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| 1 | Comparative effect of electroacupuncture and moxibustion on the expression of substance P and vasoactive intestinal peptide in patients with irritable bowel syndrome显示文摘OBJECTIVE: To compare the impacts of electroacupuncture(EA) and moxibustion(Mox) on the primary gastrointestinal symptoms and the expressions of colonic mucosa-associated neuropeptide substance P(SP) and vasoactive intestinal peptide(VIP)in patients with either diarrhea-predominant or constipation-predominant irritable bowel syndrome(IBS-D and IBS-C,respectively).METHODS: Eighty-five IBS patients were randomly allocated to the EA and Mox groups. Zusanli(ST 36)and Shangjuxu(ST 37) were selected as acupoints for electroacupuncture or warm moxibustion treatment once a day for 14 consecutive days. Before and after the treatment sessions,a Visual Analog Pain Scale and the Bristol Stool Form Scale were used to evaluate gastrointestinal symptoms. There were four dropout cases,leaving 81 participants(41 with IBS-D and 40 with IBS-C) who volunteered to undergo colonoscopy before and after the treatment sessions. During colonoscopy,sigmoid mucosa were collected to detect SP and VIP expression using immunohistochemistry assay.RESULTS: Both EA and Mox treatments were effective at relieving abdominal pain in IBS-D and IBS-C patients. However,Mox was more effective at reducing diarrhea in IBS-D patients,whereas EA was more effective at improving constipation in IBS-C patients. EA and Mox treatments both down-regulated the abnormally increased SP and VIP expression in the colonic mucosa,with no significant difference shown between the two treatments.CONCLUSION: Both EA and Mox treatments are effective at ameliorating gastrointestinal symptoms by reducing SP and VIP expression in the colonic mucosa of IBS patients. | Lu Zhenzhong Yin Xiaojun Teng Weijun Chen Yuehua Sun Jie Zhao Jimeng Wang Anqi Bao Chunhui Shi Yin | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 24 |
| 2 | Mild moxibustion at Tianshu (ST 25) decreases expression of prokineticin-1 and prokineticin receptor-1 in colon tissue of rats with chronic visceral hyperalgesia显示文摘Prokineticin-1 and prokineticin receptor-1 play important roles in visceral hypersensitivity and in-flammatory pain. Visceral hypersensitivity is closely associated with irritable bowel syndrome. Mild moxibustion can relieve chronic visceral hyperalgesia in rats with irritable bowel syndrome. We hypothesized that prokineticin-1 and prokineticin receptor-1 is the key target in the mechanism. This study established chronic visceral hyperalgesia rat models by colorectal distention. Protein and mRNA expression of prokineticin-1 and prokineticin receptor-1 were determined by immunohisto-chemical method and fluorescence quantitative-PCR, respectively, and were found to be signifi-cantly increased in visceral hyperalgesic rats. Mild moxibustion at Tianshu (ST 25) decreased prokineticin-1 and prokineticin receptor-1 expression in chronic visceral hyperalgesia rats and lessen the chronic visceral hyperalgesia in rats with irritable bowel syndrome at different levels of colorectal distention pressure. | Luyi Wu Chunhui Bao Linbao Ge Cili Zhou Huirong Liu Li Qi Tao Yi Huangan Wu Xiaomei Wang | 2011 | Neural Regeneration Research2011，6，33： | 9 |
| 3 | Effective regeneration of high-performance anode material recycled from the whole electrodes in spent lithium-ion batteries via a simplified approach显示文摘Along with the extensive application of energy storage devices,the spent lithium-ion batteries(LIBs)are unquestionably classified into the secondary resources due to its high content of several valuable metals.However,current recycling methods have the main drawback to their tedious process,especially the purification and separation process.Herein,we propose a simplified process to recycle both cathode(LiCoO_(2))and anode(graphite)in the spent LIBs and regenerate newly high-performance anode material,CoO/CoFe2O4/expanded graphite(EG).This process not only has the advantages of succinct procedure and easy control of reaction conditions,but also effectively separates and recycles lithium from transition metals.The 98.43%of lithium is recovered from leachate when the solid product CoO/CoFe2O4/EG is synthesized as anode material for LIBs.And the product exhibits improved cyclic stability(890 mAh g^(-1) at 1 A g^(-1) after 700 cycles)and superior rate capability(208 mAh g^(-1) at 5 A g^(-1)).The merit of this delicate recycling design can be summarized as three aspects:the utilization of Fe impurity in waste LiCoO_(2),the transformation of waste graphite to EG,and the regeneration of anode material.This approach properly recycles the valuable components of spent LIBs,which introduces an insight into the future recycling. | Long Ye Chunhui Wang Liang Cao Hougui Xiao Jiafeng Zhang Bao Zhang Xing Ou | 2021 | Green Energy & Environment2021，6，5： | 3 |
