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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Bacteriocin production by Lactobacillus pentosus B96 can be expressed as a function of temperature and NaC1 concentration显示文摘 | DELGADO A BRITO D PERES C | 2005 | Food Microbiology2005，22，6： | 1 |
| 3 | Descriptive study on pulmonary embolism in an urban-teaching hospital 显示文摘 | SCHWED D MURALI G BRITO C | 2006 | Chest2006，130，： | 1 |
| 4 | Ultrasonic Doppler Velocimetry in Liquid Gallium 显示文摘 | Brito D Natal H C Cardin P | 2001 | Experiments in Fluids2001，31，6： | 1 |
| 5 | Community genomics among stratified microbial assemblages in the ocean's interior显示文摘 | DeLong E F Preston C M Mincer T Rich V Hallam S J Frigaard N U Martinez A Sullivan M B Edwards R Brito B R Chisholm S W Karl D M | | 0，，5760： | 1 |
| 6 | Effects of environmental factors, age and genotype on sperm production and semen quality in Bos indicus and Bos taurus AI bulls in Brazil显示文摘 | Brito L F C Silva A E D F Rodrigues L H | 2002 | Anita Reprod Sci2002，70，： | 1 |
| 7 | Transfer RNA -mediated antitermination in vitro 显示文摘 | Putzer H Condon C Brechemier - Baey D Brito R Grunberg - Manago M | 2002 | Nucleic Acids Research2002，30，14： | 1 |
| 8 | Transfer RNA-mediated antitermination in vitro显示文摘 | Putzer H Condon C Breehemier-Baey D Brito R Grunberg Manago M | 2002 | Nucleic Acids Research2002，30，14： | 1 |
| 9 | Bacteriocin production by Lactobacilllus pentosus B96 can be expressed as a function of temperature and NaC1 concentration显示文摘 | Delgado A Brito D Peres C | 2005 | Food Microbiolgy2005，22，6： | 1 |
| 10 | The origin and evolution of the South American Platform显示文摘 | Almeida F F M Brito Neves B B Carneiro C D R | | 0，，： | 1 |
| 11 | Risk assessment for redevelopment of contaminated land at an old industrial site显示文摘 | Vendas D F Costa C N Brito M G | 2008 | WSEAS Transactions on Environment and Development2008，2，4： | 1 |
| 12 | A bacterial sensor of plant cell contact controls the transcriptional induction of Ralstonia solanacearum pathogenicity genes 显示文摘 | B Brito C Boucher | 2000 | EMBO J2000，19，10： | 1 |
| 13 | Technical option on tetralogy of Fallot with abnormal coronary artery:cases report显示文摘 | Assump(c)(a)o CR Brito Jde D Pfeifer E | | 0，，02： | 1 |
| 14 | Temperate forages ensiled with molasses or fresh cheese whey: Effects on conser- vation quality, effluent losses and ruminal degradation显示文摘 | Cajarville C Britos A Garciarena D | 2012 | Animal Feed Science And Technology2012，171，1： | 1 |
| 15 | Occurrence of bloodstream infection with different types of central vascular catheter in critically neonates显示文摘 | de Brito C S de Brito D V Abdallah V O | 2010 | J Infect2010，60，2： | 1 |
| 16 | Low risk papillary thyroid can- cer显示文摘 | Brito J P Hay I D Morris J C | 2014 | BMJ2014，348，16： | 1 |
| 17 | Ultrasonic Doppler Velocimetry in Liquid Gallium 显示文摘 | Brito D Nataf H C Cardin P | 2001 | Experiments in Fluids2001，31，6： | 1 |
| 18 | Ultrasonic Doppler velocimetry in liquid gallium 显示文摘 | Brito D Natal H C Cardin P | 2001 | Experiments in Fluids2001，31，6： | 1 |
| 19 | Low risk papillary thyroid cancer 显示文摘 | Brito J P Hay I D Morris J C | 2014 | British Medical Journal2014，348，3045： | 1 |
| 20 | Temperate forages ensiled with molasses or fresh cheese whey: Effects on conservation quality, effluent losses and ru- minal degradation显示文摘 | Cajarville C Britos A Garciarena D | 2012 | Animal Feed Science and Technology2012，171，1： | 1 |
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