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| 1 | 血管性认知障碍的诊断标准:国际血管性行为与认知障碍学会的申明显示文摘长期以来,脑血管病(CVD)就被认为是认知损害的一个重要原因,但是有关脑血管病后认知障碍的概念化却有着一段多变的历史。'动脉变硬'或脑的动脉粥样硬化是'老化'的原因,是存在已久的观点,在20世纪60年代受到了来自英格兰纽卡斯尔的神经病理学研究的质疑。这些研究表明,血管性痴呆(vascular dementia,Va D)与超过一定程度的多发性脑梗死有关。 | 徐岩 郭起浩 Sachdev P Kalaria R O'Brien J Skoog I Alladi S Black SE Blacker D Blazer DG Chen C Chui H Ganguli M Jellinger K Jeste DV Pasquier F Paulsen J Prins N Rockwood K Roman G Scheltens P | 2014 | 神经病学与神经康复学杂志2014，11，3： | 19 |
| 2 | Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts显示文摘The accumulation and aggregation of alpha-synuclein(α-syn)in several tissue including the brain is a major pathological hallmark in Parkinson’s disease(PD).In this study,we show that α-syn can be taken up by primary human cortical neurons,astrocytes and skin-derived fibroblasts in vitro.Our findings that brain and peripheral cells exposed to α-syn can lead to impaired mitochondrial function,leading to cellular degeneration and cell death,provides additional evidence for the involvement of mitochondrial dysfunction as a mechanism of toxicity of α-syn in human cells. | Nady Braidy Wei-Ping Gai Ying Hua Xu Perminder Sachdev Gilles J Guillemin Xing-Mai Jiang J William O Ballard Martin P Horan Zhi Ming Fang Beng H Chong Daniel Kam Yin Chan | 2013 | Translational Neurodegeneration2013，2，1： | 4 |
| 3 | A computer-based substation switching scheme,WESCANEX 95显示文摘 | Dhakal P Sachdev M S | 1995 | Communications Power and Computing Conference Proceedings IEEE1995，1，1： | 1 |
| 4 | Zinc deficiency in pregnancy and fetal outcome 显示文摘 | SHAH D SACHDEV H P S | 2006 | Nutrition Reviews2006，64，1： | 1 |
| 5 | Early dectecti0n of diabetic perpher- al neuropathy with corneal confocal microscopy显示文摘 | Hossain P Sachdev A Malik RA | 2005 | Lancet2005，366，9494： | 1 |
| 6 | High(15 Hz)and low(1 Hz) frequency transcranial magnetic stimulation have different acute ef- fects on regional cerebral blood flow in depressed patients显示文摘 | Loo C K Sachdev P S Haindl W | 2003 | Psy chol Med2003，33，99： | 1 |
| 7 | Homocyteine,cerebrovascular disease and brain atrophy显示文摘 | Sachdev P | 2004 | J Neurol Sci2004，226，12： | 1 |
| 8 | White matter hyperintensities in mid-adult life显示文摘 | Sachdev P Chen X Wen W | 2008 | Curt Opin Psychiatry2008，21，3： | 1 |
| 9 | Development of Electrorefiner Waste Salt Disposal Process for the EBR-Ⅱ Spent Fuel Treatment Project显示文摘 | Simpson M F Sachdev P | 2008 | Nucl Eng Technol2008，40，3： | 1 |
| 10 | Differential expression of MUC genes in endometrial and cervical' tissues and tumors 显示文摘 | Hebbar V Damera G Sachdev G P | 2005 | BMC Cancer2005，5，： | 1 |
| 11 | Frequency and clinical, neuropsychological and neuroimaging correlates of apathy following stroke-the Sydney Stroke Study显示文摘 | Brodaty H Sachdev P S Withall A | 2005 | Psychol Med2005，35，12： | 1 |
| 12 | The topography of white matter hyperintensities on brain MRI in healthy 60 to 64 year old individuals显示文摘 | Wen W Sachdev P | 2004 | NeuroIm-ge2004，22，1： | 1 |
| 13 | Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia显示文摘 | Roman GC Sachdev P Royall DR | 2004 | Neurol Sci2004，22，6： | 1 |
| 14 | Right ventricular strain for prediction of surviv- al in patients with pulmonary arterial hypertension 显示文摘 | SACHDEV A VILLARRAGA H R FRANTZ R P | 2011 | Chest2011，189，： | 1 |
| 15 | Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology,and induces cell transformatlon显示文摘 | Zeng LY Sachdev P Yan L | 2000 | Mol Cell Biol2000，20，24： | 1 |
| 16 | Homocysteine,cerebrovascular disease and brain atrophy显示文摘 | Sachdev P | 2004 | J Neurol Sci2004，226，12： | 1 |
| 17 | Structural brain networks and nem'opsy- chiatric disorders 显示文摘 | Wen W He Y Sachdev P | 2011 | Curr Opin Psychiatry2011，24，3： | 1 |
| 18 | Diagnostic crite- ria for vascular cognitive disorders: a VASCOG statement 显示文摘 | Sachdev P Kalaria R O'Brien J | 2014 | Alzheimer Dis Assoc Disord2014，28，3： | 1 |
| 19 | The narrative in neurology and psychia- try显示文摘 | Sachdev P | 2011 | Current Opinion in Psychiatry2011，24，3： | 1 |
| 20 | Vascular cognitive disorder : A new diagnostic category updating vascular cognitive impairment and vascular dementia显示文摘 | Roman GC Sachdev P Royall DR | 2007 | Neurological Sciences2007，226，12： | 1 |
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