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5篇 您的检索式：作者名="Benjamin F Matthews"

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		题名	作者	年代	出处	被引量
	1	Consecutive fecal calprotectin measurements for predicting relapse in pediatric Crohn's disease patients显示文摘BACKGROUND Asymptomatic children with Crohn's disease(CD) require ongoing monitoring to ensure early recognition of a disease exacerbation.AIM In a cohort of pediatric CD patients, we aimed to assess the utility of serial fecal calprotectin measurements to detect intestinal inflammatory activity and predict disease relapse.METHODS In this prospective longitudinal cohort study, children with CD on infliximab therapy in clinical remission were included. Fecal calprotectin levels were assessed at baseline and at subsequent 2-5 visits. Clinical and biochemical disease activity were assessed using the Pediatric Crohn's Disease Activity Index, Creactive protein and erythrocyte sedimentation rate at baseline and at visits over the following 18 mo.RESULTS 53 children were included and eighteen patients(34%) had a clinical disease relapse during the study. Baseline fecal calprotectin levels were higher in patients that developed symptomatic relapse [median(interquartile range), relapse 723μg/g(283-1758) vs 244 μg/g(61-627), P = 0.02]. Fecal calprotectin levels > 250μg/g demonstrated good predictive accuracy of a clinical flare within 3 mo(area under the receiver operator curve was 0.86, 95% confidence limits 0.781 to 0.937).CONCLUSION Routine fecal calprotectin testing in children with CD in clinical remission is useful to predict relapse. Levels > 250 μg/g are a good predictor of relapse in the following 3 mo. This information is important to guide monitoring standards used in this population.	Alice Jane Foster Matthew Smyth Alam Lakhani Benjamin Jung Rollin F Brant Kevan Jacobson	2019	World Journal of Gastroenterology2019，25，10：	3
	2	Ecological correlates of seed desiccation tolerance in tropical African dryland trees 显示文摘	Hugh W P Matthew I D Benjamin J F	2004	American Journal of Botany2004，91，6：	1
	3	Identification of Heterodera glycines ( soybean Cyst Nematode ) cDNA Sequences with High Identity to those of Caenorhabditis elegans Having Lethal Mutant or RNAi Phenotypes 显示文摘	Nadim W Alkharouf Vincent P Klink Benjamin F Matthews	2007	Experimental Parasitology2007，115，：	1
	4	Chronic exogenous kisspeptin administration accelerates gonadal development in basses of the genus Morone显示文摘	Benjamin H B Adam F S Matthew E		0，，162：	1
	5	Online analytical processing(OLAP) :A fast and effective data mining tool for gene expression databases 显示文摘	Nadim W Alkharouf Curtis Jamison D Benjamin F Matthews	2005	Journal of Biomedicine and Biotechnology2005，，2：	1

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