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		题名	作者	年代	出处	被引量
	1	Early chronic obstructive pulmonary disease: Beyond spirometry显示文摘The significant healthcare burden associated with chronic obstructive pulmonary disease(COPD) is driving us to improve our understanding of the natural history of this disease. Historically, the focus has been largely centred on diagnosing and treating individuals with moderate and severe disease. However, it is now recognised that the speed of decline in lung function as measured by forced expiratory volume in 1 s occurs faster in the earlier stages of the disease process. As a result, a clearer understanding of the potential benefits of treatment in early COPD is needed. It is recognised that many patients with COPD remain undiagnosed in the community which has prompted global case-finding initiatives. In this review we discuss the difficulties in diagnosing COPD in its early stages, examine the roleof case-finding and look at the evidence for early intervention with therapeutic agents. There is a growing interest in the phenotypic variation amongst patients with COPD and we explore the role of phenotyping in early COPD and its potential benefits in providing a more individualised approach to COPD management. The majority of patients with COPD are known to die from non-respiratory causes such as cardiovascular disease. The mechanistic link is thought to relate to systemic inflammation, causing us to question whether earlier interventions could have a beneficial impact on the burden of co-morbidities for patients with COPD.	Judith A Brebner Alice M Turner	2013	World Journal of Respirology2013，3，3：	5
	2	Boundary layer measurements at low speed on two wings of 45o and 55o sweep显示文摘	Brebner G G Wyatt L A	1961	Ministry of Aviation Aeronautical Research Council Current Papers1961，554，：	1
	3	Structural Properties of InAs Nanocrystals Formed by Sequential Implantation of In and As ions in Si(100)Matrix显示文摘	Tchebotareva A Brebner J L Roorda S	2002	J Appl Phys2002，92，8：	1
	4	When and how to assessfast-changing technologies:a comparative study of medical appli-cations of four generic technologies显示文摘	Mowatt G Bower D J Brebner J A	1997	Health Technol Assess1997，1，14：	1
	5	A patient with aninborn error of vitamin B12 metabolism (cblF) detected bynewborn screening 显示文摘	Armour CM Brebner A Watkins D	2013	Pediatrics2013，132，1：	1
	6	Properties of InAs nanocrystals in silicon formed by sequential ion implantation显示文摘	Tchebotareva A L Brebner J L Roorda S	2001	Nucl Instrum Methods2001，，：	1
	7	A phage vector for the expression of foreig proteins 显示文摘	Maruyama IN Maruyama HI Brebner S A	1994	Proc Natl Acad Sci1994，91，82：	1

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