| 4 | Effect of warming moxibustion Tianshu(ST 25, bilateral) and Qihai(CV 6) for the treatment of diarrhea-dominant irritable bowel syndrome: a patient-blinded pilot trial with orthogonal design显示文摘OBJECTIVE: To investigate the effects of warming moxibustion Tianshu(ST 25, bilateral) and Qihai(CV6) in patients with diarrhea-dominant irritable bowel syndrome(D-IBS) by assessing predominant factors, and determining the best factor combinations and their interactions. To identify the optimal quantity of warming moxibustion Tianshu(ST 25, bilateral) and Qihai(CV 6) to achieve optimal efficacy.METHODS: An L9(3~4) orthogonal design was applied to 233 confirmed subjects based on the three most influential factors and the three most frequently used levels. Nine programs were designed.Subjects were assigned to four subgroups according to age and gender; each subject underwent one of the nine programs randomly. We selected Tianshu(ST 25, bilateral) and Qihai(CV 6). The scores of symptoms and the IBS Quality of Life(IBS-QOL) were evaluated after the final treatment.RESULTS: After treatment, clinical symptoms of all patients were significantly improved(P = 0.001).Quality of life also improved significantly(P < 0.05).For all the participants, frequency was the dominating factor regarding symptoms(P = 0.01). Duration was the dominating factor for quality of life(P =0.0001). The best combination for improving symptoms in 30-40-year-old male and female patients was two courses of 10 min each once a day, and for41-50-year-old male and female patients it was three courses of 10 min(males) or 30 min(females)twice a day. The best combination for quality of life was three courses of 20 min once a day. No interaction was found between frequency and course, or frequency and duration.CONCLUSION: Warming moxibustion Tianshu(ST25, bilateral) and Qihai(CV 6) is a promising therapy for D-IBS. To acquire optimal efficacy, the three main factors(duration, frequency and treatment course) of the warming moxibustion should reach a specific quantity and be combined appropriately. | Yang Ling Lu Yuan Zhang Haifeng Ma Xiaopeng Bao Chunhui Wu Huangan Zhao Chen Ding Guanghong Qi Li Zhou Shuang | 2017 | Journal of Traditional Chinese Medicine2017，37，4： | 1 |
| 5 | Effects of drought and salt stress on seed germination of three legumi- nous species显示文摘 | Chunhui Wu Quanzhen Wang Bao Xie | 2011 | African Journal of Biotechnology2011，10，78： | 1 |
| 6 | PyMsOfa:A Python Package for the Standards of Fundamental Astronomy(SOFA)Service显示文摘The Standards of Fundamental Astronomy(SOFA)is a service provided by the International Astronomical Union that offers algorithms and software for astronomical calculations,which was released in two versions for FORTRAN77 and ANSI C,respectively.In this work,we implement the Python package PyMsOfa for SOFA service by three ways:(1)a Python wrapper package based on a foreign function library for Python(ctypes),(2)a Python wrapper package with the foreign function interface for Python calling C code(cffi)and(3)a Python package directly written in pure Python codes from SOFA subroutines.The package PyMsOfa has fully implemented 247 functions of the original SOFA routines released on 2023 October 11.In addition,PyMsOfa is also extensively examined,which is exactly consistent with those test examples given by the original SOFA.This Python package can be suitable to not only the astrometric detection of habitable planets from the Closeby Habitable Exoplanet Survey mission,but also for the frontier themes of black holes and dark matter related to astrometric calculations and other fields.The source codes are available via http://gffzz5cdfb4eb52484407hx5b9bxx0unxn6qf5.ffgz.tsg.suse.edu.cn/project/PyMsOfa/and http://gffzz188fe103f8f1460asx5b9bxx0unxn6qf5.ffgz.tsg.suse.edu.cn/CHES2023/PyMsOfa. | Jianghui Ji Dongjie Tan Chunhui Bao Xiumin Huang Shoucun Hu Yao Dong Su Wang | 2023 | Research in Astronomy and Astrophysics2023，23，12： | 0 |
| 7 | Van der Waals heterostructure engineering by 2D space-confinement for advanced potassium-ion storage显示文摘Molybdenum disulfide (MoS_(2)) has received enormous attentions in the electrochemical energy storage due to its unique two-dimensional layered structure and relatively high reversible capacity. However, the application of MoS_(2) in potassium-ion batteries (PIBs) is restricted by poor rate capability and cyclability, which are associated with the sluggish reaction kinetics and the huge volume expansion during K+ intercalation. Herein, we propose a two-dimensional (2D) space confined strategy to construct van der Waals heterostructure for superior PIB anode, in which the MoS_(2) nanosheets can be well dispersed on reduced graphene oxide nanosheets by leveraging the confinement effect within the graphene layers and amorphous carbon. The strong synergistic effects in 2D van der Waals heterostructure can extremely promote the electron transportation and ions diffusion during K+ insertion/extraction. More significantly, the 2D space-confinement effect and