl Choi Sunghwan Yeo Jin Uk Jang HyukSu Han | 2023 | Journal of Energy Chemistry2023，，6： | 1 |
| 4 | Effects of ulinastatin on coagulation in high-risk patients undergoing off-pump coronary artery bypass graft surgery 显示文摘 | Kim NY Shim JK Bang SO | 2013 | Korean J Anesthesiol2013，64，： | 1 |
| 5 | Effects of Korean Red Ginseng ( Panax ginseng ), urushiol ( Rhus vernicifera Stokes), and probiotics ( Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052) on the gut–liver axis of alcoholic liver disease显示文摘 | Chang Seok Bang So Hyung Hong Ki Tae Suk Jin Bong Kim Sang Hak Han Hotaik Sung Eun Ji Kim Myoung Jo Kim Moon Young Kim Soon Koo Baik Dong Joon Kim | 2014 | Journal of Ginseng Research2014，，： | 1 |
| 6 | Sympathetic block for treating primary erythromelalgia 显示文摘 | Bang YJ Yeo JS Kim SO eta1 | 2010 | Korean J Pain2010，23，1： | 1 |
| 7 | Characterisation of allergen-specific responses of IL-10-producing regulatory B cells (Br1) in Cow Milk Allergy显示文摘 | Joonyong Noh Jae Ho Lee Geunwoong Noh So Young Bang Hyuk Soon Kim Wahn Soo Choi Sunheui Cho Sang Sun Lee | 2010 | Cellular Immunology2010，，： | 1 |
| 8 | Reversine Induces Multipotency of Lineage-Committed Cells through Epigenetic Silencing of miR-133a显示文摘 | Munkyung Kim Sang Ah Yi Hyunwoo Lee So Young Bang Eun Kyung Park Min Gyu Lee Ki Hong Nam Ji Hee Yoo Dong Hoon Lee Hyun-Wook Ryu So Hee Kwon Jeung-Whan Han | 2014 | Biochemical and Biophysical Research Communications2014，，： | 1 |
| 9 | Effects of ulinastatin on coagulation in high- risk patients undergoing off-pump coronary artery bypass graft surgery显示文摘 | Kim NY Shim JK Bang SO | 2013 | Korean J Anesthesiol2013，64，2： | 1 |
| 10 | Effects of uli- nastatin on coagulation in high-risk patients under- going off-pump coronary artery bypass graft sur- gery显示文摘 | Kim NY Shim JK Bang SO | 2013 | Korean Anesthesiol2013，64，2： | 1 |
| 11 | TRAF1 polymorphisms associated with rheumatoid arthritis susceptibility in Asians and in Caucasians 显示文摘 | Tae - UN Han So - Young Bang Changwon Kang | 2009 | Arthritis Rheumatism2009，60，9： | 1 |
| 12 | Comparison of the effects of nicardipine and sodium nitroprusside for control of increased blood pressure after coronary artery bypass graft surgery显示文摘 | Kwak YL Oh YJ Bang SO | 2004 | J Int Med Res2004，32，4： | 1 |
| 13 | A new catalyst for glyox- al durable press finish of cotton fabrics 显示文摘 | Young Ha Yu Eui So Lee Eun Sook Bang | 2008 | Fibers and Polymers2008，9，6： | 1 |
| 14 | Preparation of graphene with few defects using expanded graphite and rose Bengal显示文摘 | G S Bang H-M So M J Lee | 2012 | J Mater Chem2012，22，： | 1 |
| 15 | Incidence and predictors of postextubation laryngeal edema in pedistric patients with congenital heart disease显示文摘 | Koh SO Bang SO Hong YW | 1995 | Yonsei Med J1995，36，： | 1 |
| 16 | LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer显示文摘Prostate cancer(PCa)is the most commonly diagnosed genital cancer in men worldwide.Around 80%of the patients who developed advanced PCa suffered from bone metastasis,with a sharp drop in the survival rate.Despite great efforts,the detailed mechanisms underlying castration-resistant PCa(CRPC)remain unclear.Sirtuin 5(SIRT5),an NAD+-dependent desuccinylase,is hypothesized to be a key regulator of various cancers.However,compared to other SIRTs,the role of SIRT5 in cancer has not been extensively studied.Here,we revealed significantly decreased SIRT5 levels in aggressive PCa cells relative to the PCa stages.The correlation between the decrease in the SIRT5 level and the patient’s reduced survival rate was also confirmed.Using quantitative global succinylome analysis,we characterized a significant increase in the succinylation at lysine 118(K118su)of lactate dehydrogenase A(LDHA),which plays a role in increasing LDH activity.As a substrate of SIRT5,LDHA-K118su significantly increased the migration and invasion of PCa cells and LDH activity in PCa patients.This study reveals the reduction of SIRT5 protein expression and LDHA-K118su as a novel mechanism involved in PCa progression,which could serve as a new target to prevent CPRC progression for PCa treatment. | Oh Kwang Kwon In Hyuk Bang So Young Choi Ju Mi Jeon Ann-Yae Na Yan Gao Sam Seok Cho Sung Hwan Ki Youngshik Choe Jun Nyung Lee Yun-Sok Ha Eun Ju Bae Tae Gyun Kwon Byung-Hyun Park Sangkyu Lee | 2023 | Genomics, Proteomics & Bioinformatics2023，21，1： | 0 |
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