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24篇 您的检索式：作者名="Baraldini"

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	题名	作者	年代	出处	被引量
1	A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon显示文摘AIM: To develop a new formulation with hydroxy propyl methyl cellulose and Shellac coating for extended and selective delivery of butyrate in the ileo-caecal region and colon. METHODS: One-gram sodium butyrate coated tablets containing 13C-butyrate were orally administered to 12 healthy subjects and 12 Crohn's disease patients and the rate of 13C-butyrate absorption was evaluated by 13CO2 breath test analysis for eight hours. Tauroursodeoxycholic acid (500 mg) was co-administered as a biomarker of oro-ileal transit time to determine also the site of release and absorption of butyrate by the time of its serum maximum concentration. RESULTS: The coated formulation delayed the 13C-butyrate release by 2-3 h with respect to the uncoated tablets. Sodium butyrate was delivered in the intestine of all subjects and a more variable transit time was found in Crohn's disease patients than in healthy subjects. The variability of the peak 13CO2 in the kinetic release of butyrate was explained by the inter-subject variability in transit time. However, the coating chosen ensured an efficient release of the active compound even in patients with a short transit time. CONCLUSION: Simultaneous evaluation of breath 13CO2 and tauroursodeoxycholic acid concentration- time curves has shown that the new oral formulation consistently releases sodium butyrate in the ileo-cecal region and colon both in healthy subjects and Crohn's disease patients with variable intestinal transit time. This formulation may be of therapeutic value in inflammatory bowel disease patients due to the appropriate release of the active compound.	Aldo Roda Patrizia Simoni Maria Magliulo Paolo Nanni Mario Baraldini Giulia Roda Enrico Roda	2007	World Journal of Gastroenterology2007，13，7：	8
2	Early surgical management of Klippel-Trenaunay syndrome in childhood can prevent long-term haemodynamic effects of distal venous hypertension显示文摘	Baraldini V Coletti M Cipolat L	2002	J Pediatr Surg2002，37，2：	1
3	Separation techniques for bile salts analysis显示文摘	RODA A PIAZZA F BARALDINI M	1998	J Chromatogr B1998，717，12：	1
4	Separation techniques for bile salts analysis 显示文摘	Roda A Piazza F Baraldini M	1998	J Chromatogr B Biomed Sci Appl1998，717，12：	1
5	Separation techniques for bile salts analysis 显示文摘	Aldo Roda Francesco Piazza Mario Baraldini	1998	Journal of Chromatog-raphy B1998，717，：	1
6	Protein mierodeposition using a conventional ink-jet printer显示文摘	Roda A Guardigli M Russo C Pasini P Baraldini M	2000	BioTechniques2000，28，：	1
7	Taurohyodeoxycholic acid protects against taurocheno-deoxycholic acid-induced cholestasis in the rat显示文摘	Roda A Piazza F Baraldini M	1998	Hepatology1998，27，2：	1
8	Separation techniques for bilesalts analysis显示文摘	Roda A Piazza F Baraldini M	1998	J Chromatogr B1998，717，12：	1
9	Early surgical management of Klippel-Trenaunay syndrome in childhood can prevent long-term hae-modynamic effects of distal venous hypertension显示文摘	Baraldini V Coletti M Cipolat L	2002	J Pediatr Surg2002，37，2：	1
10	Noble metal containing Al/Ce/Mg pillared montmorillonite clay as catalysts in the hydrotreating of LCO fraction显示文摘	Albertazzi S Baraldini I Busca G	2005	Appl Clay Sci2005，29，34：	1
11	ISVI-IUA consensus document diagnostic guidelines of vascular anomalies:vascular malformations and hemangiomas显示文摘	Lee BB Antignani PL Baraldini V	2015	Int Angiol2015，34，4：	1
12	Separation techniques for bile salts analysis显示文摘	Roda A Piazza F Baraldini M	1998	J Chromatogr B Biomed Appl1998，717，12：	1
13	Separation techniques for bile salts analysis显示文摘	Roda A Piazza F Baraldini M		0，，：	1
14	Early surgical managementof Klippel-Trenaunay syndrome in childhood can prevent long- term haemodynamic effects of distal venous hypertension 显示文摘	Baraldini V Coletti M Cipolat L	2002	J Pediatr Surg2002，37，2：	1
15	Early surgical management of Klippel-Trenaunay syndrome in childhood can prevent long-term haemodynamic effects of distal venous hypertension显示文摘	Baraldini V Coletti M Cipolat L	2002	Pediatr Surg2002，37，2：	1
16	Bio- and chemiluminescence in bioanalysis显示文摘	A. Roda P. Pasini M. Guardigli M. Baraldini M. Musiani M. Mirasoli	2000	Fresenius’ Journal of Analytical Chemistry (-)2000，，6：	1
17	Early surgical management of Klippel-Trenaunay syndrome in childhood can prevent long-term haemodynamic effects of distal venous hypertension 显示文摘	Baraldini V Coletti M Cipolat L	2002	J Pediatr Surg2002，37，2：	1
18	Chemiluminescent imaging of enzyme-labelled probes using an optical mieroscope-vid-eocamera luminograph 显示文摘	RODA A PASINI P BARALDINI M	1998	Anal Biochem1998，257，：	1
19	Protein microdeposition using a conventional ink-jet printer显示文摘	Roda A Guardigli M Russo C Pasini P Baraldini M		0，，03：	1
20	Assessment of portal hypertension by endoscopic uhrasonography 显示文摘	Caletti G Brocchi E Baraldini M	1990	Gas- trointest Endosc1990，36，2：	1

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