1篇
您的检索式：作者名="Bianfeng Zhao"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 乳腺浸润性导管癌组织中HMGB1表达的临床意义(英文)显示文摘Objective: Exploring the clinical signification of high-mobility group box 1 protein(HMGB1) expression in infiltrating ductal carcinoma(IDC) breast tissue. Methods: The expression of HMGB1 protein in IDC breast tissue was detected by immunohistochemistry, and the relations among size of tumour, lymph node metastasis, clinical staging, estrogen receptor(ER), progesterone receptor(PR) and human epidermal growth factor receptor 2(HER-2) were also analyzed. Results: Fortysix cases out of 60 cases of IDC breast tissue showed positive or strong positive HMGB1 expression(76.67%), statistical significance was observed between HMGB1 expression with clinical staging(P < 0.01), lymph node metastasis(P < 0.01), breast cancer ER(P < 0.05) and HER-2(P < 0.05), however same conclusion can not be drawn between HMGB1 with either size of tumour or PR expression(P > 0.05) in IDC breast tissue. Spearman analysis showed negative correlation between HMGB1 expression and ER, and positive correlation between HMGB1 expression and clinical staging, lymph node metastasis together with HER-2. Conclusion: It's promising that HMGB1 expression in IDC tissue can be one of biological indicators of poor prognosis. | Baoping Chang Xiao Wang Songsou Gao Bianfeng Zhao Wanli Wang Shaohua Yang Qian Chu Shiying Yu | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员