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| 1 | Clinical translation of bioartificial liver support systems with human pluripotent stem cell-derived hepatic cells显示文摘There is currently a pressing need for alternative the-rapies to liver transplantation. The number of patients waiting for a liver transplant is substantially higher than the number of transplantable donor livers, resulting in a long waiting time and a high waiting list mortality. An extracorporeal liver support system is one possible approach to overcome this problem. However, the ideal cell source for developing bioartificial liver(BAL) support systems has yet to be determined. Recent advancements in stem cell technology allow researchers to generate highly functional hepatocyte-like cells from human pluripotent stem cells(h PSCs). In this mini-review, we summarize previous clinical trials with different BAL systems, and discuss advantages of and potential obstacles to utilizing h PSC-derived hepatic cells in clinical-scale BAL systems. | Ryoichi Sakiyama Brandon J Blau Toshio Miki | 2017 | World Journal of Gastroenterology2017，23，11： | 13 |
| 2 | 全氟取代的钛酞菁衍生物的非线性光学和光限幅性能研究显示文摘制备和研究了全氟取代的钛酞菁F_(16)PcTiO及其轴向取代衍生物F_(16)PcTiO_2PhCHO的线性和非线性光学(含光限幅)性能。与F_(16)PcTiO相比,轴向取代的钛酞菁F_(16)PcTiO_2PhCHO的Q带最大峰红移了7 nm。Z-扫描实验表明,无论在甲苯溶液中还是在氯仿溶液中,F_(16)PcTiO都展现出比F_(16)PcTiO_2PhCHO更大的非线性吸收系数和低的饱和能量密度。F_(16)PcTiO_2PhCHO在氯仿溶液中的光限幅性能要明显优于其在甲苯溶液中的光限幅性能。与高度可溶的四叔丁基取代的钛酞菁(tBu_4 PcTiO和tBu_4 PcTiO_2 PhCHO)相比,十六氟取代的钛酞菁化合物具有较强的由酞菁环间范德华力驱动的分子间相互作用,这种相互作用导致材料在有机溶剂中的溶解度降低和非线性性能(含光限幅)性能下降。 | 高丽丽 陈彧 何楠 刘莹 Wang Jun Blau W.J. | 2010 | 光学学报2010，30，4： | 10 |
| 3 | JAK2转基因骨髓造血干/祖细胞体外长期扩增调控及定向分化的研究显示文摘目的 探讨酪氨酸激酶JAK2转基因骨髓造血干 祖细胞体外长期扩增调控和定向分化潜能的可行性。方法 克隆了一个MSCV based逆转录病毒载体称作MGI F2Jak2 ,它编码一个绿色荧光蛋白 (GFP)和两个改进的FK5 0 6结合蛋白 (F36v)与JAK2组成的融合蛋白 ,F36v是二聚化化学诱导物AP2 0 187的结合位点。应用该载体转染GpE +86包装细胞株 ,将C5 7BL 6小鼠的骨髓细胞与照射过15 0 0cGy的GpE +86产毒细胞株共同培养实现基因转导。转导后的细胞在X VIVO 15培养体系中扩增 ,分为①空白对照组 ;②AP2 0 187组 ;③干细胞因子 (SCF)组 ;④AP2 0 187+SCF组。扩增的细胞用直接法标记藻红蛋白荧光素 (PE)结合的抗Sca1、c kit、CD34 、Gr1、CD1 1b、TER 119、CD4 1 、B2 2 0和CD3单克隆抗体以流式细胞仪检测 ,并进行定向分化、祖细胞集落培养和脾细胞集落形成单位 (CFU S)的研究。结果 只有AP2 0 187+SCF组可以持续地使转基因的骨髓造血干 祖细胞大量增殖 ,扩增 80d后细胞可达10 1 4倍 ,细胞倍增时间约 30h ,扩增细胞的表型为CD34 、c kit和Sca1等干细胞表面标志强阳性 ,其它细胞表面标志如Gr1、CD1 1b、TER119、CD4 1 、B2 2 0、CD3接近阴性。所扩增的细胞在不同的细胞因子组合下 ,可定向分化为粒细胞、巨噬细胞、红细胞、 | 赵声明 顾惜春 常乃柏 Tim Clackson C Anthony Blau | 2004 | 中华血液学杂志2004，25，2： | 8 |
| 4 | 铟酞菁/聚甲基丙烯酸甲酯复合物固体光限幅器性能显示文摘将在溶液中表现出优良非线性光学和光限幅性能的铟酞菁及其二聚物嵌入到非光学活性的聚甲基丙烯酸甲酯(PMMA)中,用传统的旋转涂膜法制备得到具有较高光学质量的复合物薄膜,用开孔Z-扫描方法在532nm处研究了复合物薄膜材料的线性光学和非线性光学性能.结果表明,无论是铟酞菁单体还是轴向氧桥联的铟酞菁二聚物,其PMMA复合材料的光限幅性能均显著优于相应的酞菁分子在溶液中的光限幅性能. | 刘莹 陈彧 冯苗 林楹 Doyle J.J. Blau W.J. 蔡良珍 | 2007 | 高等学校化学学报2007，28，11： | 3 |
| 5 | The role of forensic anthropology in disaster victim identification(DVI):recent developments and future prospects显示文摘Forensic anthropological knowledge has been used in disaster victim identification(DVI)for over a century,but over the past decades,there have been a number of disaster events which have seen an increasing role for the forensic anthropologist.The experiences gained from some of the latest DVI operations have provided valuable lessons that have had an effect on the role and perceived