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| 1 | Influence of infliximab on keratinoeyte apoptosis in psoriasis patients显示文摘 | Raho G Vena G A Bizzoca A | 2011 | Immuno- pharmacol Immunotoxicol2011，33，1： | 1 |
| 2 | Possible involvement of aquaporin-7 and-8 in rat testis development and sper- matogenesis显示文摘 | Giuseppe Calamita Amelia Mazzone Antonella Bizzoca | 2001 | Biochemical and Biophysical Research Communications2001，288，： | 1 |
| 3 | Transgenic mice expressing F3/contactin from the TAG-1 promoter exhibit developmentally regulated changes in the differentiation of cerebellar neurons显示文摘 | Bizzoca A Virgintino D Lorusso L | 2003 | Development2003，130，： | 1 |
| 4 | Influence of infliximab on keratinocyte apoptosis in psoriasis patients显示文摘 | Raho G Vena GA Bizzoca A | 2011 | Immunopharmacol Immunotoxicol2011，33，1： | 1 |
| 5 | Expression and im munolocalization of the aquaporin-8 water channel in rat gastrointestinal tract显示文摘 | CALAMITA G MAZZONE A BIZZOCA A | 2001 | Eur J Cell Biol2001，80，11： | 1 |
| 6 | Possible involvement of aquaporin-7 and -8 in rat testis development and spermatogene- sis显示文摘 | Calamita G Mazzone A Bizzoca A | 2001 | Bioehem Biophys Res Commun2001，288，3： | 1 |
| 7 | Role of biomechanical assessment in rotator cuff tear repair: Arthroscopic vs mini-open approach显示文摘BACKGROUND Rotator cuff(RC)tears are one of the most frequent pathologies within the shoulder girdle.Hand dominance and older age are associated with RC tears.Two different surgical procedures,the mini-open(MO)and all-arthroscopic(AA)approach,represented the standard of treatment.AIM To compare the clinical and biomechanical outcomes of two surgical techniques(AA vs MO procedure)performed to address the painful shoulder syndrome with partial or total supraspinatus tendon tear.METHODS Eighty-eight participants,50 following RC repair with AA and 38 with MO approach,were recruited in the present cross-sectional case-control study(ORTHO-SHOULDER,Prot.0054602).All patients underwent postoperative clinical evaluation for pain(Visual analogic scale),impairment,and disability(disability of the arm,shoulder,and hand)and limitation in daily activity(Constant-Murley score).Patients’shoulder mobility was also assessed in our Laboratory of Functional Movement through a wearable inertial sensor and surface electromyography to monitor kinematics and muscle activity during the movement on the frontal(abduction/adduction)and sagittal(flexion-extension)planes.RESULTS No statistically significant differences between the two procedures were observed in either main clinical score or range of motion.A significant increase in velocity during the movement execution and a higher contribution of upper trapezius muscles were found in the AA group compared with MO patients.CONCLUSION In terms of clinical scores,our findings were in line with previous results.However,the use of technology-based assessment of shoulder mobility has revealed significant differences between the two techniques in terms of mean velocity and pattern of muscle activation. | Giuseppe Solarino Ilaria Bortone Giovanni Vicenti Davide Bizzoca Michele Coviello Giuseppe Maccagnano Biagio Moretti Fabio D'Angelo | 2021 | World Journal of Orthopedics2021，12，12： | 1 |
| 8 | Possible involvement of aquaporin-7 and -8 in rat testis development and spermatogenesis显示文摘 | Calamita G Mazzone A Bizzoca A | 2001 | Biochem Biophys Res Commun2001，288，： | 1 |
| 9 | Expression and immunolocalization of the aquaporin-28 water channel in rat gastro intestinal tract 显示文摘 | Calamita G Mazzone A Bizzoca A | 2001 | Eur J Cell Bio2001，80，11： | 1 |
| 10 | Influence of infliximab on keratinocyte apoptosis in psoriasis patients 显示文摘 | Raho G Vena GA Bizzoca A | 2011 | Immunopharmacol Immunotoxicol2011，33，： | 1 |
| 11 | Possible involvement of aquaporin-7 and -8 in rat testis development and spermatogenesis显示文摘 | Calamita G Mazzone A Bizzoca A | 2001 | Biochem Biophys Res Commun2001，288，3： | 1 |
| 12 | F3/contactin promotes hippocampal neurogenesis, synaptic plasticity and memory in adult mice显示文摘 | Puzzo D Bizzoca A Privitera L | 2013 | Hippocampus2013，，： | 1 |
| 13 | F3/Contactin promotes hippocampal neurogenesis, synaptic plasticity, and memory in adult mice显示文摘 | Daniela Puzzo Antonella Bizzoca Lucia Privitera Dario Furnari Salvatore Giunta Francesco Girolamo Marco Pinto Gianfranco Gennarini Agostino Palmeri | 2013 | Hippocampus2013，，12： | 1 |
