| 1 | A method for assessing nanomaterial dispersion quality based on principal component analysis of particle size distribution data显示文摘Seemingly contradictory findings between studies are a major issue in nanoecotoxicological research and have been explained as a result of the lack of comparability between assay methods,with dispersion of nanomaterials being identified as a key factor.Here we show the use of a multivariate method,principal component analysis(PCA),as a tool in protocol development and categorization of dispersion quality.Results show the significance of particle concentration within a protocol,and its effect on repeatability.Our results suggest that future studies should involve the use of PCA as a powerful data exploration tool to facilitate method development,comparability and integration of data across different laboratories. | R.Tantra C.Oksel K.N.Robinson A.Sikora X.Z.Wang T.A.Wilkins | 2015 | Particuology2015，13，5： | 0 |
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