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| 1 | Use of High-Yielding Bioenergy Plant Castor Bean(Ricinus communis L.) as a Potential Phytoremediator for Copper-Contaminated Soils显示文摘Copper (Cu) contamination in the environment has been increased during the years with agricultural and industrial activities.Biotechnological approaches are needed for bioremediation in these areas. The aims of this study were i) to evaluate the phytoremediation capacity of the high-yielding bioenergy plant castor bean (Ricinus communis L.) in vineyard soils (Inceptisol and Mollisol) contaminated with Cu and a Cu mining waste; ii) to characterize the castor bean as a Cu phytoremediation plant; and iii) to evaluate the nutrient uptake by castor bean. Castor bean plants cultivated in soil with toxic levels of Cu for 57 d exhibited high phytomass production, a high tolerance index of roots' fresh mass and shoots' dry mass, a high level of Cu phytoaccumulation in the roots and also, a robust capacity for Cu phytostabilization. Furthermore, castor bean plants did not significantly deplete soil nutrients(such as N, P, and Mg) during cultivation. Plants cultivated in Inceptisol, Mollisol and Cu mining waste exhibited a strong potential for Cu phytoaccumulation, with values of 5 900, 3 052 and 2 805 g ha-1, respectively. In addition, the castor bean's elevated phytomass production and strong growth in Cu-contaminated soils indicated a high level of Cu phytoaccumulation and a potential application in biofuels. These findings indicate that the castor bean is a efcient hyperaccumulator of Cu and a potential candidate plant for the phytoremediation of Cu-contaminated soil. | R. ANDREAZZA L. BORTOLON S. PIENIZ F. A. O. CAMARGO | 2013 | Pedosphere2013，23，5： | 8 |
| 2 | Matched or nonmatched interventions based on the transtheoretical model to promote physical activity.A meta-analysis of randomized controlled trials显示文摘Purpose: The aim of this study was to examine whether the efficacy of transtheoretical model(TTM)-based interventions on physical activity(PA)varied according to the following criteria:(1) interventions targeted the actual stages of change(SOCs) or did not;(2) participants were selected according to their SOC or were not; and(3) its theoretical constructs(decisional balance, temptation, self-efficacy, processes of change).Methods: Thirty-three randomized controlled trials assessing TTM-based interventions promoting PA in adults were systematically identified.Results: The between-group heterogeneity statistic(Qb) did not reveal any differential efficacy either in interventions targeting the actual SOC compared with those that did not(Qb = 1.48, p = 0.22) or in interventions selecting participants according to their SOC compared with those that did not(Qb = 0.01, p = 0.91). TTM-based interventions enhanced PA behavior whether they targeted the actual SOC(Cohen's d = 0.36; 95%confidence interval(CI): 0.22–0.49) or not(d = 0.23; 95%CI: 0.09–0.38) and whether they selected their participants according to their SOC(d = 0.33; 95%CI: 0.13–0.53) or not(d = 0.32; 95%CI: 0.19–0.44). The moderators of the efficacy of TTM-based interventions were the number of theoretical constructs used to tailor the intervention(Qb = 8.82, p = 0.003), the use of self-efficacy(Qb = 6.09, p = 0.01), and the processes of change(Qb = 3.51, p = 0.06).Conclusion: TTM-based interventions significantly improved PA behavior, and their efficacy was not moderated by SOC but by the TTM theoretical constructs. | Ahmed Jerome Romain Catherine Bortolon Mathieu Gourlan Marion Carayol Emmanuelle Decker Olivier Lareyre Grégory Ninot Julie Boiché Paquito Bernard | 2018 | Journal of Sport and Health Science2018，7，1： | 2 |
