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| 1 | 考虑pH值和挥发性脂肪酸影响的填埋城市固废厌氧降解模型显示文摘建立了描述填埋城市固体废弃物降解过程和行为的2阶段厌氧降解机理模型.模型考虑了含水率、挥发性脂肪酸(VFA)和p H值等主要环境因素的作用.为了适用于不同渗滤液酸化水平下的降解,单独考虑了p H值和分子态VFA对甲烷菌繁殖的影响.建立了气相高CO2分压下的渗滤液p H值计算方程,并给出了降解环境中CO2分压的计算方法.通过对一固废降解试验的模拟验证了模型的有效性.最后,采用所建立的p H值计算方程揭示了填埋环境下高CO2分压对渗滤液p H值影响显著,渗滤液p H值与VFA间缺乏不同酸化水平下的一致对应关系和高酸化水平下p H值对VFA浓度变化不敏感、分子态VFA抑制作用明显等规律. | 郭汝阳 陈云敏 李育超 詹良通 Beaven R P | 2015 | 中国环境科学2015，35，1： | 9 |
| 2 | Machine learning models compared to existing criteria for noninvasive prediction of endoscopic retrograde cholangiopancreatography-confirmed choledocholithiasis显示文摘Background and aims:Noninvasive predictors of choledocholithiasis have generally exhibited marginal performance characteristics.We aimed to identify noninvasive independent predictors of endoscopic retrograde cholangiopancreatography(ERCP)-confirmed choledocholithiasis and accordingly developed predictive machine learning models(MLMs).Methods:Clinical data of consecutive patients undergoing first-ever ERCP for suspected chol-edocholithiasis from 2015 to 2019 were abstracted from a prospectively-maintained database.Multiple logistic regression was used to identify predictors of ERCP-confirmed choledocholithiasis.MLMs were then trained to predict ERCP-confirmed choledocholithiasis using pre-ERCP ultrasound(US)imaging only as well as using all available noninvasive imaging(US,computed tomography,and/or magnetic reso-nance cholangiopancreatography).The diagnostic performance of American Society for Gastrointestinal Endoscopy(ASGE)“high-likelihood”criteria was compared to MLMs.Results:We identified 270 patients(mean age 46 years,62.2%female,73.7%Hispanic/Latino,59%with noninvasive imaging positive for choledocholithiasis)with native papilla who underwent ERCP for suspected choledocholithiasis,of whom 230(85.2%)were found to have ERCP-confirmed chol-edocholithiasis.Logistic regression identified choledocholithiasis on noninvasive imaging(odds ratio(OR)¼3.045,P¼0.004)and common bile duct(CBD)diameter on noninvasive imaging(OR¼1.157,P¼0.011)as predictors of ERCP-confirmed choledocholithiasis.Among the various MLMs trained,the random forest-based MLM performed best;sensitivity was 61.4%and 77.3%and specificity was 100%and 75.0%,using US-only and using all available imaging,respectively.ASGE high-likelihood criteria demonstrated sensitivity of 90.9%and specificity of 25.0%;using cut-points achieving this specificity,MLMs achieved sensitivity up to 97.7%.Conclusions:MLMs using age,sex,race/ethnicity,presence of diabetes,fever,body mass index(BMI),total bilirubin,maximum CBD diameter,and choledocholithiasis on pre-ERCP noninvasive imaging predict ERCP-confirmed choledocholithiasis with good sensitivity and specificity and outperform the ASGE criteria for patients with suspected choledocholithiasis. | Camellia Dalai John M Azizian Harry Trieu Anand Rajan Formosa C Chen Tien Dong Simon W Beaven James H.Tabibian | 2021 | Liver Research2021，5，4： | 3 |
| 3 | Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases显示文摘 | Sung-Jun Park Faiyaz Ahmad Andrew Philp Keith Baar Tishan Williams Haibin Luo Hengming Ke Holger Rehmann Ronald Taussig Alexandra L. Brown Myung K. Kim Michael A. Beaven Alex B. Burgin Vincent Manganiello Jay H. Chung | 2012 | Cell2012，，3： | 2 |
| 4 | Wrought magnesium alloys for structural applications 显示文摘 | LETZ1G D SWlOSTEK J BOHLEN J BEAVEN P A KAINER K U | 2008 | Material Science and Technology2008，24，8： | 1 |
| 5 | Leachate recirculation in a landfill: Some insights obtained from the development of a simple 1-D model显示文摘 | WHITE J K BEAVEN R P POWRIE W | 2011 | Waste Management2011，31，6： | 1 |
| 6 | Antibacterial activi-ties of oyster ( Crassostrea virginica) and mussel(Mytilus edulis and Geukensia demissa) plasma显示文摘 | ANDERSON R S BEAVEN A E | 2001 | Aquatic Living Resources2001，14，6： | 1 |
| 7 | Anomaly detection from hyperspectral imagery 显示文摘 | Stein D W J Beaven S G Hoff L E | 2002 | IEEE Signal Processing Magazine2002，19，1： | 1 |
| 8 | Modeling the compression behavior of landfilled domestic waste显示文摘 | HUDSON A P WHITE J K BEAVEN R P | 2004 | Waste Management2004，24，3： | 1 |
| 9 | Biomarkers in inflammatory bowel disease显示文摘 | Simon W Beaven | 2004 | Current Opinion in Gastroenterology2004，20，4： | 1 |
| 10 | Anomaly detection from hyperspectral imagery 显示文摘 | STEIN D W J BEAVEN S G HOFF L E | 2002 | IEEE Signal Processing Magazine2002，，19： | 1 |
| 11 | Anomaly detection from hyperspectral imagery显示文摘 | Stein D W J Beaven S G Hoff L E | 2002 | IEEE Transactions on Signal Processing Magazine2002，19，： | 1 |
| 12 | Anomaly detection from hyperspectral imagery 显示文摘 | STEIN D W J BEAVEN S J HOFF L E | 2002 | IEEE Signal Processing Magazine2002，19，1： | 1 |
| 13 | Anoma- ly Detection from Hyperspectral Imagery显示文摘 | Stein D W J Beaven S G Hoff L E | 2002 | IEEE Signal Processing Magazine2002，19，1： | 1 |
| 14 | A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse显示文摘 | ADVANI A S SHADMAN M ALI-OSMAN F BARKER A RYBICKI L KALAYCIO M SEKERES M A de CASTRO C M DIEHL L F MOORE J O BEAVEN A COPELAN E SOBECKS R TALEA P RIZZIERI D A | 2010 | Clinical lymphoma Myeloma & Leukemia2010，10，6： | 1 |
| 15 | A truncated splice-variant of the FcepsilonRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells显示文摘 | Cruse G Beaven MA Ashmole I | 2013 | Immunity2013，38，5： | 1 |
| 16 | Compound 48/80 activates mast cell phospolopase d viaHeterotrimeric GTP-Binding Proteins 显示文摘 | Ahmed Chahdi Paul F Fraundorfer Michael A Beaven | 2000 | J PharmacolExp Ther2000，，： | 1 |
| 17 | Syndrome X:10 years after显示文摘 | | 1999 | Drugs1999，58，1920： | 1 |
| 18 | Phosphorylation of the liverX receptors显示文摘 | Chen M Bradley MN Beaven SW | 2006 | FEBSLett2006，580，20： | 1 |
| 19 | Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha显示文摘 | Chen M Beaven S Tontonoz P | 2005 | Lipid Res2005，46，12： | 1 |
| 20 | A random blood sugar diabetes detection survey显示文摘 | Abernethy MH Andre C Beaven DW | 1977 | N Z Med J1977，86，593： | 1 |
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