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| 1 | n-3高不饱和脂肪酸对黑鲷幼鱼生长及脂肪代谢的影响显示文摘研究了饲料中不同水平n-3 HUFA(0.79%,0.83%,0.85%,0.88%,0.92%,0.94%;DHA/EPA=2.8/1)对黑鲷幼鱼生长及脂肪代谢的影响。结果显示:(1)黑鲷幼鱼肝体指数(HSI)及腹脂率(IPF ratio)随饲料中n-3 HUFA含量的增加而减小,且于0.92%和0.94%组时显著低于其他各组;脂肪细胞直径呈减小趋势,其中0.94%组显著小于0.85%组;肌肉脂肪含量受n-3 HUFA的影响显著,于0.88%组时达到最低。各组全鱼水份和脂肪含量差异不显著(P>0.05)。肝脏、肌肉及腹腔脂肪组织饱和脂肪酸(∑SFA)和C16∶0含量均随饲料n-3HUFA水平增加呈下降趋势,而∑n-3 HUFA呈显著上升趋势。各组织中DHA/EPA不受饲料脂肪酸组成的影响。以增重率为参考指标,二次回归分析结果表明,黑鲷幼鱼[(8.08±0.09)g]获得最佳增重时对饲料中n-3 HUFA的需要量为0.87%DM;(2)黑鲷幼鱼肝脏脂肪酸合成酶(FAS)活性及基因表达水平均在n-3 HUFA>0.92%时有显著下降(P<0.05);腹腔脂肪激素敏感脂肪酶(HSL)活性及基因表达水平均随饲料中n-3 HUFA的添加呈升高趋势(P<0.05),且高含量n-3 HUFA(0.94%)可使HSL活性增加近一倍。结果表明,饲料中n-3HUFA通过同步调控脂肪合成与分解两个过程影响黑鲷幼鱼脂肪代谢。 | 马晶晶 邵庆均 许梓荣 周凡 钟观运 宋文新 Owari Ngandeali Bergo | 2009 | 水产学报2009,33,4: | 26 |
| 2 | Silencing RhoA inhibits migration and invasion through Wnt/β-catenin pathway and growth through cell cycle regulation in human tongue cancer显示文摘地岬相当或相同的事物基因家庭成员 A (RhoA ) 作为肿瘤的一个批评管理者被识别了好攻击的行为。在 thisstudy,我们在位于有鳞的细胞 carcinomaof 舌头(TSCC ) 的生长,移植,和侵略下面的机制估计了 RhoA 的角色。TSCC 房间线 SCC-4 和 CAL27 击倒的稳定的 RhoA 用 Lentiviral transfection 被完成。房间移植,侵略,和房间增长上的 RhoA 弄空的 Theeffects 是坚定的。TSCC 房间线上的可能的位于决定 Galectin-3 (Gal-3 ) 的表示下面 mechanismof RhoA 弄空被也评估,在 vivo 的 -catenin, andmatrix metalloproteinase-9 (MMP-9 ) 。同时, TSCC 生长的内在的机制被 cyclin D1/2 的分析学习, p21 CIP1/WAF1 , 和 p27 Kip1 蛋白质层次。Immunohistochemical 评价被执行进一步证明 Gal-3 和 -catenin expression.We 的改变发现了那,在与在舌头的人的 TSCC 房间注射的老鼠, RhoA 层次与在正常纸巾的那些相比在主要肿瘤和 metastasizedlymph 节点是更高的。RhoA 的 Silencing 显著地减少了肿瘤生长, Gal-3 的 decreasedthe 层次, -catenin, MMP-9,和 cyclin D1/2,并且增加了 p21 CIP1/WAF1 和 p27 Kip1 。在 vitro, RhoA 击倒也导致了房间移植,侵略,和增长的抑制。我们的数据建议 RhoA 由通过分别地通过房间周期规定表明小径 andcell 增长的 Wnt/-catenin 调整房间移植和侵略在 TSCC 前进起 asignificant 作用。RhoA 可能是 TSCC 的一个新奇治疗学的目标。 | Guoxin Yan Ronghai Zou Zhenggang Chen Bing Fan Zhaoyan Wang Ying Wang Xiaonan Yin Dong Zhang Lei Tong Fang Yang Weina Jiang Wensheng Fu Jiwei Zheng Martin O. Bergo Martin Dalin Jiawei Zheng Shulan Chen Jianhua Zhou | 2014 | Acta Biochimica et Biophysica Sinica2014,46,8: | 7 |
| 3 | 三种常用药物对黑鲷幼鱼的急性毒性试验显示文摘试验研究水产常用药物敌百虫、硫酸铜+硫酸亚铁合剂、高锰酸钾对黑鲷幼鱼的急性毒性。结果发现,黑鲷幼鱼对敌百虫24、48、96h的半数致死浓度分别为1.13、0.85、0.54mg/l,敌百虫对黑鲷幼鱼的安全浓度为0.14mg/l;黑鲷幼鱼对硫酸铜+硫酸亚铁合剂(5:2)24、48、96h的半数致死浓度分别为7.07、6.43、6.25mg/l,硫酸铜+硫酸亚铁合剂对黑鲷幼鱼的安全浓度为1.60mg/l;1mg/l和2mg/l的高锰酸钾在30min内对黑鲷幼鱼的行为等无明显影响。 | Owari Ngandeali Bergo 马晶晶 王鸣 邵庆均 | 2010 | 饲料工业2010,31,16: | 3 |
| 4 | Cigarette smoking increases aortic dilatation without affecting matrix metallopreteinase-9 and-12 expression in a modified mouse model of aneurysm formation 显示文摘 | Bergoeing MP Hackmann AE Ennis TL | 2007 | J Vase Surg2007,45,6: | 1 |
| 5 | Selection and identifica- tion of autochthonous potential probiotic bacteria from turbot larvae (Scophthalmus maximus) rearing units显示文摘 | Hjelm M Bergo O Riaza A | 2004 | Syst Appl Microbiol2004,27,: | 1 |
