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| 1 | Oxidative stress and nitric oxide in rats with alcohol-induced acute pancreatitis显示文摘AIM: Oxygen free radical mediated tissue damage is well established in pathogenesis of acute pancreatitis (AP).Whether nitric oxide (NO) plays a deleterious or a protective role is unknown. In alcohol-induced AP, we studied NO, lipooxidative damage and glutathione in pancreas, lung and circulation.METHODS: AP was induced in rats (n = 25) by injection of ethyl alcohol into the common biliary duct. A sham laparatomy was performed in controls (n = 15). After 24 h the animals were killed, blood and tissue sampling were done.RESULTS: Histopathologic evidence confirmed the development of AP. Marked changes were observed in the pulmonary tissue. Compared with controls, the AP group displayed higher values for NO metabolites in pancreas and lungs, and thiobarbituric acid reactive substances in circulation. Glutathione was lower in pancreas and in circulation. Glutathione and NO were positively correlated in pancreas and lungs of controls but negatively correlated in circulation of experimental group. In the experimental group, plasma thiobarbituric acid reactive substances were negatively correlated with pancreas thiobarbituric acid reactive substances but positively correlated with pancreas NO.CONCLUSION: NO increases in both pancreas and lungs in AP and NO contributes to the pathogenesis of AP under oxidative stress. | Gülnur Andican Remisa Gelisgen Ethem Unal Osman Baran Tortum Sergülen Dervisoglu Tayfun Karahasanoglu Gülden Bur(?)ak | 2005 | World Journal of Gastroenterology2005，11，15： | 18 |
| 2 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 3 | Risk factor for nosocomial imipenem-resistant Acinetobacter baumannii infections显示文摘 | BARAN G ERBAG A BODUR H | 2008 | Int J Infect Dis2008，12，1： | 1 |
| 4 | Numerical study of polymer surface wear caused by sliding contact显示文摘 | Sadeghipour K Baran G | 1999 | Wear1999，，224： | 1 |
| 5 | Fractal characteristics of fracture surfaces显示文摘 | BARAN G R ROQUES-CARMES C WEHBI D | 1992 | J Am Ceram Soc1992，75，10： | 1 |
| 6 | Reproducibility of uncorrected velocity of sound does not indicate true precision显示文摘 | Brandenburger G Waud K Baran D | 1992 | Bone Miner Res1992，7，1： | 1 |
| 7 | Auger chemical analysis of oxides on Ni-Cr alloys显示文摘 | Baran G | 1984 | J Dent Res1984，63，1： | 1 |
| 8 | Pneumonia due to ETt terobacter cancerogenus infection显示文摘 | Demir T Baran G Buyukguclu T | 2014 | Folia Microbiologica2014，59，6： | 1 |
| 9 | Kainic acid induced seizures:neurochemical and histopathological changes显示文摘 | SPERK G LASSSMANN H BARAN H | 1983 | Neuroscience1983，10，： | 1 |
| 10 | Risk factors for nosocomial imipenem- resistant Acinetobacter baumannii infections显示文摘 | BARAN G ERBAY A BODUR H | 2008 | J Infect Dis2008，12，： | 1 |
| 11 | Fractal analysis of woen surfaces显示文摘 | Tricot C Ferland P Baran G | 1994 | Wear1994，172，： | 1 |
| 12 | Anion encapsulation by neutral supramolecular assemblies of cyclic Cu(Ⅱ) complexes:a series of five polymerization isomers, ,n= 8,9,12,and 14显示文摘 | Mezei G Baran P Raptis R G | 2004 | Angew Chem Int Ed2004，43，： | 1 |
| 13 | Spheroidization of cementite in steel显示文摘 | BARAN OVA V A SUKHOMLIN G D | 1981 | Metal Science and Heat Treatment1981，11，： | 1 |
| 14 | IR spectra of VO2 and V2 03 显示文摘 | iBotto I L Vassallo M B Baran E J Minelli G | 1997 | Materials Science Communication1997，50，3： | 1 |
| 15 | Incidence of hypocupraemia in cattle in northern Uruguay and its alleviation with an injected Cu-Phenylalanine complex显示文摘 | Torre M H Viera I Facchin G Kremer E Baran E J Porochin T DiDonato V Irigoyen C Irigoyen J Saldanha S Bussi J Ohanian M Fuentes J | 2005 | Livestock Production Science2005，95，12： | 1 |
| 16 | Risk factor for nosocomial imipenem- resistant Acinetobacter baumannii infections显示文摘 | Baran G Erbay A Bodur H | 2008 | Int J Infect Dis2008，12，1： | 1 |
| 17 | Optical feedback cavity-enhanced absorption spectroscopy (OF-CEAS) in a ring cavity显示文摘 | Hamilton D H Nix M G D Baran S G | 2010 | Applled Physics B2010，100，： | 1 |
| 18 | Finite element analysis of the effect of an interphase on toughening of a particle-reinforced polymer composite显示文摘 | WANG Wen-hai SADEGHIPOUR K BARAN G | 2008 | Applied Science Manufacturing2008，39，6： | 1 |
| 19 | Fractal analysis of worn surfaces显示文摘 | Tricot C Ferland P Baran G | 1994 | Wear1994，，172： | 1 |
| 20 | Risk factors for nosocomi- al imipenem-resistant acinetobacter baumannii infections显示文摘 | Baran G Erbay A Bodur H | 2008 | J Infect Dis2008，12，1： | 1 |
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