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| 1 | Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis?显示文摘Beside many efforts to improve outcome, sepsis is still one of the most frequent causes of death in critically ill patients. It is the most common condition with high mortality in intensive care units. The complexity of the septic syndrome comprises immunological aspects- i.e.,sepsis induced immunosuppression- but is not restricted to this fact in modern concepts. So far, exact mechanisms and variables determining outcome and mortality stay unclear. Since there is no typical risk profile, early diagnosis and risk stratification remain difficult, which hinders rapid and effective treatment initiation. Due to the heterogeneous nature of sepsis, potential therapy options should be adapted to the individual. Biomarkers like C-reactive protein and procalcitonin are routinely used as complementary tools in clinical decision-making. Beyond the acute phase proteins, a wide bunch of promising substances and non-laboratory tools with potential diagnostic and prognostic value is under intensive investigation. So far, clinical decision just based on biomarker assessment is not yet feasible. However, biomarkers should be considered as a complementary approach. | Dubravka Kojic Benedikt H Siegler Florian Uhle Christoph Lichtenstern Peter P Nawroth Markus A Weigand Stefan Hofer Thorsten Brenner | 2015 | World Journal of Experimental Medicine2015，5，2： | 14 |
| 2 | Serum levels of d- norgestrel, luteinizing hormone, follicle- stimulating hor- mone, estradiol and progesterone in women during and follow- ing ingestion of combination oral contraceptives containing DL- norgestrel显示文摘 | Brenner P F Mishell D R Jr Stanczyk F Z | 1977 | American Journal of Obstetrics and Gynecology1977，129，2： | 1 |
| 3 | DNA Commission of the ISFG (International Society of Forensic Genetics):recommendations on forensic analysis using Y-chromosome STRs显示文摘 | Gill P Brenner C Brinkmann B | 2001 | Int J Legal Med2001，114，6： | 1 |
| 4 | HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway 显示文摘 | Finzer P Krueger A Stohr M Brenner D Soto U Kuntzen C Krammer PH Rosl F | 2004 | Oncogene2004，23，28： | 1 |
| 5 | DNA commission of the International Society of Forensic Genetics:Recommendations on the interpretation of mixtures显示文摘 | Gill P Brenner C H Buckleton J S | | 0，，： | 1 |
| 6 | CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients显示文摘 | Savoldo Barbara Ramos Carlos Almeida Liu Enli Mims Martha P Keating Michael J Carrum George Kamble Rammurti T Bollard Catherine M Gee Adrian P Mei Zhuyong Liu Hao Grilley Bambi Rooney Cliona M Heslop Helen E Brenner Malcolm K Dotti Gianpie | 2011 | Journal of Clinical Investigation2011，，5： | 1 |
| 7 | MRI -based measurment of hippocampal volume in patientswith combat -related posttraumatic stress disorder显示文摘 | Brenner J Randall P Scott TM | 1995 | Am J psychiatby1995，152，： | 1 |
| 8 | Morbidity and mortality of disease paticnts on dialysis in a 10-years program:Value of combined treatment显示文摘 | Hortal P | 1989 | Med Clin Barc1989，14，92： | 1 |
| 9 | Plasma vitamin D levelsand risk of metabolic syndrome in Canadians显示文摘 | Brenner DR Arora P Garcia-Bailo B | 2011 | Clin InvestMed2011，34，6： | 1 |
| 10 | The effects of the 1990 Manjil earthquake on Sefid Rud buttress dam显示文摘 | INDERMAUR W BRENNER R P ARASTEH T | 1991 | Dam Engineering1991，2，4： | 1 |
| 11 | Experimental Characterization of Eleetrospinning: The Electrically Forced Jet and Instabilities显示文摘 | SHIN Y M HOHMAN M M BRENNER M P | 2001 | Polymer2001，42，： | 1 |
| 12 | Acoustic emssion sensor properties of active fiber composite elements compared with commercial acoustic emission sensors 显示文摘 | Barbezat M Brenner A J Flueler P | 2004 | Sensor and Actuators A2004，，114： | 1 |
| 13 | Controlling the fiber 4iameter during eleclrospinning显示文摘 | S V Fridrikh J H Yu M P Brenner | | Physical Review Letters0，90，11： | 1 |
| 14 | Experimentalcharacterization of electrospinning: The electrically forcedjet and instabilities 显示文摘 | Shin Y M Hohman M M Brenner M P | 2001 | Polymer2001，42，25： | 1 |
| 15 | DNA Commission of the International Society of Forensic Genetics:recommendations on forensic analysis using Y-chromosome STRs显示文摘 | Gill P Brenner C Brinkmann B | 2001 | Forensic Sci Int2001，124，1： | 1 |
| 16 | The adenine nueleotide transloease: Aeentral component of the mitoehondrial permeability transition pore and key player in cell death显示文摘 | Halestrap A P Brenner C | 2003 | Current Medicinal Chemistry2003，10，16： | 1 |
| 17 | Self-assembly of spherical particles on an evaporating sessile droplet 显示文摘 | Schnall-Levin M Lauga E Brenner M P | 2006 | Langmuir2006，22，： | 1 |
| 18 | Repair of complete acromioclavicular dislocation (Tossy stage Ⅲ ) using Balser's hook plate combined with ligament sutures显示文摘 | Mlasowsky B Brenner P Duben W | 1988 | Injury1988，19，： | 1 |
| 19 | Caudal anaesthesia under sedation: a prospective analysis of 512 infants and children 显示文摘 | Brenner L Kettner SC Marhofer P | 2010 | Brl Anaesth2010，104，6： | 1 |
| 20 | DNA commission of the ISFH:recommendations on forensic analysis using ychromosome STRs显示文摘 | Gill P Brenner C Brinkmann B | | 0，，06： | 1 |
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