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| 1 | Speckle tracking echocardiography to assess regional ventricular function in patients with apical hypertrophic cardiomyopathy显示文摘AIM To explore regional systolic strain of midwall and endocardial segments using speckle tracking echocardiography in patients with apical hypertrophic cardiomyopathy(HCM).METHODS We prospectively assessed 20 patients(mean age 53 ± 16 years,range:18-81 years,10 were male),with apical HCM. We measured global longitudinal peak systolic strain(GLPSS) in the midwall and endocardium of the left ventricle. RESULTS The diastolic thickness of the 4 apical segments was 16.25 ± 2.75 mm. All patients had a normal global systolicfunction with a fractional shortening of 50% ± 8%. In spite of supernormal left ventricular(LV) systolic function,midwall GLPSS was decreased in all patients,more in the apical(-7.3% ±-8.8%) than in basal segments(-15.5% ±-6.93%),while endocardial GLPPS was significantly greater and reached normal values(apical:-22.8% ±-7.8%,basal:-17.9% ±-7.5%). CONCLUSION This study shows that two-dimensional strain was decreased mainly confined to the mesocardium,while endocardium myocardial deformation was preserved in HCM and allowed to identify subclinical LV dysfunction. This transmural heterogeneity in systolic strain had not been previously described in HCM and could be explained by the distribution of myofibrillar disarray in deep myocardial areas. The clinical application of this novel finding may help further understanding of the pathophysiology of HCM. | María Cristina Saccheri Tomás Francisco Cianciulli Luis Alberto Morita Ricardo JoséMéndez Martín Alejandro Beck Juan Enrique Guerra Alberto Cozzarin Luciana Jimena Puente Lorena Romina Balletti Jorge Alberto Lax | 2017 | World Journal of Cardiology2017，9，4： | 7 |
| 2 | Excimer laserassisted recanalisation of feoral arterial stenosis or occusion caused by the use of Angio - Seal显示文摘 | Steinkamp HJ Werk M Beck A | 2001 | Eur Radio2001，11，： | 1 |
| 3 | Multilineage paential of adult human mesenchymal stem cells 显示文摘 | PITFENGER M F MACKAY A M BECK S C | 1999 | Science1999，284，5411： | 1 |
| 4 | Multilineage potential of adult human mesenchymal stem cells显示文摘 | Pittenger M F Mackay A M Beck S C | | 0，，5411： | 1 |
| 5 | UP-PCR analysis and ITS1 ribotyping of Trichoderma and Gliocladium fungi显示文摘 | Bulat S A Lübeck M Mironenko N V | 1998 | Mycol Res1998，102，： | 1 |
| 6 | Multilineage potential of adult human mesenchymal stem cells显示文摘 | Pittenger M F Mackay A M Beck S C | 1999 | Science1999，284，： | 1 |
| 7 | High frequency and high resolution capacitance measuring circuit for process tomography显示文摘 | Yang W Q Stott A L Beck M S | 1994 | IEE Proc Circuits Devices Syst1994，141，3： | 1 |
| 8 | Developmental neu- rotoxicity study of dietary bisphenol A in Sprague-Dawley rats显示文摘 | Stump D G Beck M J Radovsky A | 2010 | Toxicol Sci2010，115，1： | 1 |
| 9 | A fast iterative shrinkage-thresholding algorithm for linear inverse problems显示文摘 | Beck A Teboulle M | 2009 | SIAM Journal on Imaging Sciences2009，2，1： | 1 |
| 10 | IntCal09 and Marine09 radiocarbon age calibration cmwes, 0-50,000 years cal BP显示文摘 | REIMER P J BAILLIE M G L BARD E BAYLISS A BECK J W BLACKWELL P G | 2009 | Radiocarbon2009，51，4： | 1 |
| 11 | Numericalsolution of the general two-dimensional inverse heatconduction problem(IHCP)显示文摘 | OSMAN A M DOWDING K J BECK J V | 1997 | Journal of HeatTransfer1997，119，： | 1 |
| 12 | Determinants of persist- ence in canine distemper voruses显示文摘 | Stettler M Beck K Wagner A | 1997 | Vet Microbiol1997，57，1： | 1 |
| 13 | Particle Velocity and Mass Measurement in Pneumatic Conveyors 显示文摘 | Beck M S Drane J Plaskowski A Wainwright N | 1968 | Powder Technology1968，2，： | 1 |
| 14 | Managing Data Storage in the Network显示文摘 | Plank J S Bassi A Beck M T | 2001 | IEEE Internet Computing2001，5，5： | 1 |
| 15 | Relative importance of hypertension compared with hypervolemia for increasing cerebral oxygenation in patients with cerebral vasospasmafter subarachnoid hemorrhage显示文摘 | Raabe A Beck J Keller M | | 0，，06： | 1 |
| 16 | Mirror descent and nonlinear projected subgradient methods for convex optimization显示文摘 | Beck A Teboulle M | 2003 | Operations Research Letters2003，31，3： | 1 |
| 17 | Relative importance of hypertension compared with hypervolemia for increasing cerebral oxygenation in patients with cerebral vasospasm after subarachnoid hemorrhage显示文摘 | Raabe A Beck J Keller M | 2005 | J Neurosurg2005，103，6： | 1 |
| 18 | A review of electromagnetic tomography at UMIST显示文摘 | Yu Z Z Lyon G M AI -Zeibak S Peyton A J and Beck M S | 1995 | IEE Colloquium Digest1995，099，2： | 1 |
| 19 | Glutathione peroxidase protects mice from viral-induced myocarditis 显示文摘 | Beck M A Esworthy R S Ho Y S | 1998 | FASEB J1998，12，： | 1 |
| 20 | Multilineage potential of adult human mesenchymal stem cells 显示文摘 | PITTENGER M F MACKAY A M BECK SC | 1999 | Science1999，284，1： | 1 |
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