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| 1 | Transcranial Doppler ultrasonography: From methodology to major clinical applications显示文摘Non-invasive Doppler ultrasonographic study of cerebral arteries [transcranial Doppler(TCD)] has been extensively applied on both outpatient and inpatient settings. It is performed placing a low-frequency(≤ 2 MHz) transducer on the scalp of the patient over specific acoustic windows, in order to visualize the intracranial arterial vessels and to evaluate the cerebral blood flow velocity and its alteration in many different conditions. Nowadays the most widespread indication for TCD in outpatient setting is the research of right to left shunting, responsable of so called 'paradoxical embolism', most often due to patency of foramen ovale which is responsable of the majority of cryptogenic strokes occuring in patients younger than 55 years old. TCD also allows to classify the grade of severity of such shunts using the so called 'microembolic signal grading score'. In addition TCD has found many useful applications in neurocritical care practice. It is useful on both adults and children for day-to-day bedside assessment of critical conditions including vasospasm in subarachnoidal haemorrhage(caused by aneurysm rupture or traumatic injury), traumatic brain injury, brain stem death. It is used also to evaluate cerebral hemodynamic changes after stroke. It also allows to investigate cerebral pressure autoregulation and for the clinical evaluation of cerebral autoregulatory reserve. | Antonello D'Andrea Marianna Conte Massimo Cavallaro Raffaella Scarafile Lucia Riegler Rosangela Cocchia Enrica Pezzullo Andreina Carbone Francesco Natale Giuseppe Santoro Pio Caso Maria Giovanna Russo Eduardo Bossone Raffaele Calabrò | 2016 | World Journal of Cardiology2016，8，7： | 10 |
| 2 | 难治性疼痛和高血压在急性B型主动脉夹层中的重要性:国际急性主动脉夹层登记的意见显示文摘急性B型主动脉夹层患者,可表现出对药物治疗无效的反复、难治性疼痛和(或)难治性高血压,当出现这些症状时有时可作为介入治疗的指征。研究者利用国际急性主动脉夹层登记(international registry of a-cute aortic dissection,IRAD)的资料调查难治性疼痛和(或)难治性高血压对急性B型主动脉夹层患者临床转归的影响。 | 张玲玉 叶鹏 Trimarchi S Eagle KA Nienaber CA Pyeritz RE Jonker FH Suzuki T O'Gara PT Hutchinson SJ Rampoldi V Grassi V Bossone E Muhs BE Evangelista A Tsai TT Froehlich JB Cooper JV Montgomery D Mein-hardt G Myrmel T Upchurch GR Sundt TM Issel-bacher EM | 2010 | 中华高血压杂志2010，18，12： | 4 |
| 3 | Cardiac damage in athlete's heart: When the “supernormal” heart fails!显示文摘Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological cardiac modeling in athletes is associated with normal or enhanced cardiac function, but recent studies have documented decrements in left ventricular function during intense exercise and the release of cardiac markers of necrosis in athlete's blood of uncertain significance. Furthermore, cardiac remodeling may predispose athletes to heart disease and result in electrical remodeling, responsible for arrhythmias. Athlete's heart is a physiological condition and does not require a specific treatment. In some conditions, it is important to differentiate the physiological adaptations from pathological conditions, such as hypertrophic cardiomyopathy, arrhythmogenic dysplasia of the right ventricle, and non-compaction myocardium, for the greater risk of sudden cardiac death of these conditions. Moreover, some drugs and performance-enhancing drugs can cause structural alterations and arrhythmias, therefore, their use should be excluded. | Andreina Carbone Antonello D’Andrea Lucia Riegler Raffaella Scarafile Enrica Pezzullo Francesca Martone Raffaella America Biagio Liccardo Maurizio Galderisi Eduardo Bossone Raffaele Calabrò | 2017 | World Journal of Cardiology2017，9，6： | 3 |
| 4 | Partial 17,20-desmolase and 17α-hydroxylase deficiecies in a 16 year old boy显示文摘 | Bosson D Wolter R Toppet M | 1988 | J Endocrinol Invest1988，11，： | 1 |
| 5 | The fac- tor V (FV) gene ASP79HIS polymorphism modulates FV plasma levels and affects the activated protein C resistance phenotype in presence of the FV Leiden mutation显示文摘 | Bossone A Cappucci F D'Andrea G | 2003 | Haematologica2003，88，3： | 1 |
| 6 | Biomarkers of aortic diseases显示文摘 | SUZUKI T BOSSONE E SAWAKI D | 2013 | Am Heart J2013，165，1： | 1 |
| 7 | The Diamant Dialysis cohort study: elinico-biologieal characteristics and cardiovascular genetic risk profile of incident patients 显示文摘 | Pernod G Bosson JL Golshayan D | 2004 | J nephrol2004，17，1： | 1 |
| 8 | Pulmonary arterial hypertension: the key role of eehocardiography 显示文摘 | BOSSONE E BODINI B D MAZZA A | 2005 | Chest2005，127，5： | 1 |
| 9 | Biomarkers of aortic diseases显示文摘 | Suzuki T Bossone E Sawaki D | 2013 | Am Heart J2013，165，1： | 1 |
| 10 | Echocardiography in pulmonary arterial hypertension:from diagnosis to prognosis 显示文摘 | Bossone E D Andrea A D Alto M | 2013 | J Am See Echocardiogr2013，26，： | 1 |
| 11 | Biomarkers of aortic diseases显示文摘 | Suzuki T Bossone E Sawaki D | 2013 | Am Heart J2013，，： | 1 |
| 12 | Au/Ag-cocatalyzed aldoximes to amides rearrangement under solvent- and acid-free conditions显示文摘 | RAMON R S BOSSON J GONZALE S D | 2010 | J Org Chem2010，75，： | 1 |
| 13 | Right ventrieular myocardial involve- ment in either physiological or pathological left ventricular hypertrophy: an ul- trasound speckle-tracking two-dimensional strain analysis 显示文摘 | D' Andrea A Caso P Bossone E | 2010 | Eur J Eehoear- diogt2010，11，6： | 1 |
| 14 | Association between right ventricular twodimensional strain and exercise capacity in patients with either idiopathic or ischemic dilated cardiomyopathy显示文摘 | Salerno G D’Andrea A Bossone E | 2011 | J Cardiovasc Med2011，12，9： | 1 |
| 15 | Right ven- tricular myocardial involvement in either physiological or pathological left ventricular hypertrophy: an ultra- sound speckle-tracking two-dimensional strain analysis显示文摘 | D'Andreal A Caso P Bossone E | 2010 | Eur J Echocardiogr2010，11，： | 1 |
| 16 | 1988 Serum levels of gonadotrophins and steroid hormones in the post-menopause and later life显示文摘 | Rozenberg S Bosson D Peretz A | 1988 | Maturitas1988，10，： | 1 |
| 17 | The prognostic role of the ECG in primary pulmonary hypertension显示文摘 | Bossone E Paciocco G Iarussi D Agretto A Iacono A Gillespie B W | 2002 | Chest2002，121，： | 1 |
| 18 | Pulmonary arterial hypertension:the key role of eehoeardiography 显示文摘 | Bossone E Bodini B D Mazza A Allegra L | 2005 | Chest2005，127，： | 1 |
| 19 | Biomarkers of aortic diseases显示文摘 | Suzuki T Bossone E Sawaki D | 2013 | Ame Heart J2013，165，1： | 1 |
| 20 | Echocardiography in pulmonary arterial hypertension: from diagnosis to progno- sis显示文摘 | Bossone E D'Andrea A D'Alto M | 2013 | J Am Soe Echocardiogr2013，26，1： | 1 |
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