|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Endoscopicultrasonographyforsurveillanceofindividualsathighriskfor pancreaticcancer显示文摘Pancreatic cancer is a highly lethal disease with a ge-netic susceptibility and familial aggregation found in 3%-16% of patients. Early diagnosis remains the only hope for curative treatment and improvement of prog-nosis. This can be reached by the implementation of an intensive screening program, actually recommended for individuals at high-risk for pancreatic cancer de-velopment. The aim of this strategy is to identify pre-malignant precursors or asymptomatic pancreatic can-cer lesions, curable by surgery. Endoscopic ultrasound (EUS) with or without fine needle aspiration(FNA) seems to be the most promising technique for early de-tection of pancreatic cancer. It has been described as a highly sensitive and accurate tool, especially for small and cystic lesions. Pancreatic intraepithelial neoplasia, a precursor lesion which is highly represented in high-risk individuals, seems to have characteristics chronic pancreatitis-like changes well detected by EUS. Many screening protocols have demonstrated high diagnostic yields for pancreatic pre-malignant lesions, allowing prophylactic pancreatectomies. However, it shows a high interobserver variety even among experienced en-dosonographers and a low sensitivity in case of chronic pancreatitis. Some new techniques such as contrast-en-hanced harmonic EUS, computer-aided diagnostic tech-niques, confocal laser endomicroscopy miniprobe andthe detection of DNA abnormalities or protein markersby FNA, promise improvement of the diagnostic yield ofEUS. As the resolution of imaging improves and as ourknowledge of precursor lesions grows, we believe thatEUS could become the most suitable method to detectcurable pancreatic neoplasms in correctly identifiedasymptomatic at-risk patients. | Lami G Biagini MR Galli A | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 8 |
| 2 | Reconstruction of parodontal tissue with chitosan显示文摘 | Muzzarelli R Biagini G Pugnaloni A | 1989 | Biomaterials1989，9，： | 1 |
| 3 | Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria 显示文摘 | BIAGINI G A VIRIYAVEJAKUL O O’NEILL P M | 2006 | Antimicrob Agents Chemother2006，50，： | 1 |
| 4 | Mitochondrial changes in-duced by natural and synthetic asbestos fibers: studies on isolated mitochondfia 显示文摘 | Bergamini C Fato R Biagini G | 2004 | Cell Mol Biol ( Noisy-le-grand )2004，50，： | 1 |
| 5 | Uhrasound enhanced detection of individual meningococcal serogroups by latex immunoassay 显示文摘 | M A Sobanski R Vince G A Biagini | 2002 | J Clin Pathol2002，55，1： | 1 |
| 6 | Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromerie protongated channels sensitive to Gd^3+显示文摘 | Babinski K Catarsi S Biagini G | 2000 | J Biol Chem2000，275，28： | 1 |
| 7 | Expression of p53 and apoptosis of tumor cells in locally advanced cervical carcinoma alter cisplatin based neoadjuvant chemotherapy显示文摘 | GarzeUi GG Biagini G Provinciali M | 1996 | Anticancer Res1996，16，5： | 1 |
| 8 | The pilocarpine model of tempo- ral lobe epilepsy显示文摘 | Curia G Longo D Biagini G | 2008 | J Neurosei Methods2008，172，2： | 1 |
| 9 | Morphological development of the human placenta in normal and complicated gestation: a quantitative and ultrastructural study显示文摘 | Biagini G Vasi V Pugnaloni A | 1989 | Gynecol Obstet Invest1989，28，2： | 1 |
| 10 | Proepileptie influence of a focal vascular lesion affecting entorhinal'cortex - CA3 connections after status epileptieus显示文摘 | Biagini G Baldelli E Longo D | 2008 | J Neuropathol Exp Neuro12008，67，7： | 1 |
| 11 | Proepileptic influence of a focal vascular lesion affecting entorhinal cortex-CA3 connections after status epilepticus 显示文摘 | Biagini G Baldelli E Longo D | 2008 | Neuropathol Exp Neurol2008，67，7： | 1 |
| 12 | Tailoring biomaterial compatibility: in vivo tissue response versus in vitro cell behavior显示文摘 | Mattioli - Belmonte M Giavaresi G Biagini G | 2003 | Int J Artff Organs2003，26，12： | 1 |
| 13 | Liver fibrosis and extraellular matrix 显示文摘 | Biagini G Ballardini G | 1989 | J Hepatol1989，8，1： | 1 |
| 14 | Correlation between, clini- cal, biochemical, color Doppler Ultrasound thyroid parameters, and CXCL-10 in autoimmune thyroid diseases 显示文摘 | Corona G Biagini C Rotondi M | 2008 | Endoer J2008，55，2： | 1 |
| 15 | The pilocarpine model of temporal lobe epilepsy 显示文摘 | Curia G Longo D Biagini G | 2008 | J Neurosci Methods2008，172，2： | 1 |
| 16 | Evolution of the hydrogenosome显示文摘 | BIAGINI G A FINLAY D G LLOYD D | 1997 | FEMS Microbiology Letters1997，100，： | 1 |
| 17 | Brain-derived neurotrophic factor superinduction parallels anti-epileptic--netroprotective treatment in the pilocarpine epilepsy model显示文摘 | Biagini G Avoli M Marcinkiewicz J | 2001 | J Neurochem2001，76，6： | 1 |
| 18 | Reconstruction of parodontal tissue with ehitosan显示文摘 | Muzzarelli R Biagini G Pugnaloni A | 1989 | Biomaterials1989，10，9： | 1 |
| 19 | The pilocarpinemodel of temporal lobe epilepsy显示文摘 | Curia G Longo D Biagini G | 2008 | J Neurosci Methods2008，172，2： | 1 |
| 20 | Brain-derived neuro- trophic factor superinduction parallels anti-epileptic-neuroprotective treatment in the pilocarpine epilepsy model 显示文摘 | Biagini G Avoli M Mareinkiewicz J | 2001 | J Neurochem2001，76，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员