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| 1 | Alveolar echinococcosis-spreading disease challenging clinicians: A case report and literature review显示文摘Human alveolar echinococcosis (AE) is a potentially deadly disease; recent studies have shown that the endemic area of Echinococcus multilocularis , its causative agent, is larger than previously known. This disease has low prevalence and remains underreported in Europe. Emerging clinical data show that diagnostic difficulties are still common. We report on a 76-year old patient suffering from AE lesions restricted to the left lobe of the liver who underwent a curative extended left hemihepatectomy. Prior to the resection a liver biopsy under the suspicion of an atypical malignancy was performed. After the intervention he developed a pseudoaneurysm of the hepatic artery that was successfully coiled. Surprisingly, during surgery, the macroscopic appearance of the tumour revealed a growth pattern that was rather typical for cystic echinococcosis (CE), i.e. , a gross tumour composed of multiple large vesicles with several centimeters in diameter. In addition, there were neither extensive adhesions nor infiltrations of the neighboring pancreas and diaphragm as was expected from previous imaging results. The unexpected diagnosis of AE was confirmed by definite histopathology, specific polymerase chain reaction and serology results. This is a rare case of unusual macroscopic presentation of AE that posed immense diagnostic challenges and had an eventful course. To our knowledge this is the first case of an autochthonous infection in this particular geographic area of Germany, the federal state of Saxony. This report may provide new hints for an expanding area of risk for AE and emphasizes the risk of complications in the scope of diagnostic procedures and the limitations of modern radiological imaging. | Georgi Atanasov Christoph Benckert Armin Thelen Dennis Tappe Matthias Frosch Dieter Teichmann Thomas FE Barth Christian Wittekind Stefan Schubert Sven Jonas | 2013 | World Journal of Gastroenterology2013，19，26： | 14 |
| 2 | Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature显示文摘Xanthogranulomatous 胆汁(XGC ) 是胆囊的破坏煽动性的疾病,很少包含邻近的机关并且模仿国王先进胆囊癌。诊断在病理学的检查以后仅仅通常是可能的。46 42 岁的女人被指我们包含肝核,正确的肝脑叶,恰好结肠的弯曲,和十二指肠的怀疑的胆囊癌症的中心。刷细胞学获得了由内视镜后退胆管造影术(ERC ) 出现了高级发育异常。病人经历了团的在团体切除术,由正确叶切除术,正确的半结肠切除术,和部分十二指肠的切除术组成。出人意料地揭示的病理学的检查一 XGC.Only,为有邻近的机关的直接参与的 XGC 的扩大外科的切除术的六个案例到目前为止被报导了。在这些情况中,与癌给 XGC 的可能的共存,恶意不能被排除,甚至在细胞学和 intraoperative 冰冻切片调查以后。在结论,由于源于在另外的方面上包围机关的高度好攻击的煽动性的侵略的一个方面和可能的复杂并发症上的胆囊癌的差的预后,它似乎这些案例应该被当作恶性瘤直到不那样证明。临床医生们应该包括 XGC 在之中可能微分在肝核群众诊断。 | Antonino Spinelli Guido Schumacher Andreas Pascher Enrique Lopez-Hanninen Hussain Al-Abadi Christoph Benckert Igor M Sauer Johann Pratschke Ulf P Neumann Sven Jonas Jan M Langrehr Peter Neuhaus | 2006 | World Journal of Gastroenterology2006，12，14： | 13 |
| 3 | Megacolon in adulthood after surgical treatment of Hirschsprung's disease in early childhood显示文摘Hirschsprung's disease (HD) is a disorder associated with congenital malformation of the enteric nervous system with segmental aganglionosis. Prevailing therapy includes a resection of the affected part of the bowel. However, patients often do not obtain complete functional improvement after surgical treatment. We present the case of a 25-year-old woman who had surgical treatment of HD in early childhood. After that procedure she had clinical features of constipation for years in the end,passing of stool once a week, requiring laxatives and enemas. We diagnosed an incomplete resection of the aganglionic bowel via rectal biopsy and resected the remaining aganglionic segment. Two months after surgery the patient's bowel function