| 14 | Total hip arthroplasty following the failure of intertrochanteric nailing:First implant or salvage surgery?显示文摘BACKGROUND Proximal femur fractures,including both intracapsular(femoral neck fractures)and extracapsular fractures(intertrochanteric femoral fractures,IFFs),affect around 1.5 million people per year worldwide.Mechanical failures of intertrochanteric nailing in IFFs could be managed with revision total hip arthroplasty(THA).AIM To describe the surgical complexity and the procedure-related complication rates in patients with trochanteric nailing failure and treated with THA.METHODS Patients referred to our level I trauma center between April 2012 and July 2018 with failed cephalomedullary nailing following trochanteric fractures were retrospectively recruited.All patients underwent a salvage surgical procedure,i.e.,cephalomedullary nail removal and conversion to THA.The same surgical and anesthesiology team performed the surgical procedures under spinal anesthesia.All patients underwent clinical and radiographic follow-ups for at least 24 mo.Complications and re-operations were recorded.RESULTS Seventy-four patients met the inclusion criteria(male:29;female:45;mean age:73.8-years-old;range:65-89)and were included in the current study.The average operative time was 117 min(76-192 min).The average blood loss was 585 mL(430-1720 mL).Among the 74 patients,43(58.1%)required transfusion of three or more blood units.Two patients died within the 4th d after surgery because of pulmonary embolism,and 1 patient died 9 mo after surgery due to ischemic myocardial infarction.The complication rate in the 71 patients who completed the minimum 24-mo follow-up was 22.5%.In 3 cases out of 71(4.2%)periprosthetic acetabular fracture was observed during the followup.One of these periacetabular fractures occurred intraoperatively.An intraoperative periprosthetic femur fracture was observed in 5 patients out of 71(7.0%).Four of these patients needed a re-operation to fix the fracture with plates and cerclages;in one of these patients,femoral stem revision was also necessary.In 4 patients out of 71(5.6%),an early THA dislocation was observed,whereas in 1 case(1.4%)a late THA dislocation was observed.Three patients out of 71(4.2%)developed a periprosthetic joint infection during the study follow-up.CONCLUSION The present study demonstrated that salvage options for IFF fixation failure are complex procedures with a relevant intraoperative and postoperative complication rate. | Giuseppe Solarino Davide Bizzoca Pasquale Dramisino Giovanni Vicenti Lorenzo Moretti Biagio Moretti Andrea Piazzolla | 2023 | World Journal of Orthopedics2023，14，10： | 0 |
| 15 | Natural compounds may contribute in preventing SARS-CoV-2 infection:a narrative review显示文摘Coronavirus pandemic infection is the most important health issue worldwide.Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2.To date,excluding the possibility of vaccination,against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient’s symptoms.Pharmaceutical industry is investigating effects of medicinal plants,phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral drugs.Several studies have revealed how these substances may interfere with the viral life cycle,viral entry,replication,assembly or discharge,as well as virus-specific host targets or stimulating the host immune system,reducing oxidative stress and inflammatory response.A natural compound can be used as a prophylaxis by people professionally exposed to the risk of contagion and/or positive patients not in intensive care.The aim of this paper is to perform a narrative review of current literature in order to summarize the most studied natural compounds and their modes of action. | Maria Eleonora Bizzoca Stefania Leuci Michele Davide Mignogna Eleonora Lo Muzio Vito Carlo Alberto Caponio Lorenzo Lo Muzio | 2022 | Food Science and Human Wellness2022，11，5： | 0 |
