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| 1 | Neuroimaging the brain-gut axis in patients with irritable bowel syndrome显示文摘AIM:To summarize and synthesize current literature on neuroimaging the brain-gut axis in patients with irritable bowel syndrome(IBS).METHODS:A database search for relevant literature was conducted using Pub Med,Scopus and Embase in February 2015.Date filters were applied from the year2009 and onward,and studies were limited to those written in the English language and those performed upon human subjects.The initial search yielded 797articles,out of which 38 were pulled for full text review and 27 were included for study analysis.Investigations were reviewed to determine study design,methodology and results,and data points were placed in tabular format to facilitate analysis of study findings across disparate investigations.RESULTS:Analysis of study data resulted in the abstraction of four key themes:Neurohormonal differences,anatomic measurements of brain structure and connectivity,differences in functional responsiveness of the brain during rectal distention,and confounding/correlating patient factors.Studies in this review noted alterations of glutamate in the left hippocampus(HIPP),commonalities across IBS subjects in terms of brain oscillation patterns,cortical thickness/gray matter volume differences,and neuroanatomical regions withincreased activation in patients with IBS:Anterio cingulate cortex,mid cingulate cortex,amygdala anterior insula,posterior insula and prefrontal cortex.A striking finding among interventions was the substantia influence that patient variables(e.g.,sex,psychologica and disease related factors)had upon the identification of neuroanatomical differences in structure and con nectivity.CONCLUSION:The field of neuroimaging can provide insight into underlying physiological differences that distinguish patients with IBS from a healthy population. | Kristen R Weaver Lee Anne B Sherwin Brian Walitt Gail D'Eramo Melkus Wendy A Henderson | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 8 |
| 2 | Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial显示文摘 | Stephen B Hanauer Brian G Feagan Gary R Lichtenstein Lloyd F Mayer S Schreiber Jean Frederic Colombel Daniel Rachmilewitz Douglas C Wolf Allan Olson Weihang Bao Paul Rutgeerts | 2002 | The Lancet2002，，9317： | 6 |
| 3 | Early infant male circumcision:Systematic review,risk-benefit analysis,and progress in policy显示文摘AIM To determine whether recent evidence-based United States polices on male circumcision(MC) apply to comparable Anglophone countries,Australia and New Zealand.METHODS Articles in 2005 through 2015 were retrieved from PubM ed using the keyword 'circumcision' together with 36 relevant subtopics.A further PubM ed search was performed for articles published in 2016.Searches of the EMBASE and Cochrane databases did not yield additional citable articles.Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further.The most relevant andrepresentative of the topic were included.Bibliographies were examined to retrieve further key references.Randomized controlled trials,recent high quality systematic reviews or meta-analyses(level 1++ or 1+ evidence) were prioritized for inclusion.A risk-benefit analysis of articles rated for quality was performed.For efficiency and reliability,recent randomized controlled trials,metaanalyses,high quality systematic reviews and large welldesigned studies were used if available.Internet searches were conducted for other relevant information,including policies and Australian data on claims under Medicare for MC.RESULTS Evidence-based policy statements by the American Academy of Pediatrics(AAP) and the Centers for Disease Control and Prevention(CDC) support infant and later age male circumcision(MC) as a desirable public health measure.Our systematic review of relevant literature over the past decade yielded 140 journal articles that met our inclusion criteria.Together,these showed that early infant MC confers immediate and lifelong benefits by protecting against urinary tract infections having potential adverse long-term renal effects,phimosis that causes difficult and painful erections and 'ballooning' during urination,inflammatory skin conditions,inferior penile