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| 1 | 血管性认知障碍的诊断标准:国际血管性行为与认知障碍学会的申明显示文摘长期以来,脑血管病(CVD)就被认为是认知损害的一个重要原因,但是有关脑血管病后认知障碍的概念化却有着一段多变的历史。'动脉变硬'或脑的动脉粥样硬化是'老化'的原因,是存在已久的观点,在20世纪60年代受到了来自英格兰纽卡斯尔的神经病理学研究的质疑。这些研究表明,血管性痴呆(vascular dementia,Va D)与超过一定程度的多发性脑梗死有关。 | 徐岩 郭起浩 Sachdev P Kalaria R O'Brien J Skoog I Alladi S Black SE Blacker D Blazer DG Chen C Chui H Ganguli M Jellinger K Jeste DV Pasquier F Paulsen J Prins N Rockwood K Roman G Scheltens P | 2014 | 神经病学与神经康复学杂志2014，11，3： | 19 |
| 2 | Skeletal muscle mitochondrial health and spinal cord injury显示文摘Mitochondria are the main source of cellular energy production and are dynamic organelles that undergo biogenesis, remodeling, and degradation. Mitochondrial dysfunction is observed in a number of disease states including acute and chronic central or peripheral nervous system injury by traumatic brain injury, spinal cord injury(SCI), and neurodegenerative disease as well as in metabolic disturbances such as insulin resistance, type Ⅱ diabetes and obesity. Mitochondrial dysfunction is most commonly observed in high energy requiring tissues like the brain and skeletal muscle. In persons with chronic SCI, changes to skeletal muscle may include remarkable atrophy and conversion of muscle fiber type from oxidative to fast glycolytic, combined with increased infiltration of intramuscular adipose tissue. These changes contribute to a proinflammatory environment, glucose intolerance and insulin resistance. The loss of metabolically active muscle combined with inactivity predisposes individuals with SCI to type Ⅱ diabetes and obesity. The contribution of skeletal muscle mitochondrial density and electron transport chain activity to the development of the aforementioned comorbidities following SCI is unclear. A better understanding of the mechanisms involved in skeletal muscle mitochondrial dynamics is imperative to designing and testing effective treatments for this growing population. The current editorial will review ways to study mitochondrial function and the importance of improving skeletal muscle mitochondrial health in clinical populations with a special focus on chronic SCI. | Laura C O'Brien Ashraf S Gorgey | 2016 | World Journal of Orthopedics2016，7，10： | 3 |
| 3 | 外加应力对贝氏体相变组织形貌的影响显示文摘为揭示贝氏体相变机制及外加应力对它的影响,采用透射电镜研究了140MPa的外加拉应力对中碳低合金钢35MV7的450°C等温贝氏体相变组织形貌的影响.研究发现,由于外加应力的存在,贝氏体相变基元及其组成的铁素体条的尺寸变得非常粗大并形成多样的变态.这种尺寸的变化是由于外加应力产生额外的相变驱动力,使相变基元块可以克服更大的弹性应变能而长成更大的体积. | 苏铁健 李树奎 张朝晖 AEBY-GAUTIER E DENIS S BRIEN V | 2005 | 材料科学与工艺2005，13，3： | 3 |
| 4 | Two-component phase-average turb ulence st atistics downstream of a rotating spoked-wheel wake generator显示文摘 | O'Brien J E Capp S P | 1989 | Journal o f Turbomachinery1989，111，10： | 2 |
| 5 | Use of polymerase chain reaction for rapid detection of gene insertions in whole yeast cells显示文摘 | Sathe G M OBrien S Mclaughlin M M | 1991 | Nucleic Acids Res1991，19，： | 2 |
| 6 | An introduction to wavelet analysis in oceanography and meteorology: with application to the dispersion of Yannai waves显示文摘 | Meyers S D Kelly B G O'Brien J J | 1993 | Mon Wea Rev1993，121，10： | 2 |
| 7 | Regulation of the hypoxiainducible transcription factor 1 alpha by the ubiquitin - proteasome pathway显示文摘 | Kallio PJ Wilson WJ O' Brien S | 1999 | J Biol Chem1999，274，： | 1 |
| 8 | The angiogenic factor midkine is expressed in bladder cancer, and overexpression correlates with a poor outcome in patients with invasive cancers 显示文摘 | Cranston D Fuggle S | 1996 | Cancer Res1996，56，11： | 1 |
| 9 | Analysis of variation in isolates of Rhizoctonia solani by random amplified polymorohic DNA assay显示文摘 | Duncan S Barton J E O'brien P A | 1993 | Mycol Res1993，15，： | 1 |
| 10 | An evidence-based review of important issues concerning neonatal hyperbilirubinemia显示文摘 | Ip S Chung M Kulig J O'Brien Sege R Glicken S | 2004 | Pediatrics2004，114，1： | 1 |
| 11 | Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase显示文摘 | Kantarjian HM Cortes J O'Brien S | 2002 | Blood2002，99，10： | 1 |
| 12 | A surface plasmon resonance array biosensor based on spectroscopic imaging显示文摘 | Michael J O Brien I I Victor H Perez-Luna Brueck S R J | 2001 | Biosensors Bioelectronics2001，16，： | 1 |
| 13 | 3% follow-up of 1 022 valve replacement显示文摘 | O'Brien MF Harrocks S Stafford EG The homograft aortic valve:A 29-year 99 | 2001 | J Heart Valve Dis2001，10，3： | 1 |
| 14 | Analysis of variation in isolates of Rhizoctonia solani by random amplified polymorphic DNA assay显示文摘 | Duncan S Barton J E O′Brien P A | 1993 | Mycol Res1993，97，9： | 1 |
| 15 | Molecular phylogeny of the red panda (Ailurus fulgens)显示文摘 | Slattery J P O'Brien S J | 1995 | J Hered1995，86，6： | 1 |
| 16 | The vascular tissue of the lodicules of wheat显示文摘 | ZEE S Y O'BRIEN T P | 1971 | Austral J Biol Sci1971，4，： | 1 |
| 17 | C60:Buckminster- fullerene显示文摘 | Kroto H W Heath J R O'Brien S C | 1985 | Nature1985，318，： | 1 |
| 18 | A human colon cancer cell capable of initiating tumour growth in immunodefieient mice 显示文摘 | O'Brien CA Pollett A Gallinger S | 2007 | Nature2007，445，7123： | 1 |
| 19 | Chronic myelogenons leuke- mia显示文摘 | O'Brien S Abboud CN Akhtari M | 2012 | J Natl Compr Canc Netw2012，10，1： | 1 |
| 20 | Interannual variability in the eastern subtropical North Pacific Ocean显示文摘 | Leonardi A P Morey S L O'Brien J J | | 0，，： | 1 |
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