van der Waals force inhibit polysulfide conversion product dissolution into the electrolyte, which significantly strengthens the structural durability during the long-term cycling process. As anticipated, the as-synthesized the “face-to-face” C/MoS_(2)/G anode delivers remarkable K-storage performance, especially for high reversible capacity (362.5 mAh·g^(-1) at 0.1 A·g^(-1)), excellent rate capability (195.4 mAh·g^(-1) at 10 Ag^(-1)) and superior ultrahigh-rate long-cycling stability (126.4 mAh·g^(-1) after 4000 cycles at high rate of 5 A·g^(-1)). This work presents a promise strategy of structure designing and composition optimization for 2D layered materials in advanced energy storage application. | Bi Luo Peng Wu Jiafeng Zhang Liang Cao Chunhui Wang Bin Lu Bao Zhang Xing Ou | 2021 | Nano Research2021，14，11： | 0 |
| 8 | Acupuncture for Crohn’s disease:current status and future perspectives显示文摘Crohn’s disease(CD),a type of inflammatory bowel disease,is a chronic,recurrent inflammatory disease of the intestine,with the main clinical manifestations including abdominal pain,diarrhea,and loss of body mass.The disease is common in Europe and the United States,and its incidence has increased in recent years in newly industrialized countries in Asia,Africa,and South America[1]. | Chunhui Bao Jinrong Zhang Huangan Wu | 2023 | Acupuncture and Herbal Medicine2023，3，4： | 0 |
| 9 | A systematic survey of LU domain-containing proteins reveals a novel human gene,LY6A,which encodes the candidate ortholog of mouse Ly-6A/Sca-1 and is aberrantly expressed in pituitary tumors显示文摘The Ly-6 and uPAR(LU)domain-containing proteins represent a large family of cell-surface markers.In particular,mouse Ly-6A/Sca-1 is a widely used marker for various stem cells;however,its human ortholog is missing.In this study,based on a systematic survey and comparative genomic study of mouse and human LU domain-containing proteins,we identified a previously unannotated human gene encoding the candidate ortholog of mouse Ly-6A/Sca-1.This gene,hereby named LY6A,reversely overlaps with a lncRNA gene in the majority of exonic sequences.We found that LY6A is aberrantly expressed in pituitary tumors,but not in normal pituitary tissues,and may contribute to tumorigenesis.Similar to mouse Ly-6A/Sca-1,human LY6A is also upregulated by interferon,suggesting a conserved transcriptional regulatory mechanism between humans and mice.We cloned the full-length LY6A cDNA,whose encoded protein sequence,domain architecture,and exon‒intron structures are all well conserved with mouse Ly-6A/Sca-1.Ectopic expression of the LY6A protein in cells demonstrates that it acts the same as mouse Ly-6A/Sca-1 in their processing and glycosylphosphatidylinositol anchoring to the cell membrane.Collectively,these studies unveil a novel human gene encoding a candidate biomarker and provide an interesting model gene for studying gene regulatory and evolutionary mechanisms. | Dan Liu Chunhui Xu Yanting Liu Wen Ouyang Shaojian Lin Aining Xu Yuanliang Zhang Yinyin Xie Qiuhua Huang Weili Zhao Zhu Chen Lan Wang Saijuan Chen Jinyan Huang Zhe Bao Wu Xiaojian Sun | 2023 | Frontiers of Medicine2023，17，3： | 0 |
| 10 | Occurrence Regularity and Mating Rhythm of Overwintering Adults of Tessaratoma papillosa on Longan Tree显示文摘[Objective] The occurrence regularity and mating rhythm of overwintering adults of Tessaratoma papillosa on longan tree were studied in the paper, so as to provide scientific reference for effective prevention and control against the pest. [Method] During the mating period of overwintering adults of T. papillosa, mating duration, occurrence regularity and mating rhythm of overwintering adults within 48 h as well as their occurrence and mating status during April and June were observed. [Result] Mating duration of T. papillosa adults for 8-9 h accounted for 18.2%, and duration for 10-11 h and more than 13 h accounted for 54.5% and 27.3%, respectively. According to daily observation, the maximum adult quantity of T. papillosa adults appeared at 9:00 am, followed by 13:00 pm. There were two peaks (9:00 am and 13:00 pm) and troughs (6:00 am and 19:00 pm) for adult quantity of T. papillosa and its mating pairs within 24 h a times changed. Mating pairs were positively correlated with observed adult quantity. Adult quantity and mating pairs increased since April 1, and reached the maximum value on April 6. Afterwards, they were gradually dropped down, and almost no adults of T. papillosa were found after June 11. [Conclusion] The mating peak of T. papillosa adults was from April to May, and there were two mating peaks (9:00 am and 13:00 pm) and troughs (6:00 am and 19:00 pm) every day. Adults repeatedly mated and spawned, while mating usually lasted for 10-11 h either during the daytime or at night. | Liu Jimin Huang Qichun Wei Ge Chen Zhenglin Huang Chaofu Wan Chunhui Jia Bao He Ningzu Lu Wen | 2013 | Plant Diseases and Pests2013，4，1： | 0 |
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