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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Ammonia stripping as a pretreatment for landfill leachate显示文摘 | Cheung K C Chu L M Wong M H | 1997 | Water Air and Soil Pollution1997，94，： | 2 |
| 3 | A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings显示文摘The study of endophenotypes may be a viable strategy to tackle the genetic complexity and phenotypic heterogeneity of psychosis, but this research direction is relatively under-developed in China as compared to Western countries. We have recently initiated one of the first family studies of endophenotypes for psychosis in China. Patients entering an established early psychosis intervention service are recruited into this research project for phenotyping, endophenotyping and genotyping. At the endophenotypic level, four domains (neurological soft signs, neurocognition of prospective memory, social cognition of facial emotion recognition, and affective cognition of anticipatory and consummatory pleasure) are studied in the sample of patients with psychosis and their unaffected siblings. This article illustrates the benefit of a research-oriented clinical programme and its findings based on the data collected as of early 2011. | LUI Simon S Y SHAM Pak CHAN Raymond C K CHEUNG Eric F C | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 4 | Expression of the cystic fibrosis transmembrane conductance regulator in rat spermatids: implication for the site of antispermatogenic agents显示文摘 | Gong X D Li J C Cheung K H | 2001 | Mol Hum Reprod2001，7，8： | 2 |
| 5 | Plates and Tanks on lastic Foundations--An Application on Finite Element Method显示文摘 | CHEUNG Y K Zienkiewicz O C | 1965 | International Journal of Solids and Structures1965，1，1： | 2 |
| 6 | The effect of talc on cell nucleation in extrusion foam processing of polypropylene with CO2 and isopentane显示文摘 | Park C B Cheung L K Song S W | 1998 | Cellular Polymers1998，17，4： | 2 |
| 7 | Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes显示文摘The term 'neurodevelopmental disorder' broadly encompasses conditions thought to arise early in development and includes schizophrenia, bipolar disorder and autism among others. These conditions share a number of genetic and environmental risk factors postulated to lead to common difficulties in socio-emotional processing, communication and cognitive function. The alternative position is that, while the same traits are affected across these conditions, the nature or direction in which they are modified may be distinct. MRI studies provide a rapidly expanding and rich database which we propose can be used to contribute to this debate. Anatomical likelihood estimation (ALE) is a method of meta-analysis applied to voxel-based MRI studies. We have adapted this method to explore the extent to which schizophrenia and bipolar disorder and schizophrenia and autism share a common brain structural phenotype. We will review this work here and discuss whether there is sufficient other evidence to justify a common framework for further research into the inter-relatedness of such conditions. | MCALONAN Grainne M YU Kevin K CHAN Raymond C K CHUA Siew E CHEUNG Charlton | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 8 | Pollutants in Hong Kong soils: Potycyclic aromatic hydrocarbons显示文摘 | CHUNG M K HU R CHEUNG K C | 2007 | Chemosphere2007，67，3： | 1 |
| 9 | Nitrogen and phosphorus leaching from fertilizer applied on golf course: Lysimeter study 显示文摘 | Wong J W C Chan C W Y Cheung K G | 1998 | Water Air and Soil Pollution1998，107，： | 1 |
| 10 | Surface characterization in ultra-precision machining of Al/SiC metal matrix composites using data dependent systems analysis显示文摘 | CHEUNG C F CHAN K C LEE W B | 2003 | Journal of Materials Processing Technology2003，140，： | 1 |
| 11 | MDR1, the blood-brain barrier transporter, is associated with Parkinson's disease in ethnic Chinese 显示文摘 | LEE C G TANG K CHEUNG Y B | 2004 | J Med Genet2004，41，5： | 1 |
| 12 | Performance Evalua- tion of Line Simplification Algorithms for Vector Generalization显示文摘 | Shi Wenzhong Cheung C K | 2006 | The Cartographie Journal2006，43，1： | 1 |
| 13 | An exact solution for three-phase piezoelectric cylinder model under antiplane shear and its applications to piezoelectric composites显示文摘 | Jiang C P Cheung Y K | 2001 | Journal of Solids and Structures2001，38，： | 1 |
| 14 | Ecotoxicological as-sessment of persistent organic and heavy metal contamination in HongKong coastal sediment显示文摘 | WONG C K C YEUNG H Y CHEUNG R Y H | 2000 | Archives of Environmental Contamination andToxicology2000，38，4： | 1 |
| 15 | Hot water extract of the sclerotium of Polyporus rhinocerus Cooke enhances the immune functions of murine macrophages 显示文摘 | Guo C X Wong K H Cheung P C K | 2011 | International Journal of Medicinal Mushrooms2011，13，3： | 1 |
| 16 | Relation of arterial stiffness with gestational age and birth weight 显示文摘 | Cheung Y F Wong K Y Lam B C | 2004 | Arch Dis Child2004，89，3： | 1 |
| 17 | A note on discounted compound renewal sums under dependency 显示文摘 | Woo J K Cheung E C K | 2013 | Insurance: Mathematics and Economics2013，52，2： | 1 |
| 18 | Retinal micro-vasculature as a model to study the manifestations of hyperten- sion显示文摘 | Cheung C Y Ikram M K Sabanayagam C | 2012 | Hypertension2012，60，5： | 1 |
| 19 | Carbene and isocya- nide ligation at luminescent eyclometalated 6-phenyl-2,2-bipyr- idyl platinum ( Ⅱ ) complexesStruetural and spectroseopic显示文摘 | Lai S W Chan M C W Cheung K K | 1999 | Organometallics1999，18，17： | 1 |
| 20 | Effects of the physico-chemical properties of three legume fiber on cholesterol absorption in hamsters 显示文摘 | CHAU C CHEUNG P C K | 1999 | Nutr Res1999，19，2： | 1 |
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