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| 1 | LncRNA NEAT1 promotes colorectal cancer cell proliferation and migration via regulating glial cell-derived neurotrophic factor by sponging miR-196a-5p显示文摘Colorectal cancer (CRC)is the one of the most common malignant tumors worldwide.Recent years,widespread long non-coding RNAs (IncRNAs)have been discovered and are known to regulate gene expression in cancers.However,the roles and underlying mechanisms of IncRNA in CRC remain largely unclear.Here,we firstly revealed that repression of IncRNA nuclear paraspeckle assembly transcript 1 (NEAT1)inhibited cell proliferation and migration in HCT116.cells and overexpression of NEAT1 promoted cell proliferation and migration in SW480 cells using CCK8 assay and transwell assay.Then,we found that suppression of NEAT1 increased the miR- 196a-5p expression in HCT116 cells,while elevation of NEAT1 decreased the miR-196a-5p expression in SW480 cells using qPCR assay.Furthermore,miR-196a-5p could bind to the predicted binding site of NEAT1.We then found that miR-196a-5p was involved in the role of NEAT1 in CRCs.In addition,we demonstrated that miR-196a-Sp mimics inhibited the glial cell-derived neurotrophic factor (GDNF)expression in HCT116 cells and meanwhile,miR-196a-5p inhibitor promoted GDNF expression in SW480 cells using qPCR and western blot analysis.Then,we proved that miR-196a- 5p exerted its function via regulating GDNF expression in CRCs.Ultimately,our study demon- strated that NEAT1 exerted its role via miR-196a-5p/GDNF axis in CRCs.In summary,this work provided the first evidence of a NEAT1/miR-196a-5p/GDNF regulatory pathway in CRC. | Feng Zhong Wei Zhang Yang Cao Qian Wen Yue Cao Bidan Lou Jinxiang Li Wenying Shi Yinghan Liu Rong Luo and Cheng Chen | 2018 | Acta Biochimica et Biophysica Sinica2018，50，12： | 5 |
| 2 | Effect of 'Yang-warming and kidney essence-replenishing' herbal paste on cold-related asthma exacerbation显示文摘OBJECTIVE: To observe the effect of 'Yang-warming and kidney essence-replenishing' herbal paste on cold-related asthma exacerbation. METHODS: One hundred and fifty one patients with moderate to severe persistent asthma were randomly divided into a treatment group (n=74) and a control group (n=69). Both groups were given basic treatment according to the Global Initiative for Asthma scheme. The treatment group was also treated with herbal paste in the winter. The frequency of asthma exacerbation, cold and cold-re-lated asthma exacerbation, scores of the asthma control test (ACT), and kidney-deficiency syndrome during the one-year follow-up in each group were recorded. RESULTS: Compared with the control group, the onset frequencies of catching cold, asthma exacerbation, cold-related asthma exacerbation, and kidney-deficiency syndrome score were significantly reduced. There was no significant difference in scores of ACT between the two groups. CONCLUSION: 'Yang-warming and kidney essence-replenishing' herbal paste could reduce cold-related asthma exacerbation. | Binqing Tang Kehua Shi Xiaoqi Li Hongchang Wang Hong Fang Bidan Xiong Yingen Wu | 2013 | Journal of Traditional Chinese Medicine2013，33，4： | 3 |
| 3 | Conjugated Polyrotaxanes in Corporating Mono-ordivalent Copper Complexes 显示文摘 | VIDAL P L DIVISIA-BLOHORN B BIDAN G | 1999 | Inorg Chem1999，38，： | 1 |
