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| 1 | Hepatocytic differentiation of mesenchymal stem cells in cocultures with fetal liver cells显示文摘瞄准:为了与胎儿的肝细胞(FLC ) 和可能性在合作文化调查间充质的干细胞(MSC ) 的 hepatocytic 区别膨胀,区分了 hepatocytic 房间。方法:MSC 被制动火箭与绿荧光灯的蛋白质(GFP ) 标记病毒的基因转导变异。同种细胞的显著 MSC 在用与干细胞补充的fibronectin涂的培养皿和媒介刺激条件的肝下面是也有教养的因素( SCF ), hepatocyte 生长因素( HGF ),表皮的生长因素( EGF ),和成纤维细胞生长因素 4 ( FGF-4 )独自一个,或在刚孤立的 FLC 的存在。在合作文化的房间被收获,并且 GFP+ 或 GFP- 房间用荧光被分开激活的房间排序。为肝 specific 标记 cytokeratin-18 (CK-18 ) 的反向的抄写聚合酶链反应(RT-PCR )( 法新社) ,白朊,和 alpha-fetoprotein 在不同房间人口被执行。结果:在指定文化条件下面,与 FLC co 有教养的老鼠 MSC 超过二个星期表示了白朊, CK-18,和 AFP-RNA。在 wk 3, MSC 失去了 hepatocytic 基因表示,可能由于 cocultured FLC 的增生。FLC 也在合作文化和一个很高的生长潜力显示出稳定的肝 specific 基因表情。结论:从骨髓的老鼠 MSC 能面对 FLC 在试管内区分 hepatocytic 房间,在合作文化的 MSC 的存在也为 FLC 的扩大和区别提供有益的环境。 | Claudia Lange Helge Bruns Dietrich Kluth Axel R Zander Henning C Fiegel | 2006 | World Journal of Gastroenterology2006，12，15： | 23 |
| 2 | Prognostic value of CA 19-9, CEA, CRP, LDH and bilirubin levels in locally advanced and metastatic pancreatic cancer: results from a multicenter, pooled analysis of patients receiving palliative chemotherapy显示文摘 | Michael Haas Volker Heinemann Frank Kullmann Rüdiger P. Laubender Christina Klose Christiane J. Bruns Stefan Holdenrieder Dominik P. Modest Christoph Schulz Stefan Boeck | 2013 | Journal of Cancer Research and Clinical Oncology2013，，4： | 4 |
| 3 | Physical and chemical characteristics of the active layer and permafrost, Herschel Island, western arctic coast, Canada显示文摘 | Kokelj S V Smith C A S Brun C R | 2002 | Permafrost and Periglacial Process2002，13，： | 1 |
| 4 | The World Health Organization (WHO) classification of the myeloid neoplasms显示文摘 | Vardiman J W Harris N L Brunning R D | 2002 | Blood2002，100，7： | 1 |
| 5 | Immunopeptides in the defense reactions of Glossina morsitans to bacterial and Trypanosoma brucei brucei infections显示文摘 | Boulanger N Brun R Ehret-Sabatier L | 2002 | Insect Biochem Mol Biol2002，32，4： | 1 |
| 6 | The World Health Organization (WHO) classification of the myeloid neoplasms 显示文摘 | Vardiman J W Harris N L Brunning R D | 2002 | Blood2002，100，7： | 1 |
| 7 | A Closer Look at Reverberation Chambers-3-D Simulation and Experimental Verification显示文摘 | BRUNS C VAHLDIECK R | | 0，，03： | 1 |
| 8 | Tip position of long term- central venous access devices used for parenteral nutrition 显示文摘 | Dechicco R Seidner DL Brun C | 2007 | JPEN J Parenter Enteral Nutu2007，31，5： | 1 |
| 9 | Feasibility,accuracy and of chorionic vilus sampling:,a report d 10 741 cases显示文摘 | Mangione R Gangbo F | 2003 | Prenat Diagn2003，23，： | 1 |
| 10 | Chemo-radiotherapy with gemcitabine and continuous 5-FU in patients with primary inoperable pancreatic cancer 显示文摘 | Wilkowski R Thoma M Bruns C | 2006 | JOP2006，7，4： | 1 |
| 11 | Brown adipose tissue activitycontrols triglyceride cIearance显示文摘 | Bartelt A Bruns OT Reimer R | 2011 | Nat Med2011，17，2： | 1 |
| 12 | Tip position of long-termcentra] venous access devices used for parenteral nutrition 显示文摘 | DeChicco R Seidner DL’Brun C | 2007 | JPEN J Parenter Enteral Nutr2007，31，5： | 1 |
| 13 | Statistical design- principal component analysis optimization of a multiple response procedure using cloud point extraction and simultaneous determination of metals by ICP OES显示文摘 | BEZERRA M A BRUNS R E FERREIRA S L C | 2009 | Analyfica Chimica Aeta2009，580，2： | 1 |
| 14 | Résultat surla reproduction de Acipenser baerii en 1982显示文摘 | Williot P Brun R | | 0，，287： | 1 |
| 15 | Differential activation of adipogenesis by multiple PPAR isoforms显示文摘 | Brun R P Tontonoz P Forman B M | 1996 | Genes Dev1996，，10： | 1 |
| 16 | Knowledge-based scheduling systems in indusry and medicine显示文摘 | Sauer J Bruns R | 1997 | IEEE Expert Intelligent Systems & Their Application1997，12，1： | 1 |
| 17 | Practical identifiability of ASM2d parameters--systematic selection and tuning of parameter subsets 显示文摘 | Brun R Kfihni M Siegrist H Gujer W Reichert P | 2002 | Water Research2002，36，16： | 1 |
| 18 | Positive Behavioral Interventions and Supports in New Hampshire:Effects of LargeScale Implementation of School-Wide Positive Behavior Support on Students Discipline and Academic Achievement显示文摘 | Muscott S Mann L Le Brun R | 2008 | Journal of Positive Behavior Interventions2008，，3： | 1 |
| 19 | Challenges to organic potato farming disease and nutrient manage- ment显示文摘 | Finckh M R Schulte-Geldermann E Bruns C | 2006 | Potato Research2006，49，： | 1 |
| 20 | Box-Be-hnken design:An alternative for the optimization of ana-lytical methods显示文摘 | Ferreira S L Bruns R E Ferreira H S | 2007 | Analytica Chimica Acta2007，597，2： | 1 |
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