|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 中庭式地铁车站地震响应振动台试验显示文摘中庭式地铁车站因用大量横梁取代楼板来形成中庭大开口(顶层和中层楼板的开口率均超过50%),且站厅层无柱,站台层采用宽高比达7.5的薄壁柱,车站结构抵抗横向变形比如地震作用的能力,成为值得担忧的一个问题。为此,针对埋置于人工模型土中的中庭式地铁车站模型,进行了一系列1g振动台试验,探究中庭式地铁车站结构的地震响应特征,以及地震动强度对土和车站动力响应的影响规律。试验结果表明:地震作用下,站厅层横梁两端的峰值动拉应变最大,站厅层横梁两端为抗震最薄弱环节;中庭式车站侧墙与邻近土体的加速度响应差异在不同埋深处表现不同;地震动强度对车站结构和场地的地震响应均影响显著;随地震动强度增加,场地的卓越频率变得越不显著,其加速度傅里叶谱的主要幅值段趋向坐落于更宽的频带内;随地震动强度增加,顶板埋深处土和侧墙加速度放大系数差异逐渐递减;随地震动强度增加,侧墙上峰值动土正应力分布形状可能发生变化,且沿车站左、右侧墙的峰值动土正应力呈非对称分布;水平横向地震动输入下,中庭式车站存在摇摆运动,且车站顶板的竖向加速度随水平输入地震动强度的增加而增大。试验结论有助于更好地认识中庭式地下结构的地震响应规律,为类似结构的抗震设计提供参考。 | 张志明 禹海涛 袁勇 赵慧玲 BILOTTA Emilio | 2021 | 中国公路学报2021，34，5： | 6 |
| 2 | Glycemia management in critical care patients显示文摘Over the last decade, the approach to clinical management of blood glucose concentration (BGC) in critical care patients has dramatically changed. In this editorial, the risks related to hypo, hyperglycemia and high BGC variability, optimal BGC target range and BGC monitoring devices for patients in the intensive care unit (ICU) will be discussed. Hypoglycemia has an increased risk of death, even after the occurrence of a single episode of mild hypoglycemia (BGC < 80 mg/dL), and it is also associated with an increase in the ICU length of stay, the major determinant of ICU costs. Hyperglycemia (with a threshold value of 180 mg/dL) is associated with an increased risk of death, longer length of stay and higher infective morbidity in ICU patients. In ICU patients, insulin infusion aimed at maintaining BGC within a 140-180 mg/dL target range (NICE-SUGAR protocol) is considered to be the state-of-the-art. Recent evidence suggests that a lower BGC target range (129-145 mg/dL) is safe and associated with lower mortality. In trauma patients without traumatic brain injury, tight BGC (target < 110 mg/dL) might be associated with lower mortality. Safe BGC targeting and estimation of optimal insulin dose titration should include an adequate nutrition protocol, the length of insulin infusion and the change in insulin sensitivity over time. Continuous glucose monitoring devices that provide accurate measurement can contribute to minimizing the risk of hypoglycemia and improve insulin titration. In conclusion, in ICU patients, safe and effective glycemia management is based on accurate glycemia monitoring and achievement of the optimal BGC target range by using insulin titration, along with an adequate nutritional protocol. | Federico Bilotta Giovanni Rosa | 2012 | World Journal of Diabetes2012，3，7： | 5 |
| 3 | Understanding the influence of suspended solids on water quality and aquatic biota显示文摘 | G.S. Bilotta R.E. Brazier | 2008 | Water Research2008，，12： | 2 |
| 4 | Bond behavior of FRP NSM systems in concrete elements显示文摘 | Francesca Ceroni Marisa Pecce Antonio Bilotta Emidio Nigro | 2011 | Composites Part B2011，，2： | 2 |
| 5 | Intensive insulin therapy after severe traumatic brain injury: A randomized clinical trial 显示文摘 | Federico Bilotta Remo Carramia Ibolja Cemak | 2008 | Neurocritical Care2008，29，： | 1 |
| 6 | 'Anesthesia'for awake neurosurgery显示文摘 | Bilotta F Rosa G | 2009 | Curr Opin Anaesthesiol2009，22，5： | 1 |
| 7 | Association of serum vitamin D level with diabetic polyneuropathy 显示文摘 | Chaychi L Mackenzie T Bilotta D | 2011 | Med Pract Rev2011，2，1： | 1 |
| 8 | Cardiovascu- lar effects of intravenous propofol administered at two infusion rate a transthoracic echocardiographic study 显示文摘 | Bilotta F Fiorani L La Rosa I | 2001 | Anaesthesia2001，56，3： | 1 |
| 9 | Intensive insulin therapy after severe traumatic brain injury: a randomized clinical trial显示文摘 | Bilotta F Caramia R Cernak I | 2008 | Neurocrit Care2008，9，2： | 1 |
| 10 | Safety and efficacy of intensive insulin therapy in critical neurosurgical paients显示文摘 | Bilotta F Caramia R Paoloni FP | 2009 | Anesthesiology2009，110，3： | 1 |