| 4 | Poly(2-propylaniline) : An electroactive polymer, soluble in organic medium in the reduced state 显示文摘 | Bidan G Genies E M Penneau J F | 1989 | Journal of Electroanalytical Chemistry1989，271，12： | 1 |
| 5 | Modification of ployaniline films with hetempolyanion: electro catalytic reduction of oxygen and protons显示文摘 | Bidan G Genies E M Lapkowski M | 1988 | Chem Sec Chem Commu1988，8，： | 1 |
| 6 | Poly(2-propylaniline): an electroactive polymer, soluble in organic medium in the reduced state显示文摘 | Bidan G Genies E M Penneau J F | 1989 | J Electroanal Chem1989，271，12： | 1 |
| 7 | 显示文摘 | Bidan G Billon M Livache T | 1999 | Synthetic Met1999，102，13： | 1 |
| 8 | Low-complexity high-rate Reed-Solomon block Turbo codes 显示文摘 | ZHOU R BIDAN R L PYNDIAH R | 2007 | IEEE Trans on Comm2007，55，9： | 1 |
| 9 | Les Schizosaccharomyces en Oenologie显示文摘 | Bidan P Meyer J P Schaeffer A | 1974 | Bull O I V1974，47，： | 1 |
| 10 | Electroconducting conjugated polymers:New sensitive matrices to build up chemical or electrochemical sensors:a review显示文摘 | Bidan G | 1992 | Sensor Actuat B1992，6，： | 1 |
| 11 | 查看详情显示文摘 | Buffenoir A Bidan G Chalumeau L | | 0，，： | 1 |
| 12 | Mo1221 Adalimumab Maintains Remission for Up to 4 Years in Patients With Ulcerative Colitis显示文摘 | Jean-Frederic Colombel William Sandborn Subrata Ghosh Douglas C. Wolf Remo Panaccione Brian G. Feagan Walter Reinisch Anne Robinson Andreas Lazar Martina Kron Bidan Huang Roopal Thakkar | | Gastroenterology0，，5： | 1 |
| 13 | ELECTRODE MODIFIED BY SULFONATED CALIXARENES IMMOBILIZED INTO A POLYPYRROLE FILM - A STEP TOWARDS NEW ION-SENSITIVE LAYERS显示文摘 | Bidan G Niel M A | | 0，，： | 1 |
| 14 | Increased Risk of Malignancy with Adalimumab Combination Therapy, Compared to Monotherapy, for Crohn’s Disease显示文摘 | Mark T. Osterman William J. Sandborn Jean-Frederic Colombel Anne M. Robinson Winnie Lau Bidan Huang Paul F. Pollack Roopal B. Thakkar James D. Lewis | 2013 | Gastroenterology2013，，： | 1 |
| 15 | Conjugated polyrotaxanes incorporating mono- or divalent copper complexes显示文摘 | Vidal P L Divisia-Blohorn B Bidan G | 1999 | Inorg Chem1999，38，： | 1 |
| 16 | New Nanocornposite Materials Made of an Insulating Matrix Conducting Fillers: Process and Properties显示文摘 | Flandin L Bidan G Brechet Y etc | 2000 | Polymer Composites2000，21，2： | 1 |
| 17 | Safety and Efficacy of Adalimumab for Moderate to Severe Crohn’s Disease in Children显示文摘 | Jeffrey S. Hyams Anne Griffiths James Markowitz Robert N. Baldassano William A. Faubion Richard B. Colletti Marla Dubinsky Jaroslaw Kierkus Joel Rosh Yaqin Wang Bidan Huang Barry Bittle Michael Marshall Andreas Lazar | 2012 | Gastroenterology2012，，2： | 1 |
| 18 | Positivity rates and performances of immunochemical faecal occult blood tests at different cut-off levels within a colorectal cancer screening programme显示文摘 | Jean Faivre Vincent Dancourt Sylvain Manfredi Bernard Denis Gérard Durand Isabelle Gendre Jeanne Marie Bidan Christine Jard Romuald Levillain Sylvie Jung Jér?me Viguier Etienne Dorval | 2012 | Digestive and Liver Disease2012，，8： | 1 |
| 19 | Part I: A comparative electrochemical study of transition metal substituted Dawson type heteropoiyanions 显示文摘 | McCormac T Fabre B Bidan G | 1997 | J Electroanal Chem1997，425，12： | 1 |
| 20 | 显示文摘 | Bidan G Guillerez S Sorokin V | 1995 | Adv Mater1995，7，： | 1 |
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