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| 1 | Sampling survey on intellectual dis- ability in approximately 6-year-old children in China 显示文摘 | Xie ZH Bo SY Zhang XT | 2008 | J Intellect Disabil Res2008，52，12： | 1 |
| 2 | 64-slice corona'y computed tomography angiography using low tube voltage of 80 kV in sub- jects:comparative study using 120kV显示文摘 | Bo RJ Hwan SY Eun-Yonng K | 2012 | Acta Radiol2012，53，： | 1 |
| 3 | Chronotropic response to exercise testing is associated with carotid atheroselerosis in healthy middle-aged men显示文摘 | Jae SY Bo Fernhall B Heffernan KS | 2006 | Eur Heart J2006，27，8： | 1 |
| 4 | 64-slice coronary computed tomography angiography using low tube voltage of 80 kV in subiects with normal body mass indices: compara- tive study using 120 kV 显示文摘 | Bo RJ Hwan SY Eun-Young K | 2012 | Acta Radlologica2012，53，： | 1 |
| 5 | A Xanthomonas transcription activator-like effector is trapped in nonhost plants for immunity显示文摘Xanthomonas oryzae pv.oryzae(Xoo),the causal agent of bacterial leaf blight in rice,delivers transcription activator-like effector(TALE)proteins into host cells to activate susceptibility or resistance(R)genes that promote disease or immunity,respectively.Nonhost plants serve as potential reservoirs of R genes;consequently,nonhost R genes may trap TALEs to trigger an immune response.In this study,we screened 17 Xoo TALEs for their ability to induce a hypersensitive response(HR)in the nonhost plant Nicotiana benthamiana(Nb);only AvrXa10 elicited an HR when transiently expressed in Nb.The HR generated by AvrXa10 required both the central repeat region and the activation domain,suggesting a specific interaction between AvrXa10 and a potential R-like gene in nonhost plants.Evans blue staining and ion leakage measurements confirmed that the AvrXa10-triggered HR was a form of cell death,and the transient expression of AvrXa10 in Nb induced immune responses.Genes targeted by AvrXa10 in the Nb genome were identified by transcriptome profiling and prediction of effector binding sites.Using several approaches(in vivo reporter assays,electrophoretic mobility-shift assays,targeted designer TALEs,and on-spot gene silencing),we confirmed that AvrXa10 targets NbZnFP1,a C2H2-type zinc finger protein that resides in the nucleus.Functional analysis indicated that overexpression of NbZnFP1 and its rice orthologs triggered cell death in rice protoplasts.An NbZnFP1 ortholog was also identified in tomato and was specifically activated by AvrXa10.These results demonstrate that NbZnFP1 is a nonhost R gene that traps AvrXa10 to promote plant immunity in Nb. | Fazal Haq Xiameng Xu Wenxiu Ma Syed Mashab Ali Shah Linlin Liu Bo Zhu Lifang Zou Gongyou Chen | 2022 | Plant Communications2022，3，1： | 1 |
| 6 | Sampling survey on in-tellectual disability in approximately 6-year-oldchildren in China 显示文摘 | Xie ZH Bo SY Zhang XT | 2008 | Intellect Disabi1 Res2008，52，12： | 1 |
| 7 | Mutant huntingtin represses CBP,but not p300,by binding and protein degradation显示文摘 | Cong SY Pepers BA Evert BO | | 0，，01： | 1 |
| 8 | Foot deformity in charcot marie tooth disease according to disease severity显示文摘 | Joo SY Choi BO Kim DY | | 0，，04： | 1 |
| 9 | A New Discovery towards Novel Skeleton of Benzimidazole-Conjugated Pyrimidinones as Unique Effective Antibacterial Agents显示文摘A class of new potential antibacterial agents with distinctive pyrimidinone benzimidazole skeleton was developed through nucleophilic substitution and Biginelli reaction starting from urea,ethyl 4-chloroacetoacetate and various aldehydes.Some target molecules exhibited strong antibacterial activities,especially pyrimidinone benzimidazole hybrid 9e possessed the strongest inhibitory effects on the growth of E.faecalis and P.aeruginosa with a lower MIC value of 1μg/mL than norfloxacin.Moreover,compound 9e displayed strong antibiofilm capacity,low drug resistance and excellent biosafety toward human red blood cells.Further research revealed that compound 9e could disrupt membrane integrity and cause leakage of cellular components such as proteins and nucleic acids.Meanwhile,compound 9e could decrease lactate dehydrogenase activity,block cell metabolism and interact with DNA in an intercalation manner. | Xi Yang Rasheed Syed Bo Fang Cheng-He Zhou | 2022 | Chinese Journal of Chemistry2022，40，22： | 0 |
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