| 3 | Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models显示文摘 | Yong S. Chang Jalila Adnane Pamela A. Trail Joan Levy Arris Henderson Dahai Xue Elizabeth Bortolon Marina Ichetovkin Charles Chen Angela McNabola Dean Wilkie Christopher A. Carter Ian C. A. Taylor Mark Lynch Scott Wilhelm | 2007 | Cancer Chemotherapy and Pharmacology2007，，5： | 1 |
| 4 | Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models显示文摘 | Yong S. Chang Jalila Adnane Pamela A. Trail Joan Levy Arris Henderson Dahai Xue Elizabeth Bortolon Marina Ichetovkin Charles Chen Angela McNabola Dean Wilkie Christopher A. Carter Ian C. A. Taylor Mark Lynch Scott Wilhelm | 2007 | Cancer Chemotherapy and Pharmacology2007，，5： | 1 |
| 5 | Validation of the Century model to estimate the impact of agriculture on soil organic carbon in Southern Brazil显示文摘 | Elisandra Solange Oliveira Bortolon Jo?o Mielniczuk Carlos Gustavo Tornquist Fabíola Lopes Homero Bergamaschi | 2011 | Geoderma2011，，： | 1 |
| 6 | Insight of patients and their parents into schizophrenia:Exploring agreement and the influence of parental factors显示文摘 | Macgregor A Norton J Bortolon C | 2015 | Psychiatry Res2015，228，3： | 1 |
| 7 | Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models显示文摘 | Yong S. Chang Jalila Adnane Pamela A. Trail Joan Levy Arris Henderson Dahai Xue Elizabeth Bortolon Marina Ichetovkin Charles Chen Angela McNabola Dean Wilkie Christopher A. Carter Ian C. A. Taylor Mark Lynch Scott Wilhelm | 2007 | Cancer Chemotherapy and Pharmacology2007，，5： | 1 |
| 8 | Validation of the Century model to estimate the impact of agriculture on soil organic carbon in Southern Brazil显示文摘 | Elisandra Solange Oliveira Bortolon Jo?o Mielniczuk Carlos Gustavo Tornquist Fabíola Lopes Homero Bergamaschi | 2011 | Geoderma2011，，： | 1 |
| 9 | Projecting the self into the future in individuals with schizophrenia: a preliminary cross-sectional study 显示文摘 | Raffard S Bortolon C D' Argembeau A | 2015 | Memory2015，，： | 1 |
| 10 | Grade 4 febrile neutropenia and Fournier's Syndrome associated with triple therapy for hepatitis C virus:A case report显示文摘The use of triple therapy for hepatitis C not only increases the rate of sustained virological responses compared with the use of only interferon and ribavirin(RBV) but also leads to an increased number of side effects. The subject of this study was a 53-year-old male who was cirrhotic with hepatitis C virus genotype 1 A and was a previous null non-responder. We initially attempted retreatment with boceprevir(BOC), Peginterferon and RBV, and a decrease in viral load was observed in the 8th week. In week 12, he presented with disorientation, flapping, fever, tachypnea, arterial hypotension and tachycardia. He also exhibitedleucopenia with neutropenia. Cefepime and filgrastim were initiated, and treatment for hepatitis C was suspended. A myelogram revealed hypoplasia, cytotoxicity and maturational retardation. After 48 h, he developed bilateral inguinal erythema that evolved throughout the perineal area to the root of the thighs, with exulcerations and an outflow of seropurulent secretions. Because we hypothesized that he was suffering from Fournier's Syndrome, treatment was replaced with the antibiotics imipenem, linezolid and clindamycin. After this new treatment paradigm was initiated, his lesions regressed without requiring surgical debridement. Triple therapy requires knowledge regarding the management of adverse effects and drug interactions; it also requires an understanding of the importance of respecting the guidelines for the withdrawal of treatment. In this case report, we observed an adverse event that had not been previously reported in the literature with the use of BOC. | Kelly Cristhian Lima Oliveira Emili de Oliveira Bortolon Cardoso Suzana Carla Pereira de Souza Flávia Souza Machado Carlos Eduardo Alves Zangirolami Alecsro Moreira Giovanni Faria Silva Cássio Vieira de Oliveira | 2014 | World Journal of Hepatology2014，6，6： | 0 |
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