improved to a frequency of 1-4 stools per day. We conclude that regular follow-up is required to identify HD patients with persistent alterations of bowel function after surgery. In patients presenting with constipation, recognition of a remaining aganglionic segment or other alterations of the enteric nervous system should be aimed at in an early stage. | Christoph R.Werner Gisela Stoltenburg-Didinger Henning Weidemann Christoph Benckert Marco Schmidtmann Ivo R.van der Voort Viola Andresen Burghard F.Klapp Peter Neuhaus Bertram Wiedenmann Hubert Mnnikes | 2005 | World Journal of Gastroenterology2005，11，36： | 3 |
| 4 | Surgical management of proximal bile duct cancer: extended right lobe resection increases resectability and radicality显示文摘 | Peter Neuhaus Sven Jonas Utz Settmacher Armin Thelen Christoph Benckert Enrique Lopez-H?nninen Rainer E. Hintze | 2003 | Langenbeck’s Archives of Surgery2003，，3： | 2 |
| 5 | Liver resection for hepatocellular carcinoma in patients without cirrhosis显示文摘 | A. Thelen C. Benckert H.‐M. Tautenhahn H.‐M. Hau M. Bartels J. Linnemann J. Bertolini M. Moche C. Wittekind S. Jonas | 2012 | Br J Surg2012，，1： | 2 |
| 6 | Simultaneous versus staged liver resection of synchronous liver metastases from colorectal cancer显示文摘 | Armin Thelen Sven Jonas Christoph Benckert Antonino Spinelli Enrico Lopez-H?nninen Birgit Rudolph Ulf Neumann Peter Neuhaus | 2007 | International Journal of Colorectal Disease2007，，10： | 2 |
| 7 | Transfomling growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinomacells显示文摘 | Benckert C Jonas S Cramer T | 2003 | Cancer Res2003，163，： | 1 |
| 8 | Simultaneous versus staged liver resection of synchronous liver metastases from colorectal canc- er显示文摘 | Thelen A Jonas S Benckert C | 2007 | Int J Colorectal Dis2007，22，10： | 1 |
| 9 | Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells显示文摘 | Benckert C Jonas S Cramer T | 2003 | Cancer Res2003，63，5： | 1 |
| 10 | Liver resection for metastatic gastric cancer显示文摘 | Thelen A Jonas S Benckert C | 2008 | Eur J Surg Oncol2008，34，12： | 1 |
| 11 | VEGF-D promotes tumor growth and lymphatic spread in a mouse model of hepatocellular carcinoma显示文摘 | THELEN A SCHOLZ A BENCKERT C | 2008 | Int J Cancer2008，122，11： | 1 |
| 12 | Radical surgery for hilar cholangiocarcinoma显示文摘 | Jonas S Benckert C Thelen A | | 0，，03： | 1 |
| 13 | Impact of mierovessel density on lymph node metastasis and survival after curative resection of pancreatic cancer显示文摘 | BENCKERT C THELEN A CRANER T | 2012 | Surg Today2012，42，2： | 1 |
| 14 | VEGF-D promotes tumor gro-wth and lymphatic spread in a mouse model of hepatocellular carcinoma显示文摘 | Thelen A Scholz A Benckert C | 2008 | Int J Cancer2008，122，11： | 1 |
| 15 | Repeat liver reseetion fir recurrent liver metastases from colorectal cancer显示文摘 | Thelen A Jonas S Benckert C | 2007 | Eur J Surg onco12007，33，3： | 1 |
| 16 | VEGF-D promotes tumor growth and lymphatic spreadin a mouse model of hepatocellular carcinoma显示文摘 | Thelen A Scholz A Benckert C | 2008 | Int J Cancer2008，122，11： | 1 |
| 17 | Radical surgery for hilar cholangiocarcinoma显示文摘 | Jonas S Benckert C Thelen A et a1 | 2008 | Eur J Surg Oncol2008，34，3： | 1 |
| 18 | Transforming growth factor β 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells 显示文摘 | Benckert C Jonas S | 2003 | Cancer Res2003，63，5： | 1 |
| 19 | Impact of mi- crovessel density on lymph node metastasis and survival after curative resection of pancreatic cancer 显示文摘 | Benckert C Thelen A Cramer T | 2012 | Surg To- day2012，42，2： | 1 |
| 20 | Radical surgery for hilar Cholangiocarcinoma显示文摘 | Jonas S Benckert C Thelen A | 2008 | Eur J Surg Oncol2008，34，3： | 1 |
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