| 16 | Anterior vertebral body tethering for idiopathic scoliosis in growing children:A systematic review显示文摘BACKGROUND The management of idiopathic scoliosis(IS)in skeletally immature patients should aim at three-dimensional deformity correction,without compromising spinal and chest growth.In 2019,the US Food and Drug Administration approved the first instrumentation system for anterior vertebral body tethering(AVBT),under a Humanitarian Device Exception,for skeletally immature patients with curves having a Cobb angle between 35°and 65°.AIM To summarize current evidence about the efficacy and safety of AVBT in the management of IS in skeletally immature patients.METHODS From January 2014 to January 2021,Ovid Medline,Embase,Cochrane Library,Scopus,Web of Science,Google Scholar and PubMed were searched to identify relevant studies.The methodological quality of the studies was evaluated and relevant data were extracted.RESULTS Seven clinical trials recruiting 163 patients were included in the present review.Five studies out of seven were classified as high quality,whereas the remaining two studies were classified as moderate quality.A total of 151 of 163 AVBT procedures were performed in the thoracic spine,and the remaining 12 tethering in the lumbar spine.Only 117 of 163(71.8%)patients had a nonprogressive curve at skeletal maturity.Twenty-three of 163(14.11%)patients required unplanned revision surgery within the follow-up period.Conversion to posterior spinal fusion(PSF)was performed in 18 of 163(11%)patients.CONCLUSION AVBT is a promising growth-friendly technique for treatment of IS in growing patients.However,it has moderate success and perioperative complications,revision and conversion to PSF. | Davide Bizzoca Andrea Piazzolla Lorenzo Moretti Giovanni Vicenti Biagio Moretti Giuseppe Solarino | 2022 | World Journal of Orthopedics2022，13，5： | 0 |
| 17 | Physiologic postoperative presepsin kinetics following primary cementless total hip arthroplasty:A prospective observational study显示文摘BACKGROUND Presepsin is an emerging biomarker in the diagnosis of sepsis.In the field of orthopaedics,it could be useful in diagnosing and managing periprosthetic joint infections.AIM To define the normal postoperative presepsin plasmatic curve,in patients undergoing primary cementless total hip arthroplasty(THA).METHODS Patients undergoing primary cementless THA at our Institute were recruited.Inclusion criteria were:Primary osteoarthritis of the hip;urinary catheter time of permanence<24 h;peripheral venous cannulation time of permanence<24 h;no postoperative homologous blood transfusion administration and hospital stay≤8 d.Exclusion criteria were:The presence of other articular prosthetic replacement or bone fixation devices;chronic inflammatory diseases;chronic kidney diseases;history of recurrent infections or malignant neoplasms;previous surgery in the preceding 12 mo;diabetes mellitus;immunosuppressive drug or corticosteroid assumption.All the patients received the same antibiotic prophylaxis.All the THA were performed by the same surgical and anaesthesia team;total operative time was defined as the time taken from skin incision to completion of skin closure.At enrollment,anthropometric data,smocking status,osteoarthritis stage according to Kellgren and Lawrence,Harris Hip Score,drugs assumption and comorbidities were recorded.All the patients underwent serial blood tests,including complete blood count,presepsin(PS)and C-reactive protein 24 h before arthroplasty and at 24,48,72 and 96 h postoperatively and at 3,6 and 12-mo follow-up.RESULTS A total of 96 patients(51 female;45 male;mean age=65.74±5.58)were recruited.The mean PS values were:137.54 pg/mL at baseline,192.08 pg/mL at 24 h post-op;254.85 pg/mL at 48 h post-op;259 pg/mL at 72 h post-op;248.6 pg/mL at 96-h post-op;140.52 pg/mL at 3-mo follow-up;135.55 pg/mL at 6-mo follow-up and 130.11 pg/mL at 12-mo follow-up.In two patients(2.08%)a soft-tissue infection was observed;in these patients,higher levels(>350 pg/mL)were recorded at 3-mo follow-up.CONCLUSION The dosage of plasmatic PS concentration is highly recommended in patients undergoing THA before surgery to exclude the presence of an unknown infection.The PS plasmatic concentration should be also assessed at 72 h postoperatively,evaluate the maximum postoperative PS value,and at 96 h post-operatively when a decrease of presepsin should be found.The lack of a presepsin decrease at 96 h post-operatively could be a predictive factor of infection. | Davide Bizzoca Andrea Piazzolla Lorenzo Moretti Giovanni Vicenti Biagio Moretti Giuseppe Solarino | 2023 | World Journal of Orthopedics2023，14，7： | 0 |
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