value of the forensic anthropologist as part of the team managing the DVI process.This paper provides an overview of the ways in which forensic anthropologists may contribute to DVI with emphasis on how recent experiences and developments in forensic anthropology have augmented these contributions.Consequently,this paper reviews the value of forensic anthropological expertise at the disaster scene and in the mortuary,and discusses the way in which forensic anthropologists may use imaging in DVI efforts.Tissue-sampling strategies for DNA analysis,especially in the case of disasters with a large amount of fragmented remains,are also discussed.Additionally,consideration is given to the identification of survivors;the statistical basis of identification;the challenges related to some specific disaster scenarios;and education and training.Although forensic anthropologists can play a valuable role in different phases of a DVI operation,they never practice in isolation.The DVI process requires a multidisciplinary approach and,therefore,has a close collaboration with a range of forensic specialists. | Hans H.de Boer Soren Blau Tania Delabarde Lucina Hackman | 2019 | Forensic Sciences Research2019，4，4： | 3 |
| 6 | Disaster victim identification operations with fragmented,burnt,or commingled remains:experience-based recommendations显示文摘Human-made and natural disasters can result in severely fragmented,compromised,and commingled human remains.The related disaster victim identification(DVI)operations are invariably challenging,with the state of the remains potentially precluding some identifications.Practitioners involved in these DVI operations will routinely face logistical,practical,and ethical challenges.This review provides information and guidance derived from firsthand experiences to individuals tasked with managing DVI operations with fragmented human remains.We outline several key issues that should be addressed during disaster preparedness planning and at the outset of an operation,when incident-specific strategies are developed.Specific challenges during recovery and examination of fragmented remains are addressed,highlighting the importance of experienced specialists at the scene and in the mortuary.DNA sample selection and sampling techniques are reviewed,as well as downstream effects of commingling and contamination,which can complicate reconciliation and emphasise the need for rigorous quality control.We also touch on issues that may arise during communication with families.While recommendations are provided,they are not intended as proscriptive policy but rather as an addition to the general recommendations given in the International Criminal Police Organization(INTERPOL)DVI Guide,to inform preparative discussions between government officials,judiciary,police,and forensic specialists. | Hans H.de Boer Julie Roberts Tania Delabarde Amy Z.Mundorff Soren Blau | 2020 | Forensic Sciences Research2020，5，3： | 3 |