| 11 | Bond behavior of FRP NSM systems in concrete elements 显示文摘 | Francesca Ceroni Marisa Pecce Antonio Bilotta | 2012 | Composites: PartB2012，43，： | 1 |
| 12 | Inten- sive Insulin Therapy After Severe Traumatic Brain Iniury A Randomiz ed 显示文摘 | Federico Bilotta Remo Caramia Ibolja Cernak | 2008 | Clinical Trial Neuroerit Care2008，9，2： | 1 |
| 13 | A gallery of Chua Attractors:Part I显示文摘 | Bilotta E Pantano P Stmnges F | 2007 | Int J Bifur Chaos2007，17，1： | 1 |
| 14 | Object-oriented Analysis Applied to High Resolution Satellite Data显示文摘 | Barrile V Bilotta G | 2008 | WSEAS Transactions on Signal Processing2008，4，3： | 1 |
| 15 | Bond efficiency of EBR and NSM FRP systems for strengthening concrete members 显示文摘 | Bilotta A Ceroni F Di Ludovico M | 2011 | Jour- nal of Composite for Construction2011，15，7： | 1 |
| 16 | The effect of inten- sive insulin therapy on infection rate, vasospasm, neurologic outcome, and mortality in neurointensive care unit after in- tracranial aneurysm clipping in patients with acute subarach- noid hemorrhage: a randomized prospective pilot trial 显示文摘 | Bilotta F Spinelli A Giovannini F | 2007 | J Neurosurg Anesthesiol2007，19，3： | 1 |
| 17 | Esmolol blunts postoperative hemodynamic changes after propofol-remifentanil total intravenous fast-track neuroanesthesia for intracranial surgery显示文摘 | Bilotta F Lam A M Doronzio A | 2008 | J Clin Anesth2008，20，6： | 1 |
| 18 | Expression of matrix metalloproteinase-11 is increased under conditions of insulin resistance显示文摘AIM To investigate matrix metalloproteinase-11(MMP-11) expression in adipose tissue dysfunction, using in vitro and in vivo models of insulin resistance.METHODS Culture of mouse 3T3-L1 preadipocytes were induced to differentiation into mature 3T3-L1 adipocytes. Cellular insulin resistance was induced by treating differentiated cultured adipocytes with hypoxia and/or tumor necrosis factor(TNF)-α, and transcriptional changes were analyzed in each condition thereafter. For the in vivo studies, MMP-11 expression levels were measured in white adipose tissue(WAT) from C57BL/6J mice that underwent low fat diet or high-fat feeding in order to induce obesity and obesity-related insulin resistance. Statistical analysis was carried out with GraphP ad Prism Software.RESULTS MMP-11 m RNA expression levels were significantly higher in insulin resistant 3T3-L1 adipocytes compared to control cells(1.46±0.49vs0.83±0.21, respectively;P<0.00036). The increase in MMP-11 expression was observed even in the presence of TNF-α alone(3.79±1.11vs1±0.17, P<0.01) or hypoxia alone(1.79±0.7vs0.88±0.1, P<0.00023). The results obtained in in vitro experiments were confirmed in the in vivo model of insulin resistance. In particular, MMP-11 m RNA was upregulated in WAT from obese mice compared to lean mice(5.5±2.8vs1.1±0.7, respectively; P<3.72E-08). The increase in MMP-11 levels in obese mice was accompanied by the increase in typical markers of fibrosis, such as collagen type Ⅵ alpha 3(Col6_α3), and fibroblast-specific protein 1.CONCLUSION Our results indicate that dysregulation of MMP-11 expression is an early process in the adipose tissue dysfunction, which leads to obesity and obesity-related insulin resistance. | Biagio Arcidiacono Eusebio Chiefari Anna Elisa Laria Sebastiano Messineo Francesco Luciano Bilotta Domenico Britti Daniela Patrizia Foti Anna Foryst-Ludwig Ulrich Kintscher Antonio Brunetti | 2017 | World Journal of Diabetes2017，8，9： | 1 |
| 19 | Postoperative delirium: risk factors, diagnosis and perioperative care显示文摘 | BILOTTA F LAURETTA M P BOROZDINA A | 2013 | Minerva Anestesiol2013，79，9： | 1 |
| 20 | Bond efficiency of EBR and NSM FRP systems for strengthening concrete members 显示文摘 | Bilotta A Ceroni F | 2011 | Journal of Composites for Construction2011，15，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员