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| 1 | Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer显示文摘AIM To determine the frequency and risk factors for colorectal cancer(CRC) development among individuals with resected advanced adenoma(AA)/traditional serrated adenoma(TSA)/advanced sessile serrated adenoma(ASSA). METHODS Data was collected from medical records of 14663 subjects found to have AA, TSA, or ASSA at screening or surveillance colonoscopy. Patients with inflammatory bowel disease or known genetic predisposition for CRC were excluded from the study. Factors associated with CRC developing after endoscopic management of high risk polyps were calculated in 4610 such patients who had at least one surveillance colonoscopy within 10 years following the original polypectomy of the incident advanced polyp. RESULTS84/4610(1.8%) patients developed CRC at the polypectomy site within a median of 4.2 years(mean 4.89 years), and 1.2%(54/4610) developed CRC in a region distinct from the AA/TSA/ASSA resection site within a median of 5.1 years(mean 6.67 years). Approximately, 30%(25/84) of patients who developed CRC at the AA/TSA/ASSA site and 27.8%(15/54) of patients who developed CRC at another site had colonoscopy at recommended surveillance intervals. Increasing age; polyp size; male sex; right-sided location; high degree of dysplasia; higher number of polyps resected; and piecemeal removal were associated with an increased risk for CRC developmentat the same site as the index polyp. Increasing age; right-sided location; higher number of polyps resected and sessile endoscopic appearance of the index AA/TSA/ASSA were significantly associated with an increased risk for CRC development at a different site. CONCLUSION Recognition that CRC may develop following AA/TSA/ASSA removal is one step toward improving our practice efficiency and preventing a portion of CRC related morbidity and mortality. | Mohamad A Mouchli Lidia Ouk Marianne R Scheitel Alisha P Chaudhry Donna Felmlee-Devine Diane E Grill Shahrooz Rashtak Panwen Wang Junwen Wang Rajeev Chaudhry Thomas C Smyrk Ann L Oberg Brooke R Druliner Lisa A Boardman | 2018 | World Journal of Gastroenterology2018，24，8： | 5 |
| 2 | Mechanisms of glucoeorticoid action and insensitivity in airways disease 显示文摘 | Boardman C Chaehi L Gavrila A | 2014 | Pulm Pharmaeol Ther2014，29，2： | 1 |
| 3 | In situ monitoring of lime-stabilized road subgrade显示文摘 | BOARDMAN D I GLENDINNING S ROGERS C D F HOLT C C | 2001 | Transportation Research Record2001，1757，： | 1 |
| 4 | Design and the Management of Multi-institutional Research Col-laborations:The Oretical Implications from Two Case Studies显示文摘 | Corley E A Boardman P C Bozeman B | | 0，，07： | 1 |
| 5 | Atypical Squamous Cells of Undetermined Significance, Human Papillomavirus, and Cervical Intraepithelial Neoplasia 2 or 3 in Adoleseents: ASC-US, Age, and High-grade Cervieal Neoplasia 显示文摘 | Boardman LA Stanko C Weitzcn S | 2005 | Obstetrics & Gynecology2005，105，4： | 1 |
| 6 | Industry Interacti the Industry Invo Government Centrality to University- ons: University Research Centers and lvement of Academic Researchers显示文摘 | Boardman P C | 2009 | Research Policy2009，38，： | 1 |
| 7 | Charac- terization of an anti-rainbow trout (Oncorhynchus mylciss) CD3 e monoclonal antibody 显示文摘 | Boardman T Warner C Ramirez G F | 2012 | Veterinary Immunology and Immunopathology2012，145，： | 1 |
| 8 | Development of stabilization and solidification in lime-saline soil mixtures显示文摘 | BOARDMAN D l GLENDINNING S ROGERS C D F | 2001 | Geotechnique2001，50，6： | 1 |
| 9 | Soluble epidermal growth factor receptor (sEGFR) and cancer antigen 125 (CA125) as screening and diagnostic tests for epithelial ovarian cancer显示文摘 | Baron A T Boardman C H Lafky J M | 2005 | Cancer Epidemiol Biomarkers Prey2005，14，2： | 1 |
| 10 | The influences of iron (III) and lead (II) contaminants on lime-stabilized clay显示文摘 | BOARDMAN D J GLEND1NNING S ROGERS C D F | 2004 | Geoteehnique2004，54，7： | 1 |
| 11 | Factors Affecting the Stock Price Performance of Share Issue Privatizations显示文摘 | Boardman A E Laurin C | 2000 | Applied Eco- nomics2000，32，11： | 1 |
| 12 | Design and the Man-agement of Multi-institutional Research Collaborations : Theoret-ical Implications from Two Case Studies 显示文摘 | Corley E A’ Boardman P C Bozeman B | 2006 | Research Policy2006，35，7： | 1 |
| 13 | Development of stabilization and solidification in lime-clay mixes显示文摘 | BOARDMAN D L GLENDINN1NG S ROGERS C D F | 2001 | Geoteehnique2001，50，5： | 1 |
| 14 | Case study of a loess collapse field trial in Kent显示文摘 | ZOURMPAKIS A BOARDMAN D I ROGERS C D F | 2006 | Quarterly Journal of Engineering Geology and Hydrogeology2006，39，2： | 1 |
| 15 | The NSF Engineering Research Centers and the University - Industry Research Revolution: A Brief History Featuring an Interview with Erich Bloch 显示文摘 | BOZEMAN B BOARDMAN C | 2004 | The Journalof Technology Transfer2004，29，34： | 1 |
| 16 | Case study of a loess collapse field trial in Kent显示文摘 | Zourmpakis A Boardman D I Rogers C D F | 2006 | Quarterly Journal of Engineering Geology and Hydrogeology2006，39，2： | 1 |
| 17 | Soluble epidermal growth factor receptor and cancer antigen 125 as screening and diagnostic tests for epithelial ovarian cancer显示文摘 | Baron A Boardman C Lafky J | 2005 | Cancer Epidemiol Biomarkers Prev2005，14，1： | 1 |
| 18 | Patterns of cerebral injury and neurodevelopmental outcomes aftersymptomatic neonatl hypoglycemia 显示文摘 | BURNS C M RUTHERFORD M A BOARDMAN J P | 2008 | Pediatrics2008，122，1： | 1 |
| 19 | A statewide smaller hospital nosocomial infection surveillance program: The first report, Victoria, Australia显示文摘 | Bennett N Boardman C Bull A | 2005 | Am J Infect Control2005，33，： | 1 |
| 20 | A branch and bound formulation to electricity distribution planning problem 显示文摘 | Boardman J T Meckiff C C | 1985 | IEEE Trans PAS1985，104，8： | 1 |
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