hygiene,candidiasis,various sexually transmissible infections in both sexes,genital ulcers,and penile,prostate and cervical cancer.Our risk-benefit analysis showed that benefits exceeded procedural risks,which are predominantly minor,by up to 200 to 1.We estimated that more than 1 in 2 uncircumcised males will experience an adverse foreskin-related medical condition over their lifetime.Wide-ranging evidence from surveys,physiological measurements,and the anatomical location of penile sensory receptors responsible for sexual sensation strongly and consistently suggested that MC has no detrimental effect on sexual function,sensitivity or pleasure.United States studies showed that early infant MC is cost saving.The evidence supporting early infant MC has further strengthened since the positive AAP and CDC reviews.CONCLUSION Affirmative MC policies are needed in Australia and New Zealand.Routine provision of accurate,unbiased education,and access in public hospitals,will maximize health and financial benefits. | Brian J Morris Sean E Kennedy Alex D Wodak Adrian Mindel David Golovsky Leslie Schrieber Eugenie R Lumbers David J Handelsman John B Ziegler | 2017 | World Journal of Clinical Pediatrics2017，6，1： | 2 |
| 4 | Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury显示文摘 | Caudrillier Axelle Kessenbrock Kai Gilliss Brian M Nguyen John X Marques Marisa B Monestier Marc Toy Pearl Werb Zena Looney Mark R | 2012 | EN2012，，7： | 2 |
| 5 | Microbial populations responsible for specific soil suppressiveness to plant pathogens显示文摘 | David M W Jos M R Brian B M | 2002 | Phytopathol2002，，40： | 1 |
| 6 | Simultaneous inversion of pre-stack seismic data 显示文摘 | Hampson D P Brian H R Brad P B | 2005 | Expanded Abstracts of 75th Annual Internat SEG Mtg2005，，： | 1 |
| 7 | Modelling an infrared man portable air defence system显示文摘 | Birchenall R P Richardson M A Brian B | 2010 | Infrared Physics & Technology2010，53，5： | 1 |
| 8 | Substrate-assisted catalysis in sialic acid aldolase 显示文摘 | Brian J S Michael C L Joao A R G B | 1999 | J Org Chem1999，64，： | 1 |
| 9 | Design and Testing of Thermally Stable Filter Using Bimetal Compensation 显示文摘 | Keats Brian F Mansour Raafat R Gorbet Robert B | 2007 | IEEE MTT-S Int Microwave Symp2007，，3： | 1 |
| 10 | Application of digital image analysis and flow cytometry to enumerate marine viruses stained with SYBR Gold显示文摘 | Chen F Lu J R Brian J B | 2001 | Appl Environ Mierobiol2001，67，2： | 1 |
| 11 | An assessment of toxicity in profundal lake sediment due to deposition of heavy met- als and persistent organic pollutants fi;om the atmosphere显示文摘 | Rippey B Rose N Brian R | 2008 | Environment International2008，34，3： | 1 |
| 12 | The processing of metal matrix composites-an overview显示文摘 | BRIAN R YUEN H C LEE W B | 1997 | Journal of Materials Processing Technology1997，63，13： | 1 |
| 13 | Light gap disturbance,recruitment limitation,and tree diversity in a neotropical forest显示文摘 | Hubbell S P Foster R B O'Brian S T Harms K E Condit R Wechsler B Wright S J Loo de Lao S | | 0，，： | 1 |
| 14 | Optical Properties of Tm^3+ Ions in Alkali Germanate Glass显示文摘 | Brian M W Norman P B Donald J R | 2006 | Journal of Non-Crystalline Solids2006，352，： | 1 |
| 15 | Imaging internal multiples from subsalt VSP data-Examples of target-oriented interferometry显示文摘 | Vasconcelos I Snieder R Brian Hornby B | 2008 | Geophysics2008，73，4： | 1 |
| 16 | The control of rotting and browning of litchi fruit by hot benomyl and plastic film 显示文摘 | Kevin J S Brian I B Grantley R C | 1982 | Scientia Horticalture1982，16，3： | 1 |
| 17 | An Electronic,Aptamerbased small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids 显示文摘 | Brian R B Rebecca Y L McCall S W | 2006 | J Am Chem Soc2006，，128： | 1 |
| 18 | Simultaneous single event charge sharing and parasitic bipolar conduction in a highly-scaled sram design 显示文摘 | BRIAN D O DENNIS R B KEVIN M W | 2005 | IEEE Trans on Nucl Sci2005，52，6： | 1 |
| 19 | Copper transporter 2 regulates the cellular accu- mulation and cytotoxicity of cisplatin and carboplatin 显示文摘 | BRIAN G B R CHRISTOPHERA L A ROOHANGIZ S | 2009 | Clin Cancer Res2009，15，13： | 1 |
| 20 | Airline Fleet Assignment with time window显示文摘 | Brian R Cynthia B Tim K | | 0，，01： | 1 |
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