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28篇 您的检索式:作者名="Browd"
    题名 作者 年代 出处 被引量
1术中神经电生理监测在单椎板入路选择性神经后根离断术中的作用显示文摘目的单椎板入路选择性神经后根离断术(SL-SDR)治疗痉挛性脑瘫完全依赖术中神经电生理监测结果。本研究旨在讨论SL-SDR术中肌电图判读对神经根选择和离断的影响及作用。方法回顾分析2016年5月至2019年3月在上海交通大学附属儿童医院神经外科采用改良神经电生理监测离断方案指导下SL-SDR治疗的痉挛性脑瘫患儿的临床资料,重点关注术中肌电图判读及其与术前临床表现的相关性,以及比较采用不同神经电生理监测离断方案解读术中肌电图时的神经后根选择差异。结果共纳入318例患儿,男性231例、女性87例,平均年龄5.9岁,32例为偏瘫、161例为双侧瘫、125例为四肢瘫。每例患儿有2~8组目标肌群(术前肌张力≥2级)。术中神经电生理监测结果显示,探测的21728枚神经小根[(68.3±8.2)枚/例]中6272枚(28.9%)与肛门括约肌相关,15456枚[(48.6±7.6)枚/例]与下肢肌群相关,其中,神经后根11009枚[(34.6±7.4)枚/例]。共有3370枚[(10.6±4.7)枚/例]符合改良神经后根离断方案,其中3061枚50%部分离断、309枚75%部分离断。术前粗大运动功能分级(GMFCS)分级Ⅰ~Ⅴ级的离断率(部分离断的神经后根数/下肢肌群相关神经后根数)分别为15.8%、22.3%、33.4%、41.8%和45.7%。75%部分离断的离断率随术前GMFCS分级的递增而增加,分别为1.5%、4.8%、8.5%、14.1%和15.2%。术后3周,2068组目标肌群肌张力显著降低[(1.7±0.5)级对(2.7±0.6)级]。术前GMFCS分级Ⅰ和Ⅱ级患儿采用传统离断方案约有20%的病例无法识别任何1枚约20%需离断的神经后根,而随着患儿术前GMFCS分级的递增,传统与改良方案离断的符合率逐步提高,分别为39.5%、41.3%、52.2%、54.1%和62.8%。结论由于SL-SDR完全依赖于术中肌电图判读,使得术中神经电生理监测显得至关重要。改良神经电生理监测离断方案指导下的SL-SDR可以安全、有效治疗痉挛性脑瘫。SL-SDR术中肌电图及其与临床表现相关的预后,可以使临床医师更好地理解此类患儿脊髓神经元环路的运作模式。Xiao B Constatntini S Browd SR Zhan Q Jiang W Mei R 詹琪佳(编译) 2020中国现代神经疾病杂志2020,20,4:4
2Surgical shunt infection:significant reduction when using intraventricular and systemic antibiotic agents 显示文摘Ragel BT Browd SR Schmidt RH 2006J Neurosurg2006,105,2:1
3Prophylaxis for deep VCllOUS thrombosis in nenosurgery: a review of the litera- ture显示文摘Browd SR Ragel BT Davis GE 2004Nenrosurgical Focus2004,17,4:1
4New and improved ways to treat hydrocephalus: pursuit of a smart shunt 显示文摘Lutz BR Venkataraman P Browd SR 2013Surg Neurol Int2013,4,:1
5N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma 显示文摘Browd SR Kenney AM Gottfried ON 2006Cancer Res2006,66,5:1
6Failure of cerebro-spinal fluid shunts: part I: obstruction and mechanicalfailare 显示文摘Browd SR Ragel BT Gottfried ON 2006Pediatr Neurol2006,34,2:1
7Surgical shunt infection: significant reduction when using intraventricular and systemic antibiotic agents显示文摘Ragel BT Browd SR Schmidt RH 2006J Neurosurg2006,105,2:1
8MULTIDRUG-RESISTANT ENTEROCOCCUS FAECIUM MENINGITIS IN A TODDLER: CHARACTERIZATION OF THE ORGANISM AND SUCCESSFUL TREATMENT WITH INTRAVENTRICULAR DAPTOMYCIN AND INTRAVENOUS TIGECYCLINE显示文摘Heather B. Jaspan Adam W. Brothers Angela J. P. Campbell John K. McGuire Samuel R. Browd Thomas J. Manley Daniel Pak Scott J. Weissman 2010The Pediatric Infectious Disease Journal2010,,4:1
9Failure of cerebrospinal fluid shunts part I:obstruction and mechanical failure显示文摘Browd SIR Ragel BT Gotffried ON 2006Pediatric Neurosur- gery2006,34,2:1
10Surgical shunt infec- tion: significant reduction when using intraventricular and systemic antibiotic agents 显示文摘Ragel BT Browd SR Schmidt RH 2006J Neurosurg2006,105,2:1
11Surgical shunt infection: significant reduction when using intraventricular and systemic antibiotic agents 显示文摘Ragel BT Browd SR Schmidt RH 2006J Neurosurg2006,105,:1
12Surgical shunt infection:significant reduction when using intraventricular and systemicantibiotic agents显示文摘Ragel BT Browd SR Schm idt RH 2006J Neurosurg2006,105,2:1
13Morphomelric and qualitative analysis of congenital occipitocervical instahilily in children: implications for patients with Down syndrome 显示文摘Browd S Healy LJ Dohie C 2006J Neurosurg2006,105,1:1
14Response of Het erodera glycines populations to a postemergence herbicide mixture and simulated insect defoliation 显示文摘Browde J A Tylka G L Pedigo L P 1994Journal of Nematology1994,26,4:1
15Use of the ETV Success Score to explain the variation in reported endoscopic third ventriculostomy success rates among published case series of childhood hydrocephalus显示文摘Kulkarni AV Riva-Cambrin J Browd SR 2011J Neurosurg Pediatr2011,7,2:1
16A new fiber- mediated carbon dioxide laser facilitates pediatric spinal cord detethering: technical note 显示文摘Browd SR Zauberman J Karandikar M 2009J Neurosurg Pediatr2009,4,3:1
17The treatment of symptomatic vertebral hemangioma by radiotherapy显示文摘 Spiro F Browde S 1986Spine1986,11,:1
18N-myc can substitute for insulinlike growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma显示文摘Browd SR Kenney AM Gottfried ON 2006Cancer Res2006,66,5:1
19Surgical shunt infection:significant reduction when Using intraventricular and systemic antibiotic agents显示文摘Ragel BT Browd SR Schmidt RH 2006J Neurosurg2006,105,2:1
20Surgical shunt infection:significant reduction when using intraventricular and systemic antibiotic agents显示文摘Ragel BT Browd SR Schmidt RH 2006J Neurosurg2006,105,2:1
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