| 7 | Fabrication and near-infrared optical responses of 2D periodical Au/ITO nanocomposite arrays显示文摘Two-dimensional(2D) periodical Au and indium tin oxide(ITO) nanocomposite arrays have been fabricated based on a self-assembled nanosphere lithography technique. A button-shaped Au nanoparticle was formed on each hollow hemisphere-shaped ITO shell. Importantly, the underlying formation mechanism during the thermal treatment has been thoroughly explored by comparing structures resulting from different deposition conditions in detail. Compared to the Au nanoparticle arrays without ITO shells, the Au/ITO nanocomposite arrays showed a stronger localized surface plasmon resonance effect and higher absorption in the near-infrared(NIR) region, benefiting from the free-electron interaction enhancement between Au and ITO. The nonlinear optical properties were investigated using a modified femtosecond intensity-scan system, and the results demonstrated Au/ITO nanocomposite arrays with a remarkable two-photon absorption saturation effect for femtosecond pulses at 1030 nm. The versatile NIR optical responses indicate the great potential of the elaborately prepared 2D periodical Au/ITO nanocomposite arrays in many applications such as solar cells, photocatalysis,and novel nano optoelectronic devices. | ZHENGYUAN BAI GUIJU TAO YUANXIN LI JIN HE KANGPENG WANG GAOZHONG WANG XIONGWEI JIANG JUN WANG WERNER BLAU LONG ZHANG | 2017 | Photonics Research2017，5，4： | 2 |
| 8 | 沉浸式AR与VR技术改变计算体验显示文摘AR、VR与MR技术极大地提升了人机交互的质量、准确度与维度。充分利用颠覆性技术趋势的首席信息官们将受益于集成化的沉浸式屏幕(integrating immersive screens),但要完全实现此项颠覆性创新,尚需数年时间。 | Brian Blau | 2018 | 电子产品世界2018，25，7： | 2 |
| 9 | The evolving concept of a stem cell: entity or function?显示文摘 | Blau HM Brazelton TR Weimann JM | | 0，，： | 2 |
| 10 | Improved Surface Properties of Polymer Materisls by Multiple Lon Beam Treatment显示文摘 | Lee E H Lewis M B Blau P J | 1991 | Mater Res1991，6，3： | 1 |
| 11 | Miniaturized antennaarrays using decoupling networks with realistic elements显示文摘 | Weber J Volmer C Blau K | 2006 | IEEE Trans Microw Theory and Techniq2006，54，6： | 1 |
| 12 | Muscle mediated gene therapy显示文摘 | Blau HM Springer ML | 1995 | N Engl J Med1995，333，23： | 1 |
| 13 | An Enriching Place显示文摘 | Heidi L Blau AIA | | 0，，11： | 1 |
| 14 | 查看详情显示文摘 | Blau W Byrne H Dennis W M | | 0，，01： | 1 |
| 15 | Carbon nanotubes and nanotube composites for nonlinear optical devices显示文摘 | Wang Jun Chen Yu Blau W J | 2009 | Journal of Materials Chemistry2009，19，40： | 1 |
| 16 | A functional conjugated polymer to process, purify and selectively interact with single wall carbon nanotubes 显示文摘 | Dalton A Blau W J Chambers G | 2001 | Synth Metals2001，121，： | 1 |
| 17 | Reduced-toxicity conditioning with fludarabine and treosulfan prior to allogeneic stem cell transplantatiOn in multiple myeloma 显示文摘 | Schmidt-Hieber M Blau IW Trenschel R | 2007 | Bone Marrow Transplant2007，39，： | 1 |
| 18 | The metabolic arm molecular bases of tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency 显示文摘 | Blau N Erlandsen H | 2004 | Mol Genet Metab2004，82，2： | 1 |
| 19 | Cerebral folate deficiency and CNS inflammatory markers in Alpers disease 显示文摘 | HASSELMANN O BLAU N RAMAEKERS V T | 2010 | MolGenet Metab2010，99，1： | 1 |
| 20 | Testing a measure of cyberloafing显示文摘 | BLAU G YANG Y WARD-COOK K | 2006 | Journal of Allied Health2006，35，1： | 1 |
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