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118篇 您的检索式:作者名="Bruce F M"
    题名 作者 年代 出处 被引量
1Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) 2006英国医学杂志中文版2006,9,5:3
2Analysis of feline calicivirus capsid protein genes:identification of varia ble antigenic determinant regions of the protein显示文摘Bruce S S Julia F R William L M 1993J Gen Virol1993,74,:1
3Factors Affecting the Process of Collaborative Product Development显示文摘D Littler F Leverick M Bruce 1995Journal of Product Innovation Management1995,12,1:1
4Development of broodstock diets for the European sea bass (Dicentrarchus labrax)with special emphasis on the importance of n-3 and n-6 HUFA to reproductive performance 显示文摘Bruce M P Oyen F Bell J G 1999Aquaculture1999,177,:1
5Lithium insertion into manganese spinels 显示文摘Thackeray M M David W I F Bruce P G 1983Mater Res Bull1983,18,4:1
6Factors affecting the process of collaborative product development: A study of U K manufacturers of information and communications technology products显示文摘Litter D Leverick F Bruce M 1995Journal of Product Innovation Management1995,12,1:1
7Lithium insertion into manganese spinels显示文摘Thackeray M M David W I F Bruce P G 1983Materials Research Bulletin1983,18,4:1
8Calcium nephrolithiasis; effect of water hardness on urinary electrolytes 显示文摘Schwartz B F Schenkman N S Bruce J E Leslie S W Stoller M L 2002Urology2002,60,:1
9Traditional fertilizion and its effect on corn insect populations in the Guatemalan highlands显示文摘Helda M Ivette P Bruce F 2001Agriculture Ecosystems & Environment2001,84,:1
10Zinc contamination decreases the bacterial diversity of agricultural soil显示文摘Bruce F M Fiona A N Nnanna C U 2003FEMS Microbiology Ecology2003,43,1:1
11Zinc contamination decreases the bacterial diversity of agricultural soil显示文摘Bruce F M 2003FEMS Microbiology Ecology2003,43,1:1
12Lithium Insertion into Manganese Spinels显示文摘Thackeray M M David W I F Bruce P G 1983Mater Res Bull1983,18,:1
13Total Synthesis of ( + ) -Rocaglamide and Some Aryl Analogues显示文摘DOBLER M R BRUCE I CEDERBAUM F 2001Tetrahedron Lett2001,42,:1
14Development of broodstock diets for the European sea bass (Dicentrarchus labrax) with special emphasis on the importance of n-3 and n-6 highly unsaturated fatty acid to reproductive performance 显示文摘Bruce M Oyen F Bell G 1999Aquaculture1999,177,:1
15Factors affecting the process of collaborative product development 显示文摘D LITTLER F LEVERICK M BRUCE 1995Journal of Product Innovation Management1995,12,1:1
16Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid 显示文摘Beal M F Emmanuel B Bruce G 1993The J Neurosci1993,13,10:1
17Studies of australian soft corals ⅩⅩⅩⅤ: The terpenoid chemistry of soft corals and its implications 显示文摘Coil John C Bowden Bruce F Tapiolas Dianne M 1985Tetrahedron1985,41,6:1
18Heat transfer enhancement in Ferro fluids subjected to steady magnetic fields显示文摘CHITINI T BRUCE A F JOHN M 0,,201:1
19Success of factor collaboration produce development: A study of supplier of information communication technology显示文摘Bruce M L Leverick F Wilson D 1995R & D Management1995,25,1:1
20Zinc contamination decreases the bacterial diversity of agricultural soil显示文摘Bruce F M 2003Ferns Microbiology Ecology2003,43,:1
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