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您的检索式：作者名="Bharatkumar Patel"
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| 1 | Lepidium sativum Linn.种子的脱脂乙醇提取物体外自由基清除活性(英文)显示文摘AIM:The objective of the present study was to evaluate the antioxidant potential of the defatted ethanolic extract of the seeds of Lepidium Sativum Linn.METHODS:Different in vitro chemical assays viz.DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging,ABTS (2,2-azinobis-(3-ethylbenzothiazoline-6-sulphonate) radical scavenging,iron chelation,lipid peroxidation,super-oxide scavenging and non-enzymatic haemoglobin glycosylation assay were used.The total antioxidant capacity of the extract was determined spectrophotometrically by phosphomolybdic acid method.RESULT & CONCLUSION:The defatted lepidium seed extract showed significant free radical scavenging activity in ABTS and non-enzymatic glycosylation assays,and a moderate activity in all the other assays.IC50 of the extract in the DPPH,ABTS,iron chelation,lipid peroxidation and super oxide scavenging assays were found to be 171.13,38.64,128.94,71.39 and 206.09 μg·mL-1 respectively.The haemoglobin glycosylation assay of the extract showed a percentage scavenging of 46.60% and 74.88%,at 0.5 and 1.0 μg·mL-1,concentrations,respectively.Total antioxidant capacity of ethanolic extract of L.sativum (10 mg·mL-1) was found to be equivalent to 58.38 μg·mL-1 of ascorbic acid. | Annie Shirwaikar Bharatkumar Patel Yogesh Kamariya Vinit Parmar Saleemulla Khan | 2011 | 中国天然药物2011，9，6： | 1 |
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