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| 1 | Regulation of the G1 phase of the mammalian cell cycle显示文摘In any multi-cellular organism, the balance between cell division and cell death maintains a constant cell number. Both cell division cycle and cell death are highly regulated events. Whether the cell will proceed through the cycle or not, depends upon whether the conditions required at the checkpoints during the cycle are fulfilled. In higher eucaryotic cells, such as mammalian cells, signals that arrest the cycle usually act at a G1 checkpoint. Cells that pass this restriction point are committed to complete the cycle. Regulation of the GI phase of the cell cycle is extremely complex and involves many different families of proteins such as retinoblastoma family cyclin dependent kinases, cyclins, and cyclic kinase inhibitors. | DONJERKOVIC DUBRRAVKA DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD) | 2000 | Cell Research2000,10,1: | 18 |
| 2 | Activation-induced cell death in B lymphocytes显示文摘Upon encountering the antigen (Ag), the immune system can either develop a specific immune response or enter a specific state of unresponsiveness, tolerance. The response of B cells to their specific Ag can be activation and proliferation, leading to the immune response, or anergy and activation-induced cell death (AICD), leading to tolerance. AICD in B lymphocytes is a highly regulated event initiated by crosslinking of the B cell receptor (BCR). BCR engagement initiates several signaling events such as activation of PLCr, Ras, and PI3K, which generally speaking, lead to survival. However, in the absence of survival signals (CD40 or IL-4R engagement), BCR crosslinking can also promote apoptotic signal transduction pathways such as activation of effector caspases, expression of pro-apoptotic genes, and inhibition of pro-survival genes. The complex interplay between survival and death signals determines the B cell fate and, consequently, the immune response. | DONJERKOVIC DUBRAVKA, DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD, 20855. USA) | 2000 | Cell Research2000,10,3: | 6 |
| 3 | Short chain fatty acids in human large intestine, portal,hepatic, and venous blood 显示文摘 | Cummings J H Pomare E W Branch W J | 1987 | Gut1987,28,10: | 1 |
| 4 | Determination of arsenic by hydride generation inductively coupled plasma mass spectrometry using a tubular membrane gas-liquid separator显示文摘 | BRANCH S CORNS W T EBDON L | 1991 | Journal of Analytical Atomic Spectrometry1991,6,2: | 1 |
| 5 | Regulation of prohibitin expression during follicular develop-ment and atresia in the mammalian ovary显示文摘 | Thompson W E Asselin E Branch A | 2004 | Biol Reprod2004,71,1: | 1 |
| 6 | Regulation of prohibitin exprossion during follicular development and atresia in the mammalian ovary显示文摘 | Thompson W E Asselin E Branch A | 2004 | Biol Reprod2004,71,1: | 1 |
| 7 | RFLP variability in peanut (Arachis hypogaea L) cultivars and wild species显示文摘 | Kochert G Halward T Branch W D | 1991 | Theor Appl Genet1991,81,: | 1 |
| 8 | Short chain fatty acids in human large intestine, portal, hepatic and venous blood显示文摘 | Cummings J H Pomare E W Branch W J | 1987 | Gut1987,28,: | 1 |
| 9 | Fatty acid variation among U S runner-type peanut cultivars 显示文摘 | Branch W D Nakayama T Chinnan M S | 1990 | J Am Oil Chem Soc1990,67,9: | 1 |
| 10 | Antiphospholipid syndrome显示文摘 | Ruiz-Irastorza G Crowther M Branch W | 2010 | Lancet2010,376,9751: | 1 |
| 11 | Outcome of treated pregnancies in women with antiphospholipid syndrome:an update of the Utah experience显示文摘 | BRANCH D W SILVER R M BLACKWELL J L | 1992 | Obstet Gynecol1992,80,4: | 1 |
| 12 | In-network outlier detection in wireless sensor networks 显示文摘 | Branch J W Giannella C Szymanski B | 2013 | Knowledge and information systems2013,34,1: | 1 |
| 13 | Maternal thrombocytopenia in pregnancy:time for reassessment显示文摘 | SILVER R M BRANCH D W SCOTT J R | 1995 | Am J Obstet Gynecol1995,173,2: | 1 |
| 14 | Precepting hu- manism: strategies for fostering the human dimensions of care in ambulatory settings显示文摘 | Gracey C F Haidet P Branch W T | 2005 | Acad Med2005,80,1: | 1 |
| 15 | Sequence alignment for masquerade detection 显示文摘 | CouU S E Branch J W Szymanski B K | 2008 | Computational Statistics & Data Analysis2008,52,8: | 1 |
| 16 | Effect of creatine supplementation on cycle ergometer exercise in a hyperthermic environment显示文摘 | Branch J D Schwarz W D Van Lunen B | 2007 | J Strength Cond Res2007,21,1: | 1 |
| 17 | The digestion of dietary pectin in the hu- man gut and its effect on calcium absorption and large bowel function 显示文摘 | CUMMINGS J H SOUTHGATE D A T BRANCH W J | 1979 | British Journal of Nutrition1979,41,3: | 1 |
| 18 | In-network outlier de- tection in wireless sensor networks显示文摘 | Branch J W Giannella C Szymanski B | 2013 | Knowledge and Information Systems2013,34,1: | 1 |
| 19 | The antiphospholipid syndrome显示文摘 | Levine JS Branch W Rauch J | 2002 | New England Journal of Medicine2002,346,10: | 1 |
| 20 | Short chain fatty acids in human large intestine, portal, hepatic and venous blood 显示文摘 | CUMMNGS J H POMARE E W BRANCH W J | 1987 | Gut1987,28,8: | 1 |