|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Incidental non-benign gallbladder histopathology after cholecystectomy in an United Kingdom population: Need for routine histological analysis?显示文摘AIM To analyse the range of histopathology detected in the largest published United Kingdom series of cholecystectomy specimens and to evaluate the rational for selective histopathological analysis.METHODS Incidental gallbladder malignancy is rare in the United Kingdom with recent literature supporting selective histological assessment of gallbladders after routine cholecystectomy.All cholecystectomy gallbladder specimens examined by the histopathology department at our hospital during a five year period between March 2008 and March 2013 were retrospectively analysed.Further data was collected on all specimens demonstrating carcinoma,dysplasia and polypoid growths.RESULTS The study included 4027 patients.The majority(97%) of specimens exhibited gallstone or cholecystitis related disease.Polyps were demonstrated in 44(1.09%),the majority of which were cholesterol based(41/44).Dysplasia,ranging from low to multifocal high-grade was demonstrated in 55(1.37%).Incidental primary gallbladder adenocarcinoma was detected in 6 specimens(0.15%,5 female and 1 male),and a single gallbladder revealed carcinoma in situ(0.02%).This large single centre study demonstrated a full range of gallbladder disease from cholecystectomy specimens,including more than 1% neoplastic histology and two cases of macroscopically occult gallbladder malignancies.CONCLUSION Routine histological evaluation of all elective and emergency cholecystectomies is justified in a United Kingdom population as selective analysis has potential to miss potentially curable life threatening pathology. | Krashna Patel Khaled Dajani Satheesh Iype Nikolaos A Chatzizacharias Saranya Vickramarajah Susan Davies Rebecca Brais Siong S Liau Simon Harper Asif Jah Raaj K Praseedom Emmanuel L Huguet | 2016 | World Journal of Gastrointestinal Surgery2016，8，10： | 2 |
| 2 | Nuclear inclusion in oculo- pharyngeal muscular dystrophy consisit of poly(A) binding pro- tein aggregates which sequester poly (A) RNA 显示文摘 | Calado A Tome FM Brais B | 2000 | Hum Mol Genet2000，9，： | 1 |
| 3 | update on the duck market in 2001-2012 显示文摘 | I BRAI A | 2010 | TeMA-Techniques et Marches Avicoles2010，，23： | 1 |
| 4 | Combined use of an inverse method and a voltage measurement: Estimation of the arc column volume and its variations 显示文摘 | TOUMAZET J P BRAYS C LAURENT A | 2005 | Measurement Science and Technology2005，，16： | 1 |
| 5 | Response characteristics of thermolumines-cence and alanine-based dosemeters to 16 and25MeV proton beams显示文摘 | BARTOLOTTA A BARONE T L BRAI M etal | 1999 | Radiat Prot Dosi1999，85，： | 1 |
| 6 | Liquid chromatography with electrospray ion trap mass spectrometry for the determination of five azaspiracids in shellfish显示文摘 | LEHANE M BRAI'7 1A-MAGDALENA A MORONEY C | 2002 | Journal of Chromatography A2002，950，12： | 1 |
| 7 | Pregnancy - associated plasma protein A as a marker of acute coronary syndromes显示文摘 | BRAYS GENIS A CONOVER C A OVERGAARD M T | 2001 | N Engl J Med2001，345，14： | 1 |
| 8 | Updated interpretation of magnetic anomalies and seafloor spreading stages in the South China Sea:implication for the Tertiary tectonics of Southeast Asia显示文摘 | BRAIS A PATRIAT PH TAPPONNIER P | 1993 | J Geophys Res1993，98，4： | 1 |
| 9 | Colonic and anal metastases from pancreato-biliary malignancies显示文摘Pancreato-biliary malignancies often present with locally advanced or metastatic disease.Surgery is the mainstay of treatment although less than 20%of tumours are suitable for resection at presentation.Common sites for metastases are liver,lungs,lymph nodes and peritoneal cavity.Metastatic disease carries poor prognosis,with median survival of less than 3 mo.We report two cases where metastases from pancreato-biliary cancers were identified in the colon and anal canal.In both cases specific immunohistochemical staining was utilised in the diagnosis.In the first case,the pre-senting complaint was obstructive jaundice due to an ampullary tumour for which a pancreato-duodenectomy was carried out.However,the patient re-presented 4wk later with an atypical anal fissure which was found to be metastatic deposit from the primary ampullary adenocarcinoma.In the second case,the patient presented with obstructive jaundice due to a biliary stricture.Subsequent imaging revealed sigmoid thickening,which was confirmed to be a metastatic deposit.Distal colonic and anorectal metastases from pancreatobiliary cancers are rare and can masquerade as primary colorectal tumours.The key to the diagnosis is the specific immunohistochemical profile of the intestinal lesion biopsies. | Farshid Ejtehadi Nikolaos A Chatzizacharias Rebecca J Brais Nigel R Hall Edmund M Godfrey Emmanuel Huguet Raaj K Praseedom Asif Jah | 2014 | World Journal of Gastroenterology2014，20，13： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员