| 6 | On the physiological importance of endoproteolysis of CAAX proteins:heart-specific RCEI knockout mice develop a lethal cardiomyopathy 显示文摘 | Bergo MO Lieu HD Gavino BJ | 2004 | J Biol Chem2004,279,6: | 1 |
| 7 | Protein farnesyltransferase inhibitors and progeria显示文摘 | Meta M Yang S H Bergo M O | 2006 | Trends Mol Med2006,12,10: | 1 |
| 8 | Targeting Ras signaling through inhibition of carboxyl methylation:an unexpected property of methotrexate显示文摘 | Winter-Vann A M Kamen B A Bergo M O | 2003 | Proc Natl Acad Sci USA2003,100,11: | 1 |
| 9 | Evaluation of accelerated aging procedures of painted galvanised steels by EIS 显示文摘 | Fedrizzi L Bergo A Fanicchia M | 2006 | Eleetroehimica Aeta2006,51,89: | 1 |
| 10 | Lamin B1 is required for mouse development and nuclear integrity显示文摘 | Vergnes L Péterfy M Bergo M O | 2004 | Proc Nati Acad Sci USA2004,101,10: | 1 |
| 11 | Antioxidants accelerate lung cancer progression in mice显示文摘 | Sayin VI Ibrahim MX Larsson E Nilsson JA Lindahl P Bergo MO | 2014 | Sci Transl Med2014,6,22: | 1 |
| 12 | Absence of the CAAX endoprotease Rce1:effects on cell growth and transformation显示文摘 | Bergo MO Ambroziak P Gregory C | 2002 | Mol Cell Biol2002,22,1: | 1 |
| 13 | Targeting Ras signaling through inhibition of carboxyl methylation: an unexpected property of methotrexate显示文摘 | Winter-Vann A M Kamen B A Bergo M O | 2003 | Proc Natl Acad Sci U S A2003,100,11: | 1 |
| 14 | Endoproteolytic processing of RhoA by Rcel is required for the cleavage of RhoA by Yersiniaenterocolitiea outer protein T显示文摘 | Fueller F Bergo M O Young S G | 2006 | Infect Immun2006,74,3: | 1 |
| 15 | Phylogenetic relationships among species of Anopheles (Nyssorhynchus) (Diptera: Culicidae) based on nuclear and mitochondrial gene sequences显示文摘 | Bourke BP Foster PG Bergo ES | 2010 | Acta Trop2010,114,2: | 1 |
| 16 | Transfer of KPC-2Car-bapenemase from Klebsiella pneumoniae to Escherichia coli inapatient:first case in Europe显示文摘 | Richter SN Frasson I Bergo C | 2011 | J Clin Microbiol2011,49,5: | 1 |
| 17 | Seasonal changes in the body composition of young riverine Atlantic salmon and brown trout 显示文摘 | Bergo K Bremset G | 1998 | Journal of Fish Biology1998,52,: | 1 |
| 18 | Role of visible light in the recovery of photosystem Ⅱ structure and function from ultravio- let-B stress in higher plants显示文摘 | BERGO E SEGALLA A GIACOMETTI GM TARANTINO D SOAVE C ANDREUCCI F BARBATO R | 2003 | Journal of Experimental botany2003,54,: | 1 |
| 19 | Endovascular Treatment of Symptomatic Pulmonary Sequestration显示文摘 | Leopoldo M. Marine Francisco E. Valdes Renato M. Mertens Michel R. Bergoeing Albrecht Kramer | 2011 | Annals of Vascular Surgery2011,,5: | 1 |
| 20 | A decade lost and found: Mexico and Chile in the 1980s显示文摘 | BERGOEING R KEHOE P J KEHOE T J | 2002 | Review of Economic Dynamics2002,5,1: | 1 |