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| 1 | Hepatocellular carcinoma: Advances in diagnosis, management, and long term outcome显示文摘Hepatocellular carcinoma(HCC) remains a common and lethal malignancy worldwide and arises in the setting of a host of diseases. The incidence continues to increase despite multiple vaccines and therapies for viruses such as the hepatitis B and C viruses. In addition, due to the growing incidence of obesity in Western society, there is anticipation that there will be a growing population with HCC due to non-alcoholic fatty liver disease. Due to the growing frequency of this disease, screening is recommended using ultrasound with further imaging using magnetic resonance imaging and multi-detector computed tomography used for further characterization of masses. Great advances have been made to help with the early diagnosis of small lesions leading to potential curative resection or transplantation. Resection and transplantation maybe used in a variety of patients that are carefully selected based on underlying liver disease. Using certain guidelines and clinical acumen patients may have good outcomes with either resection or transplantation however many patients are inoperable at time of presentation. Fortunately, the use of new locoregional therapies has made down staging patients a potential option making them potential surgical candidates. Despite a growing population with HCC, new advances in viral therapies, chemotherapeutics, and an expanding population of surgical and transplant candidates might all contribute to improved long-term survival of these patients. | Adam S Bodzin Ronald W Busuttil | 2015 | World Journal of Hepatology2015，7，9： | 22 |
| 2 | Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation显示文摘Commercial dietary supplements are marketed as a panacea for the morbidly obese seeking sustainable weight-loss. Unfortunately, many claims cited by supplements are unsupported and inadequately regulated. Most concerning, how ever, are the associated harmful side effects, often unrecognized by consumers. Garcinia cambogia extract and Garcinia cambogia containing products are some of the most popular dietary supplements currently marketed for weight loss. Here, we report the first known case of fulminant hepatic failure associated with this dietary supplement. One active ingredient in this supplement is hydroxycitric acid, an active ingredient also found in weight-loss supplements banned by the Food and Drug Administration in 2009 for hepatotoxicity. Heightened awareness of the dangers of dietary supplements such as Garcinia cambogia is imperative to prevent hepatoxicity and potential fulminant hepatic failure in additional patients. | Keri E Lunsford Adam S Bodzin Diego C Reino Hanlin L Wang Ronald W Busuttil | 2016 | World Journal of Gastroenterology2016，22，45： | 3 |
| 3 | Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure显示文摘 | Demetriou A A Brown R S Jr Busuttil R W | 2004 | Ann Surg2004，239，5： | 1 |
| 4 | Support vector ma- chines with profile-based kernels for remote protein homol- ogy detection显示文摘 | BUSUTTIL S ABELA J PACE G J | 2004 | Genome Inform2004，15，： | 1 |
| 5 | Similar Outcomes, Morbidity and mortality for Orthotopic liver transplantation between the very elderly and the young显示文摘 | Rudich S Busuttil R | 1999 | Transplant Proc1999，31，12： | 1 |
| 6 | A role of plasminogen in atherosclerosis and restenosis models in mice 显示文摘 | Ploplis VA Busuttil S | 1999 | Thromb Haemost1999，82，1： | 1 |
| 7 | Transjugular intrahepatie portosystemie shunts in patients with hepatocellular carcinoma 显示文摘 | Lemer S Busuttil R W | 2000 | J Clin Gastroenterol2000，31，3： | 1 |
| 8 | Endoscopic management of biliary leaks after Ttube removal in liver transplant recipients: nasobiliary drainage versus biliary stenting显示文摘 | Saab S Martin P Soliman GY Machicado GA Roth BE Kunder G Han SH Farmer DG Ghobrial RM Busuttil RW Bedford RA | | 0，，： | 1 |
| 9 | Incidence of Acute Rejection in African-American Liver Transplant Recipients显示文摘 | M Maggard J Goss S Ramdev K Swenson R.W Busuttil | 1998 | Transplantation Proceedings1998，，4： | 1 |
| 10 | APOE epsilon4 genotype is associated with an earlier onset of chronic temporal lobe epilepsy 显示文摘 | BRIELLMANN R S TORN-BROERS Y BUSUTTIL B E | 2000 | Neurology2000，55，3： | 1 |
| 11 | Role of p53 in the progression of gastric cancer显示文摘 | Busuttil RA Zapparoli GV Haupt S | 2014 | Oneotarget2014，5，12： | 1 |
| 12 | A central rolefor plasminogen in the inflammatory response to biomaterials显示文摘 | Busuttil S J Ploplis V A Castellino F J | 2004 | Journal of Thrombosis and Haemostasis2004，2，10： | 1 |
| 13 | Prospective,randomized,multicenter controlled trial of a bioartificial liver in treating acute liver failure显示文摘 | Demetriou A A Brown R S J Busuttil R W | | 0，，05： | 1 |
| 14 | Prospectivc, randomized,multicenter, controlled trial of a bioartificial liver in treating acute liver failure显示文摘 | Demetriou A A Brown R S Jr Busuttil R W | 2004 | Ann Surg2004，239，5： | 1 |
| 15 | An interim analysis of a phase Ⅱ/Ⅲ prospective randomized,multicenter,controlled trial of the Hepatassist bioartificial liver support system for the treatment of fulminant hepatic failure显示文摘 | Stevens AC Busuttil R Han S | | 0，，： | 1 |
| 16 | Positive feedback regulation of PLCgammal/Ca(2 +) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway显示文摘 | ALTMAN A KAMINSKI S BUSUTTIL V | 2004 | Eur J Immunol2004，34，7： | 1 |
| 17 | A central role for plasminogen in the inflammatory response to biomaterials显示文摘 | Busuttil S J Ploplis V A Castellino F J | 2004 | J Thromb Haemost2004，2，： | 1 |
| 18 | Role of p53 in the progression of gastric cancer 显示文摘 | Busuttil RA Zapparoli GV Haupt S | 2014 | Oncotarget2014，5，12： | 1 |
| 19 | Impact of taerolimus versus cyclosporine in hepatitis C virus-infected liver transplant recipients on reeurrent hepatitis:a prospeetive randomized trial显示文摘 | Martin P Busuttil R W Goldstein R M Crippin J S Klintmalm G B Fitzsimmons W E | 2004 | Liver Transpl2004，10，： | 1 |
| 20 | Positive feedback regulation of PLCgammal/Ca2^+ signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway 显示文摘 | ALTMAN A KAMINSKI S BUSUTTIL V | 2004 | Eur J Immunol2004，34